Prolyl hydroxylase inhibitors: a breakthrough in the therapy of anemia associated with chronic diseases AA Joharapurkar, VB Pandya, VJ Patel, RC Desai, MR Jain Journal of medicinal chemistry 61 (16), 6964-6982, 2018 | 157 | 2018 |
Role of mineralocorticoid receptor antagonists in kidney diseases V Patel, A Joharapurkar, M Jain Drug development research 82 (3), 341-363, 2021 | 54 | 2021 |
Effect of GLP-1 based therapies on diabetic dyslipidemia V J Patel, A A Joharapurkar, G B Shah, M R Jain Current diabetes reviews 10 (4), 238-250, 2014 | 53 | 2014 |
Co-agonist of glucagon and GLP-1 reduces cholesterol and improves insulin sensitivity independent of its effect on appetite and body weight in diet-induced obese C57 mice V Patel, A Joharapurkar, N Dhanesha, S Kshirsagar, K Patel, R Bahekar, ... Canadian Journal of Physiology and Pharmacology 91 (12), 1009-1015, 2013 | 40 | 2013 |
Inhibition of microsomal triglyceride transfer protein improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats V Dhote, A Joharapurkar, S Kshirsagar, N Dhanesha, V Patel, A Patel, ... Clinical and Experimental Pharmacology and Physiology 38 (5), 338-344, 2011 | 38 | 2011 |
Coagonist of GLP-1 and glucagon receptor ameliorates development of non-alcoholic fatty liver disease V Patel, A Joharapurkar, S Kshirsagar, B Sutariya, M Patel, H Patel, ... Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly …, 2018 | 36 | 2018 |
Combination of omeprazole with GLP-1 agonist therapy improves insulin sensitivity and antioxidant activity in liver in type 1 diabetic mice V Patel, A Joharapurkar, N Dhanesha, S Kshirsagar, J Detroja, K Patel, ... Pharmacological Reports 65 (4), 927-936, 2013 | 31 | 2013 |
Pharmacological characterization of ZYAN1, a novel prolyl hydroxylase inhibitor for the treatment of anemia MR Jain, AA Joharapurkar, V Pandya, V Patel, J Joshi, S Kshirsagar, ... Drug research 66 (02), 107-112, 2016 | 28 | 2016 |
Treatment with exendin-4 improves the antidiabetic efficacy and reverses hepatic steatosis in glucokinase activator treated db/db mice N Dhanesha, A Joharapurkar, G Shah, S Kshirsagar, V Patel, K Patel, ... European journal of pharmacology 714 (1-3), 188-192, 2013 | 24 | 2013 |
Omeprazole improves the anti‐obesity and antidiabetic effects of exendin‐4 in db/db mice (奥美拉唑改善唾液素‐4 对db/db小鼠的减肥与降糖作用)* V Patel, A Joharapurkar, T Gandhi, K Patel, N Dhanesha, S Kshirsagar, ... Journal of diabetes 5 (2), 163-171, 2013 | 21 | 2013 |
Coagonist of GLP-1 and glucagon decreases liver inflammation and atherosclerosis in dyslipidemic condition V Patel, A Joharapurkar, S Kshirsagar, B Sutariya, M Patel, D Pandey, ... Chemico-biological interactions 282, 13-21, 2018 | 19 | 2018 |
Pharmacological inhibition of prolyl hydroxylase protects against inflammation-induced anemia via efficient erythropoiesis and hepcidin downregulation M Jain, A Joharapurkar, V Patel, S Kshirsagar, B Sutariya, M Patel, ... European Journal of Pharmacology 843, 113-120, 2019 | 18 | 2019 |
Central GLP-1 receptor activation improves cholesterol metabolism partially independent of its effect on food intake V Patel, AA Joharapurkar, SG Kshirsagar, KN Patel, R Bahekar, G Shah, ... Canadian journal of physiology and pharmacology 94 (2), 161-167, 2016 | 17 | 2016 |
Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates nonalcoholic fatty liver disease V Patel, A Joharapurkar, S Kshirsagar, M Patel, B Sutariya, H Patel, ... Canadian Journal of Physiology and Pharmacology 96 (6), 587-596, 2018 | 16 | 2018 |
Central and peripheral glucagon reduces hyperlipidemia in rats and hamsters V Patel, A Joharapurkar, S Kshirsagar, HM Patel, D Pandey, D Patel, ... Drug research 67 (06), 318-326, 2017 | 16 | 2017 |
Central administration of coagonist of GLP-1 and glucagon receptors improves dyslipidemia V Patel, A Joharapurkar, S Kshirsagar, B Sutariya, M Patel, H Patel, ... Biomedicine & Pharmacotherapy 98, 364-371, 2018 | 14 | 2018 |
Balanced coagonist of GLP-1 and glucagon receptors corrects dyslipidemia by improving FGF21 sensitivity in hamster model V Patel, A Joharapurkar, S Kshirsagar, HM Patel, D Pandey, D Patel, ... Drug research 67 (12), 730-736, 2017 | 14 | 2017 |
Influence of acute and chronic kidney failure in rats on the disposition and pharmacokinetics of ZYAN1, a novel prolyl hydroxylase inhibitor, for the treatment of chronic … H Patel, AA Joharapurkar, VB Pandya, VJ Patel, SG Kshirsagar, P Patel, ... Xenobiotica 48 (1), 37-44, 2018 | 13 | 2018 |
Therapeutic potential of coagonists of glucagon and GLP-1 V J Patel, A A Joharapurkar, S G Kshirsagar, K N Patel, G B Shah, ... Cardiovascular & Hematological Agents in Medicinal Chemistry (Formerly …, 2014 | 13 | 2014 |
Cannabinoid receptor 1 antagonist treatment induces glucagon release and shows an additive therapeutic effect with GLP-1 agonist in diet-induced obese mice KN Patel, AA Joharapurkar, V Patel, SG Kshirsagar, R Bahekar, ... Canadian Journal of Physiology and Pharmacology 92 (12), 975-983, 2014 | 13 | 2014 |