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Dennis Leung
Dennis Leung
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Year
Selective molecular recognition, C− H bond activation, and catalysis in nanoscale reaction vessels
D Fiedler, DH Leung, RG Bergman, KN Raymond
Accounts of chemical research 38 (4), 349-358, 2005
7682005
Highly selective supramolecular catalyzed allylic alcohol isomerization
DH Leung, RG Bergman, KN Raymond
Journal of the American Chemical Society 129 (10), 2746-2747, 2007
2662007
Selective C H Bond Activation by a Supramolecular Host–Guest Assembly
DH Leung, D Fiedler, RG Bergman, KN Raymond
Angewandte Chemie International Edition 43 (8), 963-966, 2004
2522004
Enantioselective guest binding and dynamic resolution of cationic ruthenium complexes by a chiral metal− ligand assembly
D Fiedler, DH Leung, RG Bergman, KN Raymond
Journal of the American Chemical Society 126 (12), 3674-3675, 2004
1942004
Scope and mechanism of the C− H bond activation reactivity within a supramolecular host by an iridium guest: a stepwise ion pair guest dissociation mechanism
DH Leung, RG Bergman, KN Raymond
Journal of the American Chemical Society 128 (30), 9781-9797, 2006
1842006
Enthalpy− entropy compensation reveals solvent reorganization as a driving force for supramolecular encapsulation in water
DH Leung, RG Bergman, KN Raymond
Journal of the American Chemical Society 130 (9), 2798-2805, 2008
1642008
Axial donating ligands: a new strategy for late transition metal olefin polymerization catalysis
DH Leung, JW Ziller, Z Guan
Journal of the American Chemical Society 130 (24), 7538-7539, 2008
1382008
Physicochemical and formulation developability assessment for therapeutic peptide delivery—a primer
A Bak, D Leung, SE Barrett, S Forster, EC Minnihan, AW Leithead, ...
The AAPS journal 17, 144-155, 2015
882015
Platinum and palladium imido and oxo complexes with small natural bite angle diphosphine ligands
U Anandhi, T Holbert, D Lueng, PR Sharp
Inorganic chemistry 42 (4), 1282-1295, 2003
622003
A new and improved method for the preparation of drug nanosuspension formulations using acoustic mixing technology
DH Leung, DJ Lamberto, L Liu, E Kwong, T Nelson, T Rhodes, A Bak
International Journal of Pharmaceutics 473 (1-2), 10-19, 2014
492014
Two novel pharmaceutical cocrystals of a development compound–screening, scale-up, and characterization
DH Leung, S Lohani, RG Ball, N Canfield, Y Wang, T Rhodes, A Bak
Crystal growth & design 12 (3), 1254-1262, 2012
482012
Development of a Convenient In Vitro Gel Diffusion Model for Predicting the In Vivo Performance of Subcutaneous Parenteral Formulations of Large and Small …
DH Leung, Y Kapoor, C Alleyne, E Walsh, A Leithead, B Habulihaz, ...
AAPS PharmSciTech 18, 2203-2213, 2017
372017
Towards an improved understanding of drug excipient interactions to enable rapid optimization of nanosuspension formulations
JA Ferrar, BD Sellers, C Chan, DH Leung
International Journal of Pharmaceutics 578, 119094, 2020
352020
Design, synthesis, and evaluation of novel and selective G-protein coupled receptor 120 (GPR120) spirocyclic agonists
JM Cox, HD Chu, MV Chelliah, JS Debenham, K Eagen, P Lan, ...
ACS Medicinal Chemistry Letters 8 (1), 49-54, 2017
342017
Automated high-throughput preparation and characterization of oligonucleotide-loaded lipid nanoparticles
Y Fan, CW Yen, HC Lin, W Hou, A Estevez, A Sarode, A Goyon, J Bian, ...
International journal of pharmaceutics 599, 120392, 2021
322021
Discovery of benzofuran propanoic acid GPR120 agonists: From uHTS hit to mechanism-based pharmacodynamic effects
M Lombardo, K Bender, C London, MA Plotkin, M Kirkland, J Mane, ...
Bioorganic & Medicinal Chemistry Letters 26 (23), 5724-5728, 2016
292016
Predictive high-throughput screening of PEGylated lipids in oligonucleotide-loaded lipid nanoparticles for neuronal gene silencing
A Sarode, Y Fan, AE Byrnes, M Hammel, GL Hura, Y Fu, P Kou, C Hu, ...
Nanoscale advances 4 (9), 2107-2123, 2022
262022
Modulating drug release and enhancing the oral bioavailability of torcetrapib with solid lipid dispersion formulations
Y Liu, GM Salituro, K Lee, A Bak, DH Leung
AAPS PharmSciTech 16, 1091-1100, 2015
232015
A novel method for preparing stabilized amorphous solid dispersion drug formulations using acoustic fusion
Z Guo, C Boyce, T Rhodes, L Liu, GM Salituro, K Lee, A Bak, DH Leung
International Journal of Pharmaceutics 592, 120026, 2021
212021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a 5-Fluoro-4-(3H)-quinazolinone Aryl Urea pan-RAF Kinase Inhibitor
MP Huestis, D Dela Cruz, AG DiPasquale, MR Durk, C Eigenbrot, ...
Journal of Medicinal Chemistry 64 (7), 3940-3955, 2021
192021
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