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Digambar kumar Waiker
Digambar kumar Waiker
DEPT. OF PHARM. ENG. & TECH. , INDIAN INSTITUTE OF TECHNOLOGY-BHU (IIT-BHU), Varanasi
Verified email at itbhu.ac.in
Title
Cited by
Cited by
Year
Human CDC2-like kinase 1 (CLK1): A novel target for Alzheimer’s disease
P Jain, C Karthikeyan, NS Hari Narayana Moorthy, D Kumar Waiker, ...
Current drug targets 15 (5), 539-550, 2014
972014
Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s disease
SK Shrivastava, SK Sinha, P Srivastava, PN Tripathi, P Sharma, ...
Bioorganic chemistry 82, 211-223, 2019
532019
The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s disease
A Verma, DK Waiker, B Bhardwaj, P Saraf, SK Shrivastava
Bioorganic Chemistry 119, 105562, 2022
352022
Synthesis, biological evaluation and molecular modelling studies of 4-anilinoquinazoline derivatives as protein kinase inhibitors
DK Waiker, C Karthikeyan, V Poongavanam, J Kongsted, O Lozach, ...
Bioorganic & Medicinal Chemistry 22 (6), 1909-1915, 2014
202014
Design, synthesis, and evaluation of some novel biphenyl imidazole derivatives for the treatment of Alzheimer's disease
SP Ramrao, A Verma, DK Waiker, PN Tripathi, SK Shrivastava
Journal of Molecular Structure 1246, 131152, 2021
152021
N-(1H-Pyrazol-3-yl) quinazolin-4-amines as a novel class of casein kinase 1δ/ε inhibitors: Synthesis, biological evaluation and molecular modeling studies
C Karthikeyan, P Jharia, DK Waiker, AC Nusbaum, H Amawi, EM Kirwen, ...
Bioorganic & Medicinal Chemistry Letters 27 (12), 2663-2667, 2017
142017
Proteolysis-Resistant Self-Assembled ω -Amino Acid Dipeptide-Based Biocompatible Hydrogels as Drug Delivery Vehicle
ADK Priyanka Tiwari, Ritu Verma, Anindya Basu, Ryann M. Christman, Amit K ...
ChemistrySelect 2 ((23)), 6623-6631, 2017
122017
Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands …
DK Waiker, A Verma, Akhilesh, N Singh, A Roy, H Dilnashin, V Tiwari, ...
ACS Chemical Neuroscience 14 (11), 2217-2242, 2023
102023
Design and development of benzyl piperazine linked 5-phenyl-1, 2, 4-triazole-3-thione conjugates as potential agents to combat Alzheimer’s disease
PVR Kiran, DK Waiker, A Verma, P Saraf, B Bhardwaj, H Kumar, A Singh, ...
Bioorganic Chemistry 139, 106749, 2023
82023
Novel 5, 6-diphenyl-1, 2, 4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity
P Saraf, PN Tripathi, MK Tripathi, A Tripathi, H Verma, DK Waiker, ...
Bioorganic Chemistry 129, 106147, 2022
82022
Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease
SK Shrivastava, AA Nivrutti, B Bhardwaj, DK Waiker, A Verma, PN Tripathi, ...
Journal of Molecular Structure 1262, 132979, 2022
82022
Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat …
DK Waiker, A Verma, P Saraf, G TA, S Krishnamurthy, RN Chaurasia, ...
ACS omega 8 (10), 9394-9414, 2023
62023
Discovery of novel dual acetylcholinesterase and butyrylcholinesterase inhibitors using machine learning and structure-based drug design
MK Tripathi, B Bhardwaj, DK Waiker, A Tripathi, SK Shrivastava
Journal of Molecular Structure 1286, 135517, 2023
42023
Antiproliferative Efficacy of N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine, DW-8, in Colon Cancer Cells Is Mediated by Intrinsic Apoptosis
R Neupane, S Malla, MS Abou-Dahech, S Balaji, S Kumari, DK Waiker, ...
Molecules 26 (15), 4417, 2021
42021
Design, Synthesis, and Biological Investigation of Quinazoline Derivatives as Multitargeting Therapeutics in Alzheimer’s Disease Therapy
A Verma, DK Waiker, N Singh, A Roy, N Singh, P Saraf, B Bhardwaj, ...
ACS Chemical Neuroscience, 2024
12024
Synthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitors
SK Shrivastava, O Sinha, M Kumar, DK Waiker, A Verma, PN Tripathi, ...
Medicinal Chemistry Research 31 (9), 1594-1610, 2022
12022
Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer’s disease treatment
A Verma, DK Waiker, N Singh, A Singh, P Saraf, B Bhardwaj, P Kumar, ...
European Journal of Medicinal Chemistry, 116450, 2024
2024
Design, Synthesis, and Biological Evaluation of Some 2-(3-oxo-5, 6-diphenyl-1, 2, 4-triazin-2 (3H)-yl)-N-phenylacetamide Hybrids as MTDLs for Alzheimer’s Disease Therapy
DK Waiker, A Verma, TA Gajendra, A Roy, P Kumar, SK Trigun, ...
European Journal of Medicinal Chemistry, 116409, 2024
2024
Structure-Guided Design, Synthesis, and Biological Evaluation of Peripheral Anionic Site Selective and Brain Permeable Novel Oxadiazole-Piperazine Conjugates against Alzheimer …
A Singh, A Verma, B Bhardwaj, P Saraf, H Kumar, N Jain, DK Waiker, ...
ACS omega, 2024
2024
Design, Synthesis, and Biological Evaluation of Some Heterocyclic Multifunctional Molecular Hybrids for Alzheimer’s disease Therapy
DK Waiker
IIT (BHU) Varanasi, 2023
2023
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