Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition L Chen, W Chen, M Mysliwski, J Serio, J Ropa, FA Abulwerdi, RJ Chan, ... Leukemia, 2015 | 65 | 2015 |
Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner S He, B Malik, D Borkin, H Miao, S Shukla, K Kempinska, T Purohit, ... Leukemia 30 (2), 508-513, 2016 | 47 | 2016 |
The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia J Serio, J Ropa, W Chen, M Mysliwski, N Saha, L Chen, J Wang, H Miao, ... Oncogene 37 (4), 450-460, 2018 | 41 | 2018 |
Differential regulation of the c-Myc/Lin28 axis discriminates subclasses of rearranged MLL leukemia L Chen, Y Sun, J Wang, H Jiang, AG Muntean Oncotarget, 2016 | 32 | 2016 |
Predicting MDCK cell permeation coefficients of organic molecules using membrane‐interaction QSAR analysis L Chen, J Yao, J Yang, J YANG Acta Pharmacologica Sinica 26 (11), 1322-1333, 2005 | 28 | 2005 |
The PAF1c subunit CDC73 is required for mouse hematopoietic stem cell maintenance but displays leukemia-specific gene regulation N Saha, J Ropa, L Chen, H Hu, M Mysliwski, A Friedman, I Maillard, ... Stem Cell Reports 12 (5), 1069-1083, 2019 | 16 | 2019 |
Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity L Chen, E Reyes-Vargas, H Dai, H Escobar, B Rudd, J Fairbanks, A Ho, ... The Journal of Immunology 193 (3), 1427-1439, 2014 | 10 | 2014 |
An MHC class Ib-restricted CD8+ T cell response to lymphocytic choriomeningitis virus L Chen, DC Jay, JD Fairbanks, X He, PE Jensen The Journal of Immunology 187 (12), 6463-6472, 2011 | 10 | 2011 |
Construction of drug screening cell model and application to new compounds inhibiting FITC-fibrinogen binding to CHO cells expressing human αIIbβ3 J Yang, J Yao, J Chen, XN Wang, TY Zhu, LL Chen, P Chu European journal of pharmacology 618 (1-3), 1-8, 2009 | 7 | 2009 |
The Amino-terminal domain of integrin β3 functions as a transcriptional activator in yeast J Yang, J Yao, L Chen, J Yang Molecular and cellular biochemistry 288 (1-2), 1-5, 2006 | 4 | 2006 |
The PAF1c Subunit Cdc73 Is Essential for Hematopoiesis and Displays Differential Gene Regulation in MLL-AF9 Driven Leukemia S Nirmalya, J Ropa, L Chen, HY Hu, M Mysliwski, A Friedman, I Maillard, ... Blood 132, 1280, 2018 | 1 | 2018 |
The role of the ASH1L SET domain in leukemogenesis D Rogawski, H Miao, K Kempinska, L Chen, J Chase, A Friedman, X Yan, ... Cancer Research 77 (13_Supplement), 1373-1373, 2017 | | 2017 |
Novel Protein Interactions Provide Insight into the Regulation of the Polymerase Associated Factor Complex in Acute Myeloid Leukemia J Ropa, J Serio, L Chen, W Chen, M Mysliwski, D Mellacheruvu, V Basrur, ... The FASEB Journal 31, 933.3-933.3, 2017 | | 2017 |
The PAF Complex Regulation of Prmt5 Facilitates Leukemic Progression J Serio, W Chen, M Mysliwski, L Chen, J Ropa, J Wang, AG Muntean Blood 128 (22), 3914, 2016 | | 2016 |
Differential Regulation of c-Myc/Lin28 Discriminates Subclasses of Rearranged MLL Leukemia L Chen, Y Sun, J Wang, H Jiang, AG Muntean Blood 126 (23 (Meeting Abstracts)), 163, 2015 | | 2015 |
Characterization of the Molecular Interplay Between HOXA9 and Ogt in Leukemia JFM Rual, T Xu, C Collins, H Zhang, J Wang, R Kuick, J Bronstein, ... Blood 124 (21), 3533, 2014 | | 2014 |
Hyperactive Ptpn11 Mutations Alters Leukemic Stem Cell Frequency through Mcl-1 Overexpression L Chen, W Chen, M Mysliwski, J Serio, J Ropa, F Abulwerdi, RJ Chan, ... Blood 124 (21), 3565, 2014 | | 2014 |
Murine MHC class Ib gene T11: a functional paralog of T23/Qa-1?(106.42) L Chen, X He, A Kumanovics, J Fairbanks, P Jensen The Journal of Immunology 188 (1_Supplement), 106.42-106.42, 2012 | | 2012 |
The study of MHC class Ib molecules and MHC class Ib-restricted CD8+ T cell responses L Chen The University of Utah, 2012 | | 2012 |
An MHC Class Ib-Restricted CD8 PE Jensen, L Chen, DC Jay, JD Fairbanks, X He | | 2011 |