Erdal Toprak, PhD
Erdal Toprak, PhD
University of Texas Southwestern Medical Center, Green Center for Systems Biology
Verified email at - Homepage
Cited by
Cited by
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection
E Toprak, A Veres, JB Michel, R Chait, DL Hartl, R Kishony
Nature Genetics 44 (1), 101-105, 2011
Three-dimensional particle tracking via bifocal imaging
E Toprak, H Balci, BH Blehm, PR Selvin
Nano letters 7 (7), 2043-2045, 2007
Defocused orientation and position imaging (DOPI) of myosin V
E Toprak, J Enderlein, S Syed, SA McKinney, RG Petschek, T Ha, ...
Proceedings of the National Academy of Sciences 103 (17), 6495-6499, 2006
Strength of selection pressure is an important parameter contributing to the complexity of antibiotic resistance evolution
T Oz, A Guvenek, S Yildiz, E Karaboga, YT Tamer, N Mumcuyan, VB Ozan, ...
Molecular biology and evolution 31 (9), 2387-2401, 2014
Polarization effect on position accuracy of fluorophore localization
J Enderlein, E Toprak, PR Selvin
Optics express 14 (18), 8111-8120, 2006
Building a morbidostat: an automated continuous-culture device for studying bacterial drug resistance under dynamically sustained drug inhibition
E Toprak, A Veres, S Yildiz, JM Pedraza, R Chait, J Paulsson, R Kishony
Nature protocols 8 (3), 555-567, 2013
Delayed commitment to evolutionary fate in antibiotic resistance fitness landscapes
AC Palmer, E Toprak, M Baym, S Kim, A Veres, S Bershtein, R Kishony
Nature communications 6 (1), 1-8, 2015
Why kinesin is so processive
E Toprak, A Yildiz, MT Hoffman, SS Rosenfeld, PR Selvin
Proceedings of the National Academy of Sciences 106 (31), 12717-12722, 2009
Quantifying the determinants of evolutionary dynamics leading to drug resistance
G Chevereau, M Dravecká, T Batur, A Guvenek, DH Ayhan, E Toprak, ...
PLoS biology 13 (11), e1002299, 2015
New fluorescent tools for watching nanometer-scale conformational changes of single molecules
E Toprak, PR Selvin
Annual review of biophysics and biomolecular structure 36 (1), 349-369, 2007
Single-molecule fluorescence to study molecular motors
H Park, E Toprak, PR Selvin
Quarterly reviews of biophysics 40 (1), 87-111, 2007
Sequence-specific targeting of bacterial resistance genes increases antibiotic efficacy
DH Ayhan, YT Tamer, M Akbar, SM Bailey, M Wong, SM Daly, ...
PLoS biology 14 (9), e1002552, 2016
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells
B Okumus, D Landgraf, GC Lai, S Bakshi, JC Arias-Castro, S Yildiz, ...
Nature communications 7 (1), 1-11, 2016
High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection
YT Tamer, IK Gaszek, H Abdizadeh, TA Batur, KA Reynolds, AR Atilgan, ...
Molecular biology and evolution 36 (7), 1533-1550, 2019
Fluorescence imaging with one-nanometer accuracy (FIONA)
PR Selvin, T Lougheed, MT Hoffman, H Park, H Balci, BH Blehm, ...
Cold Spring Harbor Protocols 2007 (10), pdb. top27, 2007
Myosin VI undergoes a 180 power stroke implying an uncoupling of the front lever arm
JG Reifenberger, E Toprak, HJ Kim, D Safer, HL Sweeney, PR Selvin
Proceedings of the National Academy of Sciences 106 (43), 18255-18260, 2009
Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance
H Abdizadeh, YT Tamer, O Acar, E Toprak, AR Atilgan, C Atilgan
Physical Chemistry Chemical Physics 19 (18), 11416-11428, 2017
Fluidic and microfluidic tools for quantitative systems biology
B Okumus, S Yildiz, E Toprak
Current opinion in biotechnology 25, 30-38, 2014
Super-accuracy and super-resolution: Getting around the diffraction limit
E Toprak, C Kural, PR Selvin
Methods in enzymology 475, 1-26, 2010
A trimethoprim derivative impedes antibiotic resistance evolution
MS Manna, YT Tamer, I Gaszek, N Poulides, A Ahmed, X Wang, ...
Nature communications 12 (1), 1-10, 2021
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