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Iuliia Dubova
Iuliia Dubova
Verified email at health.missouri.edu
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Mast cells in stress, pain, blood-brain barrier, neuroinflammation and Alzheimer’s disease
D Kempuraj, S Mentor, R Thangavel, ME Ahmed, GP Selvakumar, ...
Frontiers in cellular neuroscience 13, 448252, 2019
1052019
Targeted gene editing of glia maturation factor in microglia: a novel Alzheimer’s disease therapeutic target
SP Raikwar, R Thangavel, I Dubova, GP Selvakumar, ME Ahmed, ...
Molecular neurobiology 56, 378-393, 2019
582019
Brain injury–mediated neuroinflammatory response and Alzheimer’s disease
D Kempuraj, ME Ahmed, GP Selvakumar, R Thangavel, AS Dhaliwal, ...
The Neuroscientist 26 (2), 134-155, 2020
572020
Mast cell proteases activate astrocytes and glia-neurons and release interleukin-33 by activating p38 and ERK1/2 MAPKs and NF-κB
D Kempuraj, R Thangavel, GP Selvakumar, ME Ahmed, S Zaheer, ...
Molecular neurobiology 56, 1681-1693, 2019
572019
NLRP3 inflammasome and glia maturation factor coordinately regulate neuroinflammation and neuronal loss in MPTP mouse model of Parkinson’s disease
H Javed, R Thangavel, GP Selvakumar, I Dubova, N Schwartz, ...
International immunopharmacology 83, 106441, 2020
362020
Next generation precision medicine: CRISPR-mediated genome editing for the treatment of neurodegenerative disorders
SP Raikwar, NS Kikkeri, R Sakuru, D Saeed, H Zahoor, K Premkumar, ...
Journal of Neuroimmune Pharmacology 14, 608-641, 2019
292019
Glia maturation factor and mast cell-dependent expression of inflammatory mediators and proteinase activated receptor-2 in neuroinflammation
D Kempuraj, GP Selvakumar, R Thangavel, ME Ahmed, S Zaheer, ...
Journal of Alzheimer's Disease 66 (3), 1117-1129, 2018
282018
CRISPR/Cas9 editing of glia maturation factor regulates mitochondrial dynamics by attenuation of the NRF2/HO-1 dependent ferritin activation in glial cells
GP Selvakumar, ME Ahmed, SP Raikwar, R Thangavel, D Kempuraj, ...
Journal of Neuroimmune Pharmacology 14, 537-550, 2019
262019
Synergy in disruption of mitochondrial dynamics by Aβ (1-42) and glia maturation factor (GMF) in SH-SY5Y cells is mediated through alterations in fission and fusion proteins
ME Ahmed, GP Selvakumar, D Kempuraj, R Thangavel, S Mentor, ...
Molecular neurobiology 56, 6964-6975, 2019
232019
Neuro-immuno-gene-and genome-editing-therapy for Alzheimer’s disease: are we there yet?
SP Raikwar, R Thangavel, I Dubova, ME Ahmed, PG Selvakumar, ...
Journal of Alzheimer's Disease 65 (2), 321-344, 2018
222018
A role for glia maturation factor dependent activation of mast cells and microglia in MPTP induced dopamine loss and behavioural deficits in mice
GP Selvakumar, ME Ahmed, R Thangavel, D Kempuraj, I Dubova, ...
Brain, behavior, and immunity 87, 429-443, 2020
212020
Are Tanycytes the missing link between Type 2 Diabetes and Alzheimer’s Disease?
SP Raikwar, SM Bhagavan, SB Ramaswamy, R Thangavel, I Dubova, ...
Molecular neurobiology 56, 833-843, 2019
152019
Molecular association of glia maturation factor with the autophagic machinery in rat dopaminergic neurons: a role for endoplasmic reticulum stress and MAPK activation
GP Selvakumar, SS Iyer, D Kempuraj, ME Ahmed, R Thangavel, I Dubova, ...
Molecular neurobiology 56, 3865-3881, 2019
112019
Neuroinflammation Mediated by Glia Maturation Factor Exacerbates Neuronal Injury in an in vitro Model of Traumatic Brain Injury
ME Ahmed, GP Selvakumar, D Kempuraj, SP Raikwar, R Thangavel, ...
Journal of Neurotrauma 37 (14), 1645-1655, 2020
92020
Glia Maturation Factor Dependent Mast Cell Activation and Calpain 1 Synergize Dopaminergic Neuronal Loss and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease
SG Pushpavathi, K Duraisamy, ME Ahmed, R Thangavel, I Dubova, ...
The FASEB Journal 33 (S1), 791.7-791.7, 2019
22019
Parkinson’s Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain
R Thangavel, H Kaur, I Dubova, GP Selvakumar, ME Ahmed, SP Raikwar, ...
International Journal of Molecular Sciences 25 (2), 1182, 2024
12024
P4‐509: SUPPRESSION OF NEUROINFLAMMATION AND AMYLOID PATHOLOGY IN 5XFAD MICE BRAIN BY GLIA MATURATION FACTOR ANTIBODY
ME Ahmed, R Thangavel, GP Selvakumar, DP Kempuraj, IP Dubova, ...
Alzheimer's & Dementia 15, P1508-P1508, 2019
2019
Glia Maturation Factor‐Antibody Injection Reduces Behavioral Impairment, Neuro Inflammation and Amyloid Pathology in 5XFAD Mice Brains
ME Ahmed, R Thangavel, GP Selvakumar, D Kempuraj, I Dubova, ...
The FASEB Journal 33 (S1), 791.1-791.1, 2019
2019
Glia Maturation Factor Gene Editing Improves Neurocognitive Function in an Alzheimer's Disease Mouse Model
SP Raikwar, ME Ahmed, I Dubova, S Mentor, D Saeed, H Zahoor, ...
The FASEB Journal 33 (S1), 620.10-620.10, 2019
2019
Engineering Micro-Indels in Glia Maturation Factor: a Novel Alzheimer's Disease Therapeutic Target
SP Raikwar, R Thangavel, I Dubova, GP Selvakumar, ME Ahmed, G Giler, ...
MOLECULAR THERAPY 26 (5), 139-140, 2018
2018
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