| The dynamic process of β2-adrenergic receptor activation R Nygaard, Y Zou, RO Dror, TJ Mildorf, DH Arlow, A Manglik, AC Pan, ... Cell 152 (3), 532-542, 2013 | 885 | 2013 |
| Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor MP Bokoch, Y Zou, SGF Rasmussen, CW Liu, R Nygaard, ... Nature 463 (7277), 108-112, 2010 | 584 | 2010 |
| Ligand binding and micro-switches in 7TM receptor structures R Nygaard, TM Frimurer, B Holst, MM Rosenkilde, TW Schwartz Trends in pharmacological sciences 30 (5), 249-259, 2009 | 436 | 2009 |
| A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors 2 B Holst, R Nygaard, L Valentin-Hansen, A Bach, MS Engelstoft, ... Journal of Biological Chemistry 285 (6), 3973-3985, 2010 | 170 | 2010 |
| Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism B Holst, J Mokrosinski, M Lang, E Brandt, R Nygaard, TM Frimurer, ... Journal of biological chemistry 282 (21), 15799-15811, 2007 | 91 | 2007 |
| The PP-Fold Solution Structure of Human Polypeptide YY and Human PYY3-36 As Determined by NMR, R Nygaard, S Nielbo, TW Schwartz, FM Poulsen Biochemistry 45 (27), 8350-8357, 2006 | 70 | 2006 |
| Cryo-electron microscopy analysis of small membrane proteins R Nygaard, J Kim, F Mancia Current opinion in structural biology 64, 26-33, 2020 | 67 | 2020 |
| Conserved water-mediated hydrogen bond network between TM-I,-II,-VI, and-VII in 7TM receptor activation R Nygaard, L Valentin-Hansen, J Mokrosinski, TM Frimurer, TW Schwartz Journal of biological chemistry 285 (25), 19625-19636, 2010 | 64 | 2010 |
| Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8 PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, ... Molecular pharmacology 72 (2), 327-340, 2007 | 56 | 2007 |
| Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III,-IV, and-VI MM Rosenkilde, MB Andersen, R Nygaard, TM Frimurer, TW Schwartz Molecular pharmacology 71 (3), 930-941, 2007 | 52 | 2007 |
| Spectral snapshots of bacterial cell-wall composition and the influence of antibiotics by whole-cell NMR R Nygaard, JAH Romaniuk, DM Rice, L Cegelski Biophysical journal 108 (6), 1380-1389, 2015 | 51 | 2015 |
| Structural basis of WLS/Evi-mediated Wnt transport and secretion R Nygaard, J Yu, J Kim, DR Ross, G Parisi, OB Clarke, DM Virshup, ... Cell 184 (1), 194-206. e14, 2021 | 50 | 2021 |
| The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor L Valentin-Hansen, M Groenen, R Nygaard, TM Frimurer, ND Holliday, ... Journal of Biological Chemistry 287 (38), 31973-31982, 2012 | 38 | 2012 |
| Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions TM Frimurer, F Mende, AS Graae, MS Engelstoft, KL Egerod, R Nygaard, ... Journal of Medicinal Chemistry 60 (3), 886-898, 2017 | 32 | 2017 |
| A human pleiotropic multiorgan condition caused by deficient Wnt secretion G Chai, E Szenker-Ravi, C Chung, Z Li, L Wang, M Khatoo, T Marshall, ... New England Journal of Medicine 385 (14), 1292-1301, 2021 | 26 | 2021 |
| Structural basis of lipopolysaccharide maturation by the O-antigen ligase KU Ashraf, R Nygaard, ON Vickery, SK Erramilli, CM Herrera, ... Nature 604 (7905), 371-376, 2022 | 24 | 2022 |
| Whole ribosome NMR: dipolar couplings and contributions to whole cells R Nygaard, JAH Romaniuk, DM Rice, L Cegelski The Journal of Physical Chemistry B 121 (40), 9331-9335, 2017 | 12 | 2017 |
| Structural basis of peptidoglycan synthesis by E. coli RodA-PBP2 complex R Nygaard, CLB Graham, M Belcher Dufrisne, JD Colburn, J Pepe, ... Nature Communications 14 (1), 5151, 2023 | 2 | 2023 |
| Hereditære bindevævssygdomme U Tarp, RH Nygaard, AL Frederiksen Reumatologi, 291-299, 2018 | 2 | 2018 |
| Conformational Changes in GPCR Surface and Core Probed by [13C]-Methyl NMR Spectroscopy MP Bokoch, R Nygaard, Y Zou, SGF Rasmussen, L Pardo, RS Prosser, ... Biophysical Journal 98 (3), 418a, 2010 | 2 | 2010 |
Brian KobilkaStanford UniversityVerified email at stanford.edu
