| The high Nrf2 expression in human acute myeloid leukemia is driven by NF-κB and underlies its chemo-resistance SA Rushworth, L Zaitseva, MY Murray, NM Shah, KM Bowles, ... Blood, The Journal of the American Society of Hematology 120 (26), 5188-5198, 2012 | 315 | 2012 |
| Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment MS Shafat, T Oellerich, S Mohr, SD Robinson, DR Edwards, CR Marlein, ... Blood, The Journal of the American Society of Hematology 129 (10), 1320-1332, 2017 | 296 | 2017 |
| NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts CR Marlein, L Zaitseva, RE Piddock, SD Robinson, DR Edwards, ... Blood, The Journal of the American Society of Hematology 130 (14), 1649-1660, 2017 | 291 | 2017 |
| Lipopolysaccharide-induced expression of NAD (P) H: quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes SA Rushworth, DJ MacEwan, MA O'Connell The Journal of Immunology 181 (10), 6730-6737, 2008 | 249 | 2008 |
| Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C SA Rushworth, XL Chen, N Mackman, RM Ogborne, MA O’Connell The Journal of Immunology 175 (7), 4408-4415, 2005 | 220 | 2005 |
| Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes SA Rushworth, RM Ogborne, CA Charalambos, MA O’Connell Biochemical and biophysical research communications 341 (4), 1007-1016, 2006 | 192 | 2006 |
| CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma CR Marlein, RE Piddock, JJ Mistry, L Zaitseva, C Hellmich, RH Horton, ... Cancer Research 79 (9), 2285-2297, 2019 | 179 | 2019 |
| HO-1 underlies resistance of AML cells to TNF-induced apoptosis SA Rushworth, DJ MacEwan Blood, The Journal of the American Society of Hematology 111 (7), 3793-3801, 2008 | 176 | 2008 |
| Ibrutinib in relapsed chronic lymphocytic leukemia. S Rushworth, D MacEwan, K Bowles New England Journal of Medicine 369 (13), 1277-8, 2013 | 170* | 2013 |
| The bone marrow microenvironment–Home of the leukemic blasts MS Shafat, B Gnaneswaran, KM Bowles, SA Rushworth Blood reviews 31 (5), 277-286, 2017 | 147 | 2017 |
| Identification of Bruton’s tyrosine kinase as a therapeutic target in acute myeloid leukemia SA Rushworth, MY Murray, L Zaitseva, KM Bowles, DJ MacEwan Blood, The Journal of the American Society of Hematology 123 (8), 1229-1238, 2014 | 140 | 2014 |
| BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB SA Rushworth, KM Bowles, LN Barrera, MY Murray, L Zaitseva, ... Cellular signalling 25 (1), 106-112, 2013 | 128 | 2013 |
| α-lipoic acid–induced heme oxygenase-1 expression is mediated by nuclear factor erythroid 2-related factor 2 and p38 mitogen-activated protein kinase in human monocytic cells RM Ogborne, SA Rushworth, MA O’Connell Arteriosclerosis, thrombosis, and vascular biology 25 (10), 2100-2105, 2005 | 124 | 2005 |
| High basal nuclear levels of Nrf2 in acute myeloid leukemia reduces sensitivity to proteasome inhibitors SA Rushworth, KM Bowles, DJ MacEwan Cancer research 71 (5), 1999-2009, 2011 | 105 | 2011 |
| Curcumin: potential for hepatic fibrosis therapy? MA O'Connell, SA Rushworth British journal of pharmacology 153 (3), 403-405, 2008 | 97 | 2008 |
| ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection JJ Mistry, CR Marlein, JA Moore, C Hellmich, EE Wojtowicz, JGW Smith, ... Proceedings of the National Academy of Sciences 116 (49), 24610-24619, 2019 | 95 | 2019 |
| MIF-induced stromal PKCβ/IL8 is essential in human acute myeloid leukemia AM Abdul-Aziz, MS Shafat, TK Mehta, F Di Palma, MJ Lawes, ... Cancer research 77 (2), 303-311, 2017 | 88 | 2017 |
| Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1 SA Heasman, L Zaitseva, KM Bowles, SA Rushworth, DJ MacEwan Oncotarget 2 (9), 658, 2011 | 88 | 2011 |
| TNF mediates the sustained activation of Nrf2 in human monocytes SA Rushworth, S Shah, DJ MacEwan The Journal of immunology 187 (2), 702-707, 2011 | 86 | 2011 |
| Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment AM Abdul-Aziz, Y Sun, C Hellmich, CR Marlein, J Mistry, E Forde, ... Blood, The Journal of the American Society of Hematology 133 (5), 446-456, 2019 | 83 | 2019 |
