Jean A. Bernatchez
Jean A. Bernatchez
Eurofins DiscoverX
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Title
Cited by
Cited by
Year
Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase NS5B
MH Powdrill, JA Bernatchez, M Götte
Viruses 2 (10), 2169-2195, 2010
932010
Kinase and Histone Deacetylase Hybrid Inhibitors for Cancer Therapy
Y Luan, J Li, JA Bernatchez, R Li
Journal of Medicinal Chemistry 62 (7), 3171-3183, 2019
412019
Cysteine proteases in protozoan parasites
JL Siqueira-Neto, A Debnath, LI McCall, JA Bernatchez, M Ndao, ...
PLoS Neglected Tropical Diseases 12 (8), e0006512, 2018
362018
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics
J Balzarini, K Das, JA Bernatchez, SE Martinez, M Ngure, S Keane, ...
Proceedings of the National Academy of Sciences 112 (11), 3475-3480, 2015
232015
Dynamics of hepatitis C virus (HCV) RNA-dependent RNA polymerase NS5B in complex with RNA
P Karam, MH Powdrill, HW Liu, C Vasquez, W Mah, J Bernatchez, M Götte, ...
Journal of Biological Chemistry 289 (20), 14399-14411, 2014
222014
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
SC Mack, I Singh, X Wang, R Hirsch, Q Wu, R Villagomez, JA Bernatchez, ...
Journal of Experimental Medicine 216 (5), 1071-1090, 2019
152019
Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer
M Ehteshami, M Nijhuis, JA Bernatchez, CJ Ablenas, S McCormick, ...
Journal of Biological Chemistry 288 (24), 17336-17346, 2013
152013
Mechanism of action of methotrexate against Zika virus
S Beck, Z Zhu, MF Oliveira, DM Smith, JN Rich, JA Bernatchez, ...
Viruses 11 (4), 338, 2019
142019
Mass spectrometry-based chemical cartography of a cardiac parasitic infection
LI McCall, JT Morton, JA Bernatchez, JL de Siqueira-Neto, R Knight, ...
Analytical chemistry 89 (19), 10414-10421, 2017
142017
Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis
Z Zhu, P Mesci, JA Bernatchez, RC Gimple, X Wang, ST Schafer, ...
Cell Stem Cell 26 (2), 187-204, 2020
132020
Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase
JA Bernatchez, R Paul, EP Tchesnokov, M Ngure, GL Beilhartz, ...
Journal of Biological Chemistry 290 (3), 1474-1484, 2015
122015
Drugs for the Treatment of Zika Virus Infection
JA Bernatchez, LT Tran, J Li, Y Luan, JL Siqueira-Neto, R Li
Journal of Medicinal Chemistry 63 (2), 470-489, 2020
112020
Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting Zika virus
JA Bernatchez, Z Yang, M Coste, J Li, S Beck, Y Liu, AE Clark, Z Zhu, LA ...
Antimicrobial Agents and Chemotherapy 62 (10), pii: e00725-18, 2018
112018
Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells
JA Bernatchez, M Coste, S Beck, GA Wells, LA Luna, AE Clark, Z Zhu, ...
Viruses 11 (4), 365, 2019
72019
Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors
B Singh, JA Bernatchez, LI McCall, CM Calvet, J Ackermann, JM Souza, ...
ACS Medicinal Chemistry Letters 11 (3), 249–257, 2020
52020
High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi
JA Bernatchez, E Chen, MV Hull, CW McNamara, JH McKerrow, ...
Microorganisms 8 (4), 472, 2020
42020
Nucleotide sugar pucker preference mitigates excision by HIV-1 RT
K Yamada, AS Wahba, JA Bernatchez, T Ilina, S Martínez-Montero, ...
ACS chemical biology 10 (9), 2024-2033, 2015
42015
Local Phenomena Shape Backyard Soil Metabolite Composition
TD Nguyen, M Lesani, I Forrest, Y Lan, DA Dean, QMR Gibaut, Y Guo, ...
Metabolites 10 (3), 86, 2020
32020
A common anti-cytomegalovirus drug, ganciclovir, inhibits HIV-1 replication in human tissues ex vivo
C Vanpouille, JA Bernatchez, A Lisco, A Arakelyan, E Saba, M Götte, ...
AIDS (London, England) 31 (11), 1519, 2017
22017
Peptidomimetic Vinyl Heterocycle Inhibitors of Cruzain Effect Anti-Trypanosomal Activity
BC Chenna, L Li, DM Mellott, X Zhai, JL Siqueira-Neto, CM Calvet Alvarez, ...
Journal of Medicinal Chemistry 63 (6), 3298–3316, 2020
12020
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