Martin J Baker
Martin J Baker
Division of Cancer Sciences, University of Manchester
Verified email at
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The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues
AKE Johnsson, Y Dai, M Nobis, MJ Baker, EJ McGhee, S Walker, ...
Cell reports 6 (6), 1153-1164, 2014
The role of Rac in tumor susceptibility and disease progression: from biochemistry to the clinic
V Casado-Medrano, MJ Baker, C Lopez-Haber, M Cooke, S Wang, ...
Biochemical Society Transactions 46 (4), 1003-1012, 2018
Norbin stimulates the catalytic activity and plasma membrane localization of the guanine-nucleotide exchange factor P-Rex1
D Pan, MA Barber, K Hornigold, MJ Baker, JM Toth, D Oxley, HCE Welch
Journal of Biological Chemistry, jbc. M115. 686592, 2016
Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment
MJ Baker, D Pan, HCE Welch
Current opinion in hematology 23 (1), 44-54, 2016
Characterization of AJH-836, a DAG-lactone with selectivity for novel PKC isozymes
M Cooke, X Zhou, V Casado-Medrano, C Lopez-Haber, MJ Baker, R Garg, ...
Journal of Biological Chemistry, jbc. RA117. 000235, 2018
Rac-GEF/Rac signaling and metastatic dissemination in lung cancer
M Cooke, MJ Baker, MG Kazanietz
Frontiers in Cell and Developmental Biology 8, 118, 2020
Nuclear PKCι-ECT2-Rac1 and ribosome biogenesis: a novel axis in lung tumorigenesis
MJ Baker, M Cooke, MG Kazanietz
Cancer cell 31 (2), 167-169, 2017
FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
M Cooke, G Kreider-Letterman, MJ Baker, S Zhang, NT Sullivan, ...
Cell Reports 37 (5), 109905, 2021
The PKC universe keeps expanding: From cancer initiation to metastasis
N Rahimova, M Cooke, S Zhang, MJ Baker, MG Kazanietz
Advances in Biological Regulation 78, 100755, 2020
PKCε regulates Rho GTPases and actin cytoskeleton reorganization in non-small cell lung cancer cells
M Cooke, MJ Baker, MG Kazanietz, V Casado-Medrano
Small GTPases 12 (3), 202-208, 2019
The P-Rex1/Rac signaling pathway as a point of convergence for HER/ErbB receptor and GPCR responses
MG Kazanietz, L Barrio-Real, V Casado-Medrano, MJ Baker, ...
Small GTPases, 1-7, 2016
Activating RAC1 variants in the switch II region cause a developmental syndrome and alter neuronal morphology
S Banka, A Bennington, MJ Baker, E Rijckmans, G Clemente, NM Ansor, ...
Brain, 2022
P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer
MJ Baker, MC Abba, R Garcia-Mata, MG Kazanietz
Cancers 12 (2), 480, 2020
Evaluation of active Rac1 levels in cancer cells: A case of misleading conclusions from immunofluorescence analysis
MJ Baker, M Cooke, G Kreider-Letterman, R Garcia-Mata, PA Janmey, ...
Journal of Biological Chemistry 295 (40), 13698-13710, 2020
Mechanical strain stimulates COPII‐dependent secretory trafficking via Rac1
S Phuyal, E Djaerff, AL Le Roux, MJ Baker, D Fankhauser, ...
The EMBO Journal 41 (18), e110596, 2022
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection
C Pantarelli, D Pan, S Chetwynd, AK Stark, K Hornigold, P Machin, ...
Blood Advances 5 (16), 3076-3091, 2021
Active GTPase Pulldown Protocol
MJ Baker, I Rubio
Ras Activity and Signaling, 117-135, 2021
Germline intergenic duplications at Xq26.1 underlie Bazex‐Dupré‐Christol basal cell carcinoma susceptibility syndrome
Y Liu, S Banka, Y Huang, J Hardman-Smart, D Pye, A Torrelo, ...
British Journal of Dermatology 187 (6), 948-961, 2022
P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells
E Hampson, E Tsonou, MJ Baker, DC Hornigold, RE Hubbard, A Massey, ...
Cells 10 (9), 2474, 2021
A TIAM1-TRIM28 complex mediates epigenetic silencing of protocadherins to promote migration of lung cancer cells
L Ginn, J Maltas, MJ Baker, A Chaturvedi, L Wilson, R Guilbert, ...
Proceedings of the National Academy of Sciences 120 (40), e2300489120, 2023
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