Filippo Minutolo
Filippo Minutolo
UniversitÓ di Pisa (IT), Dipartimento di Farmacia
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Estrogen receptors alpha (ERα) and beta (ERβ): subtype-selective ligands and clinical potential
I Paterni, C Granchi, JA Katzenellenbogen, F Minutolo
Steroids 90, 13-29, 2014
Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy
F Rossari, F Minutolo, E Orciuolo
Journal of hematology & oncology 11, 1-14, 2018
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials
C Granchi, S Bertini, M Macchia, F Minutolo
Current medicinal chemistry 17 (7), 672-697, 2010
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells
C Granchi, S Roy, C Giacomelli, M Macchia, T Tuccinardi, A Martinelli, ...
Journal of medicinal chemistry 54 (6), 1599-1612, 2011
Heterogeneous asymmetric epoxidation of unfunctionalized olefins catalyzed by polymer-bound (salen) manganese complexes
F Minutolo, D Pini, A Petri, P Salvadori
Tetrahedron: Asymmetry 7 (8), 2293-2302, 1996
Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies
M Apicella, E Giannoni, S Fiore, KJ Ferrari, D Fernßndez-PÚrez, C Isella, ...
Cell metabolism 28 (6), 848-865. e6, 2018
Anticancer agents that counteract tumor glycolysis
C Granchi, F Minutolo
ChemMedChem 7 (8), 1318-1350, 2012
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia
M Maftouh, A Avan, R Sciarrillo, C Granchi, LG Leon, R Rani, N Funel, ...
British journal of cancer 110 (1), 172-182, 2014
Polymer-bound chiral (salen) Mn (III) complex as heterogeneous catalyst in rapid and clean enantioselective epoxidation of unfunctionalised olefins
F Minutolo, D Pini, P Salvadori
Tetrahedron Letters 37 (19), 3375-3378, 1996
Estrogen receptor β ligands: recent advances and biomedical applications
F Minutolo, M Macchia, BS Katzenellenbogen, JA Katzenellenbogen
Medicinal research reviews 31 (3), 364-442, 2011
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD (H)-dependent and (ii) p53-independent pathways
SJ Allison, JRP Knight, C Granchi, R Rani, F Minutolo, J Milner, ...
Oncogenesis 3 (5), e102-e102, 2014
An update on therapeutic opportunities offered by cancer glycolytic metabolism
C Granchi, D Fancelli, F Minutolo
Bioorganic & medicinal chemistry letters 24 (21), 4915-4925, 2014
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2)
A Rossello, E Nuti, E Orlandini, P Carelli, S Rapposelli, M Macchia, ...
Bioorganic & medicinal chemistry 12 (9), 2441-2450, 2004
Heparin in COVID-19 patients is associated with reduced in-hospital mortality: the multicenter Italian CORIST study
A Di Castelnuovo, S Costanzo, A Antinori, N Berselli, L Blandi, ...
Thrombosis and haemostasis 121 (08), 1054-1065, 2021
Synthesis of a resveratrol analogue with high ceramide-mediated proapoptotic activity on human breast cancer cells
F Minutolo, G Sala, A Bagnacani, S Bertini, I Carboni, G Placanica, ...
Journal of medicinal chemistry 48 (22), 6783-6786, 2005
Small-molecule inhibitors of human LDH5
C Granchi, I Paterni, R Rani, F Minutolo
Future medicinal chemistry 5 (16), 1967-1991, 2013
Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study
A Di Castelnuovo, S Costanzo, A Antinori, N Berselli, L Blandi, R Bruno, ...
European Journal of Internal Medicine 82, 38-47, 2020
Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer
D Massihnia, A Avan, N Funel, M Maftouh, A Van Krieken, C Granchi, ...
Journal of Hematology & Oncology 10, 1-17, 2017
The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: interplay with the complex tumor microenvironment and novel therapeutic strategies
B El Hassouni, C Granchi, A VallÚs-MartÝ, IGP Supadmanaba, G Bononi, ...
Seminars in cancer biology 60, 238-248, 2020
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death
S Daniele, C Giacomelli, E Zappelli, C Granchi, ML Trincavelli, F Minutolo, ...
Scientific reports 5 (1), 15556, 2015
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