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Prajish Iyer
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NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome
P Chandrani, V Kulkarni, P Iyer, P Upadhyay, R Chaubal, P Das, ...
British journal of cancer 112 (12), 1958-1965, 2015
722015
Non-typhoidal Salmonella DNA traces in gallbladder cancer
P Iyer, SG Barreto, B Sahoo, P Chandrani, MR Ramadwar, ...
Infectious agents and cancer 11, 1-4, 2016
562016
ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer
P Iyer, SV Shrikhande, M Ranjan, A Joshi, N Gardi, R Prasad, ...
International journal of cancer 144 (8), 2008-2019, 2019
442019
Drug-sensitiveFGFR3 mutations in lung adenocarcinoma
P Chandrani, K Prabhash, R Prasad, V Sethunath, M Ranjan, P Iyer, ...
Annals of oncology 28 (3), 597-603, 2017
412017
Coexistence of KRAS mutation with mutant but not wild-type EGFR predicts response to tyrosine-kinase inhibitors in human lung cancer
A Choughule, R Sharma, V Trivedi, A Thavamani, V Noronha, A Joshi, ...
British journal of cancer 111 (11), 2203-2204, 2014
412014
Inhibition of SETMAR–H3K36me2–NHEJ repair axis in residual disease cells prevents glioblastoma recurrence
E Kaur, J Nair, A Ghorai, SV Mishra, A Achareker, M Ketkar, D Sarkar, ...
Neuro-oncology 22 (12), 1785-1796, 2020
222020
Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations
A Joshi, R Mishra, S Desai, P Chandrani, H Kore, R Sunder, S Hait, P Iyer, ...
Oncotarget 12 (6), 578, 2021
162021
TMC-SNPdb: an Indian germline variant database derived from whole exome sequences
P Upadhyay, N Gardi, S Desai, B Sahoo, A Singh, T Togar, P Iyer, ...
Database 2016, 2016
122016
Integrated genomics approach to identify biologically relevant alterations in fewer samples
P Chandrani, P Upadhyay, P Iyer, M Tanna, M Shetty, GV Raghuram, ...
BMC genomics 16, 1-13, 2015
112015
SF3B1 mutation and ATM deletion codrive leukemogenesis via centromeric R-loop dysregulation
M Cusan, H Shen, B Zhang, A Liao, L Yang, M Jin, M Fernandez, P Iyer, ...
The Journal of clinical investigation 133 (17), 2023
62023
Emerging therapies in CLL in the era of precision medicine
P Iyer, L Wang
Cancers 15 (5), 1583, 2023
62023
Expression of Sf3b1-K700E accelerates the development of chronic lymphocytic leukemia in a del (13q) murine model
B Zhang, P Iyer, M Jin, E Ten Hacken, Z Cartun, K Hart, LZ Rassenti, ...
Blood 136, 4-5, 2020
52020
MGA deletion leads to Richter’s transformation via modulation of mitochondrial OXPHOS
P Iyer, B Zhang, T Liu, M Jin, K Hart, J Zhang, J Song, WC Chan, T Siddiqi, ...
bioRxiv, 2023.02. 07.527502, 2023
12023
Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches
P Iyer, B Zhang, T Liu, M Jin, K Hart, JY Song, WC Chan, T Siddiqi, ...
Blood 140 (Supplement 1), 9842-9843, 2022
12022
MGA deletion leads to Richter's transformation via NME1
P Iyer, B Zhang, T Liu, M Jin, K Hart, JY Song, J Chan, R Pillai, T Siddiqi, ...
Blood 138, 252, 2021
12021
Glycerolipid Metabolism Via the MGA-MYC-NME1-PGP Axis As a Key Regulator of Oxidative Phosphorylation in Richter's Transformation
P Iyer, B Jiang, G Venkataraman, JY Song, T Siddiqi, ST Rosen, ...
Blood 142, 79, 2023
2023
Beyond CLL Progression: Unveiling Th17 and Th2 T Cell Subsets As Predictors of Pembrolizumab Response in Richter's Transformation
P Iyer, L Yang, S Sinha, M Del Busso, ZZ Yang, H Kim, C Secreto, Y Wang, ...
Blood 142, 1888, 2023
2023
Unveiling ATF6 and PPM1H signaling in hepatocellular carcinoma progression: From ER stress to tumor suppression
P Iyer, S Oberai, B Jiang, D Marimekala
Molecular Therapy-Nucleic Acids 33, 813-815, 2023
2023
R-Loop Associated Mitotic Stress Confers Vulnerabilities in Splicing Factor Mutant Leukemia
M Cusan, M Jin, B Zhang, M Fernandez, A Liao, L Yang, Y Wu, P Iyer, ...
Blood 138, 3713, 2021
2021
Tumor intrinsic changes determine immune-checkpoint response in Richter's transformation
PS Iyer, L Yang, YZ Zhang, HJ Kim, C Secreto, S Sinha, N Kay, S Ansell, ...
Cancer Research 81 (13_Supplement), 1612-1612, 2021
2021
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