|Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration|
R Abu Khalaf, GA Sheikha, Y Bustanji, MO Taha
European journal of medicinal chemistry 45 (4), 1598-1617, 2010
|Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N‐Myristoyl Transferase Inhibitors Followed by In Silico Screening|
MO Taha, AM Qandil, T Al‐Haraznah, R Abu Khalaf, H Zalloum, ...
Chemical biology & drug design 78 (3), 391-407, 2011
|In Vivo Antihyperlipidemic Activity of a New Series of N‐(Benzoylphenyl) and N‐(Acetylphenyl)‐1‐benzofuran‐2‐carboxamides in Rats|
T Al‐Qirim, G Shattat, K Sweidan, W El‐Huneidi, GA Sheikha, ...
Archiv der Pharmazie 345 (5), 401-406, 2012
|Discovery of new β-D-glucosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening|
R Abu Khalaf, AM Abdula, MS Mubarak, MO Taha
Journal of molecular modeling 17 (3), 443-464, 2011
|Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)|
DA Sabbah, M Saada, R Abu Khalaf, S Bardaweel, K Sweidan, T Al-Qirim, ...
Bioorganic & medicinal chemistry letters 25 (16), 3120-3124, 2015
|Discovery of new β‐D‐galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening|
AM Abdula, R Abu Khalaf, MS Mubarak, MO Taha
Journal of computational chemistry 32 (3), 463-482, 2011
|Exploring natural products as a source for antidiabetic lead compounds and possible lead optimization|
R Abu Khalaf
Current topics in medicinal chemistry 16 (23), 2549-2561, 2016
|Design, synthesis, and biological evaluation of benzylamino-methanone based cholesteryl ester transfer protein inhibitors|
G Abu Sheikha, R Abu Khalaf, A Melhem, G Albadawi
Molecules 15 (8), 5721-5733, 2010
|Structure-Based Design: Synthesis, X-Ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential PI3Kα Inhibitors|
D Sabbah, B Hishmah, K Sweidan, S Bardaweel, M AlDamen, H Zhong, ...
Anti-Cancer Agents in Medicinal Chemistry 18 (2), 263-276, 2017
|Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents|
DA Sabbah, F Al-Tarawneh, WH Talib, K Sweidan, SK Bardaweel, ...
Medicinal Chemistry 14 (7), 695 - 708, 2018
|Tryptophan and thiosemicarbazide derivatives: design, synthesis, and biological evaluation as potential β-d-galactosidase and β-d-glucosidase inhibitors|
R Abu Khalaf, AM Abdula, MS Mubarak, MO Taha
Medicinal Chemistry Research 24 (6), 2529-2550, 2015
|Design, synthesis, and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors|
R Abu Khalaf, GA Sheikha, M Al-Sha’er, G Albadawi, M Taha
Medicinal Chemistry Research 21 (11), 3669-3680, 2012
|Molecular docking and pharmacophore modeling studies of fluorinated benzamides as potential CETP inhibitors|
R Abu Khalaf, S Al-Rawashdeh, D Sabbah, G Abu Sheikha
Medicinal Chemistry 13 (3), 239-253, 2017
|Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors|
R Abu Khalaf, GA Sheikha, M Al-Sha'er, M Taha
The open medicinal chemistry journal 7, 39-48, 2013
|CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping, and Synthesis|
Abu Khalaf R. Abd El-Aziz H, Sabbah D, Albadawi G, Abu Sheikha G
Letters in Drug Design & Discovery 14 (12), 1391-1400, 2017
|Synthesis and in vivo anti-hyperlipidemic activity of novel N-benzoylphenyl-2-furamide derivatives in Wistar rats|
S Hikmat, T Al-qirim, D Alkabbani, G Shattat, GA Sheikha, D Sabbah, ...
Tropical Journal of Pharmaceutical Research 16 (1), 193-201, 2017
|Pharmacophore modeling and molecular docking studies of acridines as potential DPP-IV inhibitors|
Abu Khalaf R, Jarekji Z, Al-Qirim T, Sabbah D,Shattat G
Canadian Journal of Chemistry 93 (7), 721-729, 2015
|Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents.|
DA Sabbah, AH Ibrahim, WH Talib, KM Alqaisi, K Sweidan, SK Bardaweel, ...
Medicinal chemistry (Shariqah (United Arab Emirates)), 2018
|Synthesis of Novel Benzimidazole-2-carboxamide Derivatives and in Vivo Antihyperlipidemic Activity Evaluation|
GA Sheikha, MM Bkhaitan, H Kalloush, L Hamadneh, R Abu Khalaf, ...
Chemical and Pharmaceutical Bulletin 66 (4), 423-426, 2018
|Isolation and Structure Elucidation of Bioactive Polyphenols|
R Abu Khalaf, A Alhusban, E Al-Shalabi, I Al-Sheikh, D Sabbah
Studies in Natural Product Chemistry (Bioactive Natural Products), 2018