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Reema Abu Khalaf
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Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration
R Abu Khalaf, GA Sheikha, Y Bustanji, MO Taha
European journal of medicinal chemistry 45 (4), 1598-1617, 2010
682010
Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)
DA Sabbah, M Saada, R Abu Khalaf, S Bardaweel, K Sweidan, T Al-Qirim, ...
Bioorganic & medicinal chemistry letters 25 (16), 3120-3124, 2015
392015
Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents
DA Sabbah, F Al-Tarawneh, WH Talib, K Sweidan, SK Bardaweel, ...
Medicinal Chemistry 14 (7), 695 - 708, 2018
252018
Discovery of New Antifungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N‐Myristoyl Transferase Inhibitors Followed by In Silico Screening
MO Taha, AM Qandil, T Al‐Haraznah, R Abu Khalaf, H Zalloum, ...
Chemical biology & drug design 78 (3), 391-407, 2011
252011
Design, synthesis, and biological evaluation of benzylamino-methanone based cholesteryl ester transfer protein inhibitors
GA Sheikha, R Abu Khalaf, A Melhem, G Albadawi
Molecules 15 (8), 5721-5733, 2010
252010
In Vivo Antihyperlipidemic Activity of a New Series of N‐(Benzoylphenyl) and N‐(Acetylphenyl)‐1‐benzofuran‐2‐carboxamides in Rats
T Al‐Qirim, G Shattat, K Sweidan, W El‐Huneidi, GA Sheikha, ...
Archiv der Pharmazie 345 (5), 401-406, 2012
232012
Exploring natural products as a source for antidiabetic lead compounds and possible lead optimization
R Abu Khalaf
Current Topics in Medicinal Chemistry 16 (23), 2549-2561, 2016
222016
Discovery of new β-D-glucosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening
R Abu Khalaf, AM Abdula, MS Mubarak, MO Taha
Journal of molecular modeling 17 (3), 443-464, 2011
212011
Discovery of new β‐D‐galactosidase inhibitors via pharmacophore modeling and QSAR analysis followed by in silico screening
AM Abdula, R Abu Khalaf, MS Mubarak, MO Taha
Journal of computational chemistry 32 (3), 463-482, 2011
202011
Structure-Based Design: Synthesis, X-Ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential PI3Kα Inhibitors
D Sabbah, B Hishmah, K Sweidan, S Bardaweel, M AlDamen, H Zhong, ...
Anti-Cancer Agents in Medicinal Chemistry 18 (2), 263-276, 2017
192017
Molecular docking and pharmacophore modeling studies of fluorinated benzamides as potential CETP inhibitors
R Abu Khalaf, S Al-Rawashdeh, D Sabbah, G Abu Sheikha
Medicinal Chemistry 13 (3), 239-253, 2017
182017
Design, synthesis, and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors
R Abu Khalaf, GA Sheikha, M Al-Sha’er, G Albadawi, M Taha
Medicinal Chemistry Research 21 (11), 3669-3680, 2012
162012
Tryptophan and thiosemicarbazide derivatives: design, synthesis, and biological evaluation as potential β-d-galactosidase and β-d-glucosidase inhibitors
R Abu Khalaf, AM Abdula, MS Mubarak, MO Taha
Medicinal Chemistry Research 24 (6), 2529-2550, 2015
122015
Pharmacophore modeling and molecular docking studies of acridines as potential DPP-IV inhibitors
R Abu Khalaf, Z Jarekji,T Al-Qirim, D Sabbah, G Shattat
Canadian Journal of Chemistry 93 (7), 721-729, 2015
122015
Synthesis, biological evaluation and molecular modeling study of substituted benzyl benzamides as CETP inhibitors
R Abu Khalaf, D Sabbah, E Al-Shalabi, S Bishtawi, G Albadawi, ...
Archiv der Pharmazie 350 (12), 1-14, 2017
112017
CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping, and Synthesis
R Abu Khalaf, H Abd El-Aziz, D Sabbah, G Albadawi, G Abu Sheikha
Letters in Drug Design & Discovery 14 (12), 1391-1400, 2017
112017
Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors
R Abu Khalaf, GA Sheikha, M Al-Sha'er, M Taha
The open medicinal chemistry journal 7, 39-48, 2013
112013
Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents.
DA Sabbah, AH Ibrahim, WH Talib, KM Alqaisi, K Sweidan, SK Bardaweel, ...
Medicinal chemistry (Shariqah (United Arab Emirates)) 15 (4), 417-429, 2019
102019
Isolation and Structure Elucidation of Bioactive Polyphenols
R Abu Khalaf, A Alhusban, E Al-Shalabi, I Al-Sheikh, D Sabbah
Studies in Natural Product Chemistry (Bioactive Natural Products) 63, 267-337, 2019
9*2019
Synthesis, Structural Characterization and Docking Studies of Sulfamoyl-Phenyl Acid Esters as Dipeptidyl Peptidase-IV Inhibitors
R Abu Khalaf, D Sabbah, E Al-Shalabi, I Al-Sheikh, G Albadawi, ...
Current Computer-Aided Drug Design 14 (2), 142-151, 2018
92018
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