|Hedgehog pathway and smoothened inhibitors in cancer therapies|
KK Chahal, M Parle, R Abagyan
Anti-cancer drugs 29 (5), 387-401, 2018
|Pharmacokinetics of a Fixed-Dose Combination of Atorvastatin and Metformin Extended Release versus Concurrent Administration of Individual Formulations|
K Kandhwal, S Dey, S Nazarudheen, R Arora, S Reyar, NR Thudi, T Monif, ...
Clinical drug investigation 31 (12), 853-863, 2011
|The angiotensin receptor blocker losartan suppresses growth of pulmonary metastases via AT1R-independent inhibition of CCR2 signaling and monocyte recruitment|
DP Regan, JW Coy, KK Chahal, L Chow, JN Kurihara, AM Guth, ...
The Journal of Immunology 202 (10), 3087-3102, 2019
|Establishing bioequivalence of racemic venlafaxine formulations using stereoselective assay method: Is it necessary?|
K Kandhwal, S Dey, S Nazarudheen, S Reyar, S Mishra, NR Thudi, ...
Chirality 23 (10), 948-954, 2011
|Combining benefits of an adrenergic and a muscarinic blocker in a single formulation–A pharmacokinetic evaluation|
S Nazarudheen, S Dey, K Kandhwal, R Arora, S Reyar, AH Khuroo, ...
Regulatory Toxicology and Pharmacology 67 (2), 226-231, 2013
|Identification of Four Amoebicidal Nontoxic Compounds by a Molecular Docking Screen of Naegleria fowleri Sterol Δ8−Δ7-Isomerase and Phenotypic Assays|
D Shi, KK Chahal, P Oto, LF Nothias, A Debnath, JH McKerrow, ...
ACS infectious diseases 5 (12), 2029-2038, 2019
|Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastoma|
AR Chahal KK, Li J, Kufareva I, Parle M, Durden DL, Wechsler-Reya RJ, Chen CC
PLOS ONE 14 (9), e0214901, 2019
|Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again|
T Ngo, BP Wilkins, SS So, P Keov, KK Chahal, AM Finch, JLJ Coleman, ...
|Dynamic Structural Modeling Revealed That Nilotinib Inhibits Smoothened Signaling|
KK Chahal, J Li, I Kufareva, D Durden, RW Reya, R Abagyan, CC Chen
Neurosurgery 66 (Supplement_1), nyz310_806, 2019
|Multi-target pharmacology of kinase inhibitors, beneficial off-targets and allosteric sites|
R Abagyan, I Kufareva, K Chahal, D Shi
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019
|Dexamethasone and Fludrocortisone Inhibit Hedgehog Signaling in Embryonic Cells|
KK Chahal, M Parle, R Abagyan
ACS omega 3 (9), 12019-12025, 2018
|Orthosteric and allosteric antagonism of chemokine receptors: Structural insights into compound affinity and selectivity|
K Chahal, G Baker, Y Zheng, A Tebben, T Handel, I Kufareva
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
|Diphenolic Acid in Plastics Activates Smoothened Receptor|
K Kandhwal, I Kufareva, M Parle, R Abagyan
The FASEB Journal 30 (1_supplement), 697.3-697.3, 2016
|Computationally guided repurposing of approved, multi-targeted therapeutics for smoothened-dependent cancers|
K Kandhwal, M Parle, R Abagyan, I Kufareva
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016
|Bioavailability & Bioequivalence|
|Regulatory recommendations for clopidogrel: Focus on validation of a reliable bioanalytical method and its application to a bioequivalence study|
S Dey, K Kandhwal, S Nazarudheen, O Singh, SK Mukherjee, S Mishra, ...
Clinical Research and Regulatory Affairs 28 (4), 87-95, 2011