| Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2 AL Eggler, G Liu, JM Pezzuto, RB Van Breemen, AD Mesecar Proceedings of the National Academy of Sciences 102 (29), 10070-10075, 2005 | 520 | 2005 |
| Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2 AL Eggler, KA Gay, AD Mesecar Molecular nutrition & food research 52 (S1), S84-S94, 2008 | 302 | 2008 |
| Modification of keap1 cysteine residues by sulforaphane C Hu, AL Eggler, AD Mesecar, RB Van Breemen Chemical research in toxicology 24 (4), 515-521, 2011 | 293 | 2011 |
| Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase BM Dietz, YH Kang, G Liu, AL Eggler, P Yao, LR Chadwick, GF Pauli, ... Chemical research in toxicology 18 (8), 1296-1305, 2005 | 285 | 2005 |
| Sites of alkylation of human Keap1 by natural chemoprevention agents Y Luo, AL Eggler, D Liu, G Liu, AD Mesecar, RB van Breemen Journal of the American Society for Mass Spectrometry 18, 2226-2232, 2007 | 218 | 2007 |
| Discovery, Synthesis, And Structure-Based Optimization of a Series of N-(tert-Butyl)-2-(N-arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent … J Jacobs, V Grum-Tokars, Y Zhou, M Turlington, SA Saldanha, P Chase, ... Journal of medicinal chemistry 56 (2), 534-546, 2013 | 207 | 2013 |
| Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1 AL Eggler, E Small, M Hannink, AD Mesecar Biochemical journal 422 (1), 171-180, 2009 | 189 | 2009 |
| The Rad51-dependent pairing of long DNA substrates is stabilized by replication protein A AL Eggler, RB Inman, MM Cox Journal of Biological Chemistry 277 (42), 39280-39288, 2002 | 141 | 2002 |
| Discovery of N-(benzo [1, 2, 3] triazol-1-yl)-N-(benzyl) acetamido) phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors … M Turlington, A Chun, S Tomar, A Eggler, V Grum-Tokars, J Jacobs, ... Bioorganic & medicinal chemistry letters 23 (22), 6172-6177, 2013 | 132 | 2013 |
| The C terminus of the Escherichia coli RecA protein modulates the DNA binding competition with single-stranded DNA-binding protein AL Eggler, SL Lusetti, MM Cox Journal of Biological Chemistry 278 (18), 16389-16396, 2003 | 125 | 2003 |
| Prospective type 1 and type 2 disulfides of Keap1 protein R Holland, AE Hawkins, AL Eggler, AD Mesecar, D Fabris, JC Fishbein Chemical research in toxicology 21 (10), 2051-2060, 2008 | 113 | 2008 |
| Identification of the highly reactive cysteine 151 in the chemopreventive agent-sensor Keap1 protein is method-dependent AL Eggler, Y Luo, RB Van Breemen, AD Mesecar Chemical research in toxicology 20 (12), 1878-1884, 2007 | 91 | 2007 |
| Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1 G Liu, AL Eggler, BM Dietz, AD Mesecar, JL Bolton, JM Pezzuto, ... Analytical chemistry 77 (19), 6407-6414, 2005 | 72 | 2005 |
| DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hydrolysis on the importance of not getting stuck KP Rice, AL Eggler, P Sung, MM Cox Journal of Biological Chemistry 276 (42), 38570-38581, 2001 | 66 | 2001 |
| Insecticidal activity of cyanohydrin and monoterpenoid compounds CJ Peterson, R Tsao, AL Eggler, JR Coats Molecules 5 (4), 648-654, 2000 | 58 | 2000 |
| Comparison of human Nrf2 antibodies: a tale of two proteins ZA Kemmerer, NR Ader, SS Mulroy, AL Eggler Toxicology letters 238 (2), 83-89, 2015 | 49 | 2015 |
| Chemical and biological mechanisms of phytochemical activation of Nrf2 and importance in disease prevention AL Eggler, SN Savinov 50 Years of Phytochemistry Research: Volume 43, 121-155, 2013 | 41 | 2013 |
| RecA mutants MM Cox, SL Lusetti, AL Eggler, N Haruta US Patent 7,176,007, 2007 | 30 | 2007 |
| Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols M Sauerland, R Mertes, C Morozzi, AL Eggler, LF Gamon, MJ Davies Free Radical Biology and Medicine 169, 1-11, 2021 | 27 | 2021 |
| Screening for natural chemoprevention agents that modify human Keap1 C Hu, D Nikolic, AL Eggler, AD Mesecar, RB Van Breemen Analytical biochemistry 421 (1), 108-114, 2012 | 24 | 2012 |
