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Frank Schoenen
Frank Schoenen
Verified email at ku.edu
Title
Cited by
Cited by
Year
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ...
Nature 385 (6618), 733-736, 1997
21091997
Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor
GM McGeehan, JD Becherer, RC Bast Jr, CM Boyer, B Champion, ...
Nature 370 (6490), 558-561, 1994
7241994
Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
TF Chou, SJ Brown, D Minond, BE Nordin, K Li, AC Jones, P Chase, ...
Proceedings of the National Academy of Sciences 108 (12), 4834-4839, 2011
3572011
Combinatorial compound libraries for drug discovery: an ongoing challenge
H Mario Geysen, F Schoenen, D Wagner, R Wagner
Nature Reviews Drug Discovery 2 (3), 222-230, 2003
3182003
A new glucocerebrosidase chaperone reduces α-synuclein and glycolipid levels in iPSC-derived dopaminergic neurons from patients with Gaucher disease and parkinsonism
E Aflaki, DK Borger, N Moaven, BK Stubblefield, SA Rogers, S Patnaik, ...
Journal of Neuroscience 36 (28), 7441-7452, 2016
2292016
Transannular Diels-Alder route to systems related to dynemicin A
JA Porco Jr, FJ Schoenen, TJ Stout, J Clardy, SL Schreiber
Journal of the American Chemical Society 112 (20), 7410-7411, 1990
2111990
Isotope or mass encoding of combinatorial libraries
HM Geysen, CD Wagner, WM Bodnar, CJ Markworth, GJ Parke, ...
Chemistry & Biology 3 (8), 679-688, 1996
1911996
Structural features and biochemical properties of TNF-α converting enzyme (TACE)
ML Moss, SLC Jin, JD Becherer, DM Bickett, W Burkhart, WJ Chen, ...
Journal of neuroimmunology 72 (2), 127-129, 1997
1721997
Advancing biological understanding and therapeutics discovery with small-molecule probes
SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ...
Cell 161 (6), 1252-1265, 2015
1642015
Structure–activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase
TF Chou, K Li, KJ Frankowski, FJ Schoenen, RJ Deshaies
ChemMedChem 8 (2), 297-312, 2013
1482013
Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains
TF Chou, SL Bulfer, CC Weihl, K Li, LG Lis, MA Walters, FJ Schoenen, ...
Journal of molecular biology 426 (15), 2886-2899, 2014
1212014
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication
S Mukherjee, WS Weiner, CE Schroeder, DS Simpson, AM Hanson, ...
ACS chemical biology 9 (10), 2393-2403, 2014
852014
VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination …
P Bastola, L Neums, FJ Schoenen, J Chien
Molecular oncology 10 (10), 1559-1574, 2016
832016
Optimization of potent hepatitis C virus NS3 helicase inhibitors isolated from the yellow dyes thioflavine S and primuline
K Li, KJ Frankowski, CA Belon, B Neuenswander, J Ndjomou, AM Hanson, ...
Journal of medicinal chemistry 55 (7), 3319-3330, 2012
732012
Targeting p97 to disrupt protein homeostasis in cancer
PH Vekaria, T Home, S Weir, FJ Schoenen, R Rao
Frontiers in oncology 6, 181, 2016
712016
An enolate claisen route to c-pyranosides: Development and application to an ionophore synthon
SD Burke, DM Armistead, FJ Schoenen, JM Fevig
Tetrahedron 42 (11), 2787-2801, 1986
711986
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis
KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ...
Science translational medicine 10 (441), eaap8307, 2018
652018
Matrix Metalloproteinase Inhibitors Containing a [(Carboxyalkyl) amino] zinc Ligand: Modification of the P1 and P2'Residues
FK Brown, PJ Brown, DM Bickett, CL Chambers, HG Davies, DN Deaton, ...
Journal of medicinal chemistry 37 (5), 674-688, 1994
641994
Benzothiazole and pyrrolone flavivirus inhibitors targeting the viral helicase
NL Sweeney, AM Hanson, S Mukherjee, J Ndjomou, BJ Geiss, JJ Steel, ...
ACS infectious diseases 1 (3), 140-148, 2015
592015
Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis
B Gold, R Smith, Q Nguyen, J Roberts, Y Ling, L Lopez Quezada, ...
Journal of medicinal chemistry 59 (13), 6027-6044, 2016
572016
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