| Molecular tension sensors report forces generated by single integrin molecules in living cells M Morimatsu, AH Mekhdjian, AS Adhikari, AR Dunn Nano letters 13 (9), 3985-3989, 2013 | 243 | 2013 |
| The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations S Nag, DV Trivedi, SS Sarkar, AS Adhikari, MS Sunitha, S Sutton, ... Nature structural & molecular biology 24 (6), 525-533, 2017 | 192 | 2017 |
| Mechanical load induces a 100-fold increase in the rate of collagen proteolysis by MMP-1 AS Adhikari, J Chai, AR Dunn Biophysical Journal 100 (3), 513a, 2011 | 142 | 2011 |
| Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light DV Trivedi, AS Adhikari, SS Sarkar, KM Ruppel, JA Spudich Biophysical reviews 10 (1), 27-48, 2018 | 138 | 2018 |
| Early-onset hypertrophic cardiomyopathy mutations significantly increase the velocity, force, and actin-activated ATPase activity of human β-cardiac myosin AS Adhikari, KB Kooiker, SS Sarkar, C Liu, D Bernstein, JA Spudich, ... Cell reports 17 (11), 2857-2864, 2016 | 87 | 2016 |
| A cytoskeletal clutch mediates cellular force transmission in a soft, three-dimensional extracellular matrix LM Owen, AS Adhikari, M Patel, P Grimmer, N Leijnse, MC Kim, ... Molecular biology of the cell 28 (14), 1959-1974, 2017 | 86 | 2017 |
| Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin JA Spudich, T Aksel, SR Bartholomew, S Nag, M Kawana, EC Yu, ... Journal of Experimental Biology 219 (2), 161-167, 2016 | 77 | 2016 |
| Mechanical coordination in motor ensembles revealed using engineered artificial myosin filaments RF Hariadi, RF Sommese, AS Adhikari, RE Taylor, S Sutton, JA Spudich, ... Nature nanotechnology 10 (8), 696-700, 2015 | 74 | 2015 |
| The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin SS Sarkar, DV Trivedi, MM Morck, AS Adhikari, SN Pasha, KM Ruppel, ... Science advances 6 (14), eaax0069, 2020 | 71 | 2020 |
| β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity AS Adhikari, DV Trivedi, SS Sarkar, D Song, KB Kooiker, D Bernstein, ... Nature communications 10 (1), 1-10, 2019 | 67 | 2019 |
| Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases AS Adhikari, E Glassey, AR Dunn Journal of the American Chemical Society 134 (32), 13259-13265, 2012 | 60 | 2012 |
| Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties CD Vera, CA Johnson, J Walklate, A Adhikari, M Svicevic, SM Mijailovich, ... Journal of Biological Chemistry 294 (46), 17451-17462, 2019 | 30 | 2019 |
| Strain tunes proteolytic degradation and diffusive transport in fibrin networks A Adhikari, A Mekhdjian, A Dunn Biophysical Journal 102 (3), 274a, 2012 | 28 | 2012 |
| pH-dependent formation of lipid heterogeneities controls surface topography and binding reactivity in functionalized bilayers GB Kempegowda, S Karve, A Bandekar, A Adhikari, T Khaimchayev, ... Langmuir 25 (14), 8144-8151, 2009 | 28 | 2009 |
| Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models JJ Metzger, C Pereda, A Adhikari, T Haremaki, S Galgoczi, ED Siggia, ... Cell Reports Methods 2 (9), 2022 | 10 | 2022 |
| Hypertrophic cardiomyopathy and the myosin mesa: viewing an old disease in a new light. Biophys Rev 10: 27–48 DV Trivedi, AS Adhikari, SS Sarkar, KM Ruppel, JA Spudich | 5 | 2018 |
| Multiplexed Single-molecule Force Proteolysis Measurements Using Magnetic Tweezers AS Adhikari, J Chai, AR Dunn Journal of Visualized Experiments 65 (e3520), 2012 | 5 | 2012 |
| The molecular basis of hypercontractility caused by the hypertrophic cardiomyopathy mutations R403Q and R663H SS Sarkar, DV Trivedi, MM Morck, AS Adhikari, SN Pasha, KM Ruppel, ... bioRxiv, 543413, 2019 | 4 | 2019 |
| Actomyosin Dynamics in 3D Traction Force Generation LM Owen, AS Adhikari, MC Kim, N Leijnse, AR Dunn Biophysical Journal 108 (2), 180a, 2015 | 1 | 2015 |
| β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity AS Adhikari, DV Trivedi, SS Sarkar, D Song, KB Kooiker, D Bernstein, ... Nature communications 10 (1), 1-10, 2019 | | 2019 |
James SpudichProfessor of Biochemistry, Stanford UniversityVerified email at stanford.edu
