Human CDC2-like kinase 1 (CLK1): A novel target for Alzheimer’s disease P Jain, C Karthikeyan, NS Hari Narayana Moorthy, D Kumar Waiker, ... Current drug targets 15 (5), 539-550, 2014 | 97 | 2014 |
Design and development of novel p-aminobenzoic acid derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer’s disease SK Shrivastava, SK Sinha, P Srivastava, PN Tripathi, P Sharma, ... Bioorganic chemistry 82, 211-223, 2019 | 53 | 2019 |
The molecular mechanism, targets, and novel molecules in the treatment of Alzheimer’s disease A Verma, DK Waiker, B Bhardwaj, P Saraf, SK Shrivastava Bioorganic Chemistry 119, 105562, 2022 | 35 | 2022 |
Synthesis, biological evaluation and molecular modelling studies of 4-anilinoquinazoline derivatives as protein kinase inhibitors DK Waiker, C Karthikeyan, V Poongavanam, J Kongsted, O Lozach, ... Bioorganic & Medicinal Chemistry 22 (6), 1909-1915, 2014 | 20 | 2014 |
Design, synthesis, and evaluation of some novel biphenyl imidazole derivatives for the treatment of Alzheimer's disease SP Ramrao, A Verma, DK Waiker, PN Tripathi, SK Shrivastava Journal of Molecular Structure 1246, 131152, 2021 | 15 | 2021 |
N-(1H-Pyrazol-3-yl) quinazolin-4-amines as a novel class of casein kinase 1δ/ε inhibitors: Synthesis, biological evaluation and molecular modeling studies C Karthikeyan, P Jharia, DK Waiker, AC Nusbaum, H Amawi, EM Kirwen, ... Bioorganic & Medicinal Chemistry Letters 27 (12), 2663-2667, 2017 | 14 | 2017 |
Proteolysis-Resistant Self-Assembled ω -Amino Acid Dipeptide-Based Biocompatible Hydrogels as Drug Delivery Vehicle ADK Priyanka Tiwari, Ritu Verma, Anindya Basu, Ryann M. Christman, Amit K ... ChemistrySelect 2 ((23)), 6623-6631, 2017 | 12 | 2017 |
Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands … DK Waiker, A Verma, Akhilesh, N Singh, A Roy, H Dilnashin, V Tiwari, ... ACS Chemical Neuroscience 14 (11), 2217-2242, 2023 | 10 | 2023 |
Design and development of benzyl piperazine linked 5-phenyl-1, 2, 4-triazole-3-thione conjugates as potential agents to combat Alzheimer’s disease PVR Kiran, DK Waiker, A Verma, P Saraf, B Bhardwaj, H Kumar, A Singh, ... Bioorganic Chemistry 139, 106749, 2023 | 8 | 2023 |
Novel 5, 6-diphenyl-1, 2, 4-triazine-3-thiol derivatives as dual COX-2/5-LOX inhibitors devoid of cardiotoxicity P Saraf, PN Tripathi, MK Tripathi, A Tripathi, H Verma, DK Waiker, ... Bioorganic Chemistry 129, 106147, 2022 | 8 | 2022 |
Drug reposition-based design, synthesis, and biological evaluation of dual inhibitors of acetylcholinesterase and β-Secretase for treatment of Alzheimer's disease SK Shrivastava, AA Nivrutti, B Bhardwaj, DK Waiker, A Verma, PN Tripathi, ... Journal of Molecular Structure 1262, 132979, 2022 | 8 | 2022 |
Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat … DK Waiker, A Verma, P Saraf, G TA, S Krishnamurthy, RN Chaurasia, ... ACS omega 8 (10), 9394-9414, 2023 | 6 | 2023 |
Discovery of novel dual acetylcholinesterase and butyrylcholinesterase inhibitors using machine learning and structure-based drug design MK Tripathi, B Bhardwaj, DK Waiker, A Tripathi, SK Shrivastava Journal of Molecular Structure 1286, 135517, 2023 | 4 | 2023 |
Antiproliferative Efficacy of N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine, DW-8, in Colon Cancer Cells Is Mediated by Intrinsic Apoptosis R Neupane, S Malla, MS Abou-Dahech, S Balaji, S Kumari, DK Waiker, ... Molecules 26 (15), 4417, 2021 | 4 | 2021 |
Design, Synthesis, and Biological Investigation of Quinazoline Derivatives as Multitargeting Therapeutics in Alzheimer’s Disease Therapy A Verma, DK Waiker, N Singh, A Roy, N Singh, P Saraf, B Bhardwaj, ... ACS Chemical Neuroscience, 2024 | 1 | 2024 |
Synthesis, characterization, and biological evaluation of some novel ϒ-aminobutyric acid aminotransferase (GABA-AT) inhibitors SK Shrivastava, O Sinha, M Kumar, DK Waiker, A Verma, PN Tripathi, ... Medicinal Chemistry Research 31 (9), 1594-1610, 2022 | 1 | 2022 |
Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer’s disease treatment A Verma, DK Waiker, N Singh, A Singh, P Saraf, B Bhardwaj, P Kumar, ... European Journal of Medicinal Chemistry, 116450, 2024 | | 2024 |
Design, Synthesis, and Biological Evaluation of Some 2-(3-oxo-5, 6-diphenyl-1, 2, 4-triazin-2 (3H)-yl)-N-phenylacetamide Hybrids as MTDLs for Alzheimer’s Disease Therapy DK Waiker, A Verma, TA Gajendra, A Roy, P Kumar, SK Trigun, ... European Journal of Medicinal Chemistry, 116409, 2024 | | 2024 |
Structure-Guided Design, Synthesis, and Biological Evaluation of Peripheral Anionic Site Selective and Brain Permeable Novel Oxadiazole-Piperazine Conjugates against Alzheimer … A Singh, A Verma, B Bhardwaj, P Saraf, H Kumar, N Jain, DK Waiker, ... ACS omega, 2024 | | 2024 |
Design, Synthesis, and Biological Evaluation of Some Heterocyclic Multifunctional Molecular Hybrids for Alzheimer’s disease Therapy DK Waiker IIT (BHU) Varanasi, 2023 | | 2023 |