Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors DR Gorja, S Mukherjee, CLT Meda, GS Deora, KL Kumar, A Jain, ... Organic & Biomolecular Chemistry 11 (13), 2075-2079, 2013 | 71 | 2013 |
Regioselective construction of six-membered fused heterocyclic rings via Pd/C-mediated C–C coupling followed by iodocyclization strategy: a new entry to 2H-1, 2-benzothiazine-1 … DK Barange, VR Batchu, D Gorja, VR Pattabiraman, LK Tatini, JM Babu, ... Tetrahedron 63 (8), 1775-1789, 2007 | 57 | 2007 |
C–C bond formation at C-2 of a quinoline ring: Synthesis of 2-(1H-indol-3-yl) quinoline-3-carbonitrile derivatives as a new class of PDE4 inhibitors KS Kumar, SK Kumar, BY Sreenivas, DR Gorja, R Kapavarapu, ... Bioorganic & medicinal chemistry 20 (7), 2199-2207, 2012 | 32 | 2012 |
Aurora B kinase as a novel molecular target for inhibition the growth of osteosarcoma Z Zhao, G Jin, K Yao, K Liu, F Liu, H Chen, K Wang, DR Gorja, K Reddy, ... Molecular carcinogenesis 58 (6), 1056-1067, 2019 | 25 | 2019 |
Selective synthesis of 2, 5-disubstituted furan-3-carboxylates and the isomeric 2, 4-disubstituted furan-3-carboxylates P Chen, Y Meng, Q Yang, J Wu, Y Xiao, DR Gorja, C Song, J Chang RSC advances 5 (97), 79906-79914, 2015 | 19 | 2015 |
Zebrafish based strategy for the identification of a potential pharmacophore for apoptosis: a greener CuAAC approach for novel 1, 2, 3-triazoles derived from mefenamic acid PV Babu, S Mukherjee, DR Gorja, S Yellanki, R Medisetti, P Kulkarni, ... RSC Advances 4 (10), 4878-4882, 2014 | 18 | 2014 |
Design and synthesis of 4-alkynyl pyrazoles as inhibitors of PDE4: A practical access via Pd/C–Cu catalysis DR Gorja, KS Kumar, A Kandale, CLT Meda, KVL Parsa, K Mukkanti, ... Bioorganic & medicinal chemistry letters 22 (7), 2480-2487, 2012 | 18 | 2012 |
C–C (alkynylation) vs C–O (ether) bond formation under Pd/C–Cu catalysis: synthesis and pharmacological evaluation of 4-alkynylthieno [2, 3-d] pyrimidines DR Gorja, KS Kumar, K Mukkanti, M Pal Beilstein journal of organic chemistry 7 (1), 338-345, 2011 | 18 | 2011 |
Pd/C-mediated synthesis of α-pyrone fused with a five-membered nitrogen heteroaryl ring: A new route to pyrano [4, 3-c] pyrazol-4 (1H)-ones DR Gorja, VR Batchu, A Ettam, M Pal Beilstein Journal of Organic Chemistry 5 (1), 64, 2009 | 16 | 2009 |
Discovery of a novel dual-target inhibitor against RSK1 and MSK2 to suppress growth of human colon cancer G Jin, M Yan, K Liu, K Yao, H Chen, C Zhang, Y Yi, K Reddy, DR Gorja, ... Oncogene 39 (43), 6733-6746, 2020 | 10 | 2020 |
APIO-EE-9 is a novel Aurora A and B antagonist that suppresses esophageal cancer growth in a PDX mouse model G Jin, K Yao, Z Guo, Z Zhao, K Liu, F Liu, H Chen, DR Gorja, K Reddy, ... Oncotarget 8 (32), 53387, 2017 | 9 | 2017 |
The solution structure of human calcium-bound S100A4 mutated at four cysteine loci CC Cho, KW Hung, DR Gorja, C Yu Journal of biomolecular NMR 62, 233-238, 2015 | 7 | 2015 |
Pd/C‐Mediated Alkynylation of Indazoles: Synthesis and Pharmacological Evaluation of Mono and Dialkynyl‐Substituted Indazoles DR Gorja, K Shiva Kumar, B Dulla, K Mukkanti, M Pal Journal of Heterocyclic Chemistry 51 (2), 374-382, 2014 | 7 | 2014 |
Novel dual inhibitor for targeting PIM1 and FGFR1 kinases inhibits colorectal cancer growth in vitro and patient-derived xenografts in vivo F Yin, R Zhao, DR Gorja, X Fu, N Lu, H Huang, B Xu, H Chen, JH Shim, ... Acta Pharmaceutica Sinica B 12 (11), 4122-4137, 2022 | 6 | 2022 |
Synthesis of N-(3-arylprop-2-ynyl) substituted olanzapine derivatives as potential inhibitors of PDE4B PV Babu, DR Gorja, CLT Meda, GS Deora, SK Kolli, KVL Parsa, ... Tetrahedron letters 55 (20), 3176-3180, 2014 | 5 | 2014 |
In Silico and Biological Evaluation of N‐(2‐methoxyphenyl) Substituted Pyrazoles Accessed via a Sonochemical Method M Venkata Basaveswara Rao, B Veera Durga Rao, S Vijaya Vardhini, ... ChemistrySelect 6 (4), 788-797, 2021 | 4 | 2021 |
Aurora B Kinase as a Novel Molecular Approach for Osteosarcoma Therapy Z Zhao, G Jin, K Yao, K Liu, F Liu, H Chen, K Wang, DR Gorja, K Reddy, ... Available at SSRN 3263641, 2018 | | 2018 |
Pd/C-Mediated. DR Gorja, K Shiva Kumar, B Dulla, K Mukkanti, M Pal Journal of Heterocyclic Chemistry 51 (2), 2014 | | 2014 |
Synthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles DR Gorja Kukatpally, 2012 | | 2012 |
Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo [1, 2-a] pyridines and isomeric … KS Kumar, SK Kumar, BY Sreenivas, DR Gorja, R Kapavarapu, ... Bioorganic & Medicinal Chemistry 20 (7), 2191-2198, 2012 | | 2012 |