| CRISPR-Cas9 gene editing for sickle cell disease and β-thalassemia H Frangoul, D Altshuler, MD Cappellini, YS Chen, J Domm, BK Eustace, ... New England Journal of Medicine 384 (3), 252-260, 2021 | 1246 | 2021 |
| Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. RC Bargou, F Emmerich, D Krappmann, K Bommert, MY Mapara, ... The Journal of clinical investigation 100 (12), 2961-2969, 1997 | 999 | 1997 |
| Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression RC Bargou, K Jürchott, C Wagener, S Bergmann, S Metzner, K Bommert, ... Nature medicine 3 (4), 447-450, 1997 | 593 | 1997 |
| Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results … P Armand, A Nagler, EA Weller, SM Devine, DE Avigan, YB Chen, ... Journal of clinical oncology 31 (33), 4199, 2013 | 553 | 2013 |
| Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance MY Mapara, M Sykes Journal of clinical oncology 22 (6), 1136-1151, 2004 | 436 | 2004 |
| High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells RC Bargou, C Leng, D Krappmann, F Emmerich, MY Mapara, K Bommert, ... | 421 | 1996 |
| Expression of the bcl‐2 gene family in normal and malignant breast tissue: Low bax‐α expression in tumor cells correlates with resistance towards apoptosis RC Bargou, PT Daniel, MY Mapara, K Bommert, C Wagener, B Kallinich, ... International journal of cancer 60 (6), 854-859, 1995 | 343 | 1995 |
| Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen–presenting cells MY Mapara, YM Kim, SP Wang, R Bronson, DH Sachs, M Sykes Blood, The Journal of the American Society of Hematology 100 (5), 1903-1909, 2002 | 298 | 2002 |
| Macrophage inflammatory protein 1-alpha (MIP-1α) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells S Lentzsch, M Gries, M Janz, R Bargou, B Dörken, MY Mapara Blood, The Journal of the American Society of Hematology 101 (9), 3568-3573, 2003 | 271 | 2003 |
| Time-intensified dexamethasone/cisplatin/cytarabine: an effective salvage therapy with low toxicity in patients with relapsed and refractory Hodgkin’s disease A Josting, C Rudolph, M Reiser, M Mapara, M Sieber, HH Kirchner, ... Annals of Oncology 13 (10), 1628-1635, 2002 | 271 | 2002 |
| Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in … RC Bargou, C Wagener, K Bommert, MY Mapara, PT Daniel, W Arnold, ... The Journal of clinical investigation 97 (11), 2651-2659, 1996 | 263 | 1996 |
| APO‐1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: correlation with bcl‐2 oncogene expression MY Mapara, R Bargou, C Zugck, H Döhner, F Ustaoglu, RR Jonker, ... European journal of immunology 23 (3), 702-708, 1993 | 232 | 1993 |
| Growth and differentiation of human stem cell factor/erythropoietin-dependent erythroid progenitor cells in vitro B Panzenböck, P Bartunek, MY Mapara, M Zenke Blood, The Journal of the American Society of Hematology 92 (10), 3658-3668, 1998 | 229 | 1998 |
| Anti-CD20-and B-cell receptor-mediated apoptosis: evidence for shared intracellular signaling pathways S Mathas, A Rickers, K Bommert, B Dörken, MY Mapara Cancer research 60 (24), 7170-7176, 2000 | 212 | 2000 |
| Cologne high-dose sequential chemotherapy in relapsed and refractory Hodgkin lymphoma: results of a large multicenter study of the German Hodgkin Lymphoma Study Group (GHSG) A Josting, C Rudolph, M Mapara, JP Glossmann, M Sieber, HH Kirchner, ... Annals of Oncology 16 (1), 116-123, 2005 | 191 | 2005 |
| Biologic and clinical efficacy of LentiGlobin for sickle cell disease J Kanter, MC Walters, L Krishnamurti, MY Mapara, JL Kwiatkowski, ... New England Journal of Medicine 386 (7), 617-628, 2022 | 188 | 2022 |
| Thalidomide derivative CC-4047 inhibits osteoclast formation by down-regulation of PU. 1 G Anderson, M Gries, N Kurihara, T Honjo, J Anderson, V Donnenberg, ... Blood 107 (8), 3098-3105, 2006 | 185 | 2006 |
| Induction of the death‐promoting gene bax‐α sensitizes cultured breast‐cancer cells to drug‐induced apoptosis C Wagener, RC Bargou, PT Daniel, K Bommert, MY Mapara, HD Royer, ... International journal of cancer 67 (1), 138-141, 1996 | 150 | 1996 |
| Vorinostat plus tacrolimus and mycophenolate to prevent graft-versus-host disease after related-donor reduced-intensity conditioning allogeneic haemopoietic stem-cell … SW Choi, T Braun, L Chang, JLM Ferrara, A Pawarode, JM Magenau, ... The lancet oncology 15 (1), 87-95, 2014 | 147 | 2014 |
| Combination of bendamustine, lenalidomide, and dexamethasone (BLD) in patients with relapsed or refractory multiple myeloma is feasible and highly effective: results of phase 1 … S Lentzsch, A O'Sullivan, RC Kennedy, M Abbas, L Dai, SL Pregja, S Burt, ... Blood, The Journal of the American Society of Hematology 119 (20), 4608-4613, 2012 | 145 | 2012 |
Alexis ThompsonProfessor Pediatrics, University of PennsylvaniaVerified email at chop.edu
