Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis P Rada, AI Rojo, N Evrard-Todeschi, NG Innamorato, A Cotte, T Jaworski, ... Molecular and cellular biology 32 (17), 3486-3499, 2012 | 219 | 2012 |
Cytochromes P450 catalyze both steps of the major pathway of clopidogrel bioactivation, whereas paraoxonase catalyzes the formation of a minor thiol metabolite isomer PM Dansette, J Rosi, G Bertho, D Mansuy Chemical research in toxicology 25 (2), 348-356, 2012 | 114 | 2012 |
The First Water‐Soluble Copper(I) Calix[6]arene Complex Presenting a Hydrophobic Ligand Binding Pocket: A Remarkable Model for Active Sites in Metalloenzymes Y Rondelez, G Bertho, O Reinaud Angewandte Chemie 114 (6), 1086-1088, 2002 | 95 | 2002 |
Metabolic oxidative cleavage of thioesters: evidence for the formation of sulfenic acid intermediates in the bioactivation of the antithrombotic prodrugs ticlopidine and … PM Dansette, J Libraire, G Bertho, D Mansuy Chemical research in toxicology 22 (2), 369-373, 2009 | 85 | 2009 |
Automatic clustering of docking poses in virtual screening process using self-organizing map G Bouvier, N Evrard-Todeschi, JP Girault, G Bertho Bioinformatics 26 (1), 53-60, 2010 | 74 | 2010 |
First evidence that cytochrome P450 may catalyze both S-oxidation and epoxidation of thiophene derivatives PM Dansette, G Bertho, D Mansuy Biochemical and biophysical research communications 338 (1), 450-455, 2005 | 71 | 2005 |
Identification and quantitative analysis of the phytoecdysteroids in Silene species (Caryophyllaceae) by high-performance liquid chromatography: novel ecdysteroids from S … Y Meng, P Whiting, L Zibareva, G Bertho, JP Girault, R Lafont, L Dinan Journal of Chromatography A 935 (1-2), 309-319, 2001 | 65 | 2001 |
NMR studies of the phosphorylation motif of the HIV-1 protein Vpu bound to the F-box protein β-TrCP G Coadou, J Gharbi-Benarous, S Megy, G Bertho, N Evrard-Todeschi, ... Biochemistry 42 (50), 14741-14751, 2003 | 56 | 2003 |
Paraoxonase-1 and clopidogrel efficacy PM Dansette, J Rosi, G Bertho, D Mansuy Nature medicine 17 (9), 1040, 2011 | 53 | 2011 |
Transferred nuclear Overhauser effect study of macrolide–ribosome interactions: correlation between antibiotic activities and bound conformations G Bertho, J Gharbi-Benarous, M Delaforge, JP Girault Bioorganic & medicinal chemistry 6 (2), 209-221, 1998 | 52 | 1998 |
Conformational analysis of ketolide, conformations of RU 004 in solution and bound to bacterial ribosomes G Bertho, J Gharbi-Benarous, M Delaforge, C Lang, A Parent, JP Girault Journal of medicinal chemistry 41 (18), 3373-3386, 1998 | 50 | 1998 |
Sheep prion protein synthetic peptide spanning helix 1 and β-strand 2 (residues 142–166) shows β-hairpin structure in solution SA Kozin, G Bertho, AK Mazur, H Rabesona, JP Girault, T Haertlé, ... Journal of Biological Chemistry 276 (49), 46364-46370, 2001 | 43 | 2001 |
New highly efficient aziridine-functionalized tridentate sulfinyl catalysts for enantioselective diethylzinc addition to carbonyl compounds S Leśniak, M Rachwalski, E Sznajder, P Kiełbasiński Tetrahedron: Asymmetry 20 (20), 2311-2314, 2009 | 42 | 2009 |
Solution conformation of methylated macrolide antibiotics roxithromycin and erythromycin using NMR and molecular modelling. Ribosome-bound conformation determined by TRNOE and … G Bertho, P Ladam, J Gharbi-Benarous, M Delaforge, JP Girault International journal of biological macromolecules 22 (2), 103-127, 1998 | 41 | 1998 |
Lincomycin and clindamycin conformations. A fragment shared by macrolides, ketolides and lincosamides determined from TRNOE ribosome-bound conformations L Verdier, G Bertho, J Gharbi-Benarous, JP Girault Bioorganic & medicinal chemistry 8 (6), 1225-1243, 2000 | 40 | 2000 |
Tryptophan Depletion and the Kinase GCN2 Mediate IFN-γ–Induced Autophagy S Fougeray, I Mami, G Bertho, P Beaune, E Thervet, N Pallet The Journal of Immunology 189 (6), 2954-2964, 2012 | 38 | 2012 |
Possible role of region 152–156 in the structural duality of a peptide fragment from sheep prion protein S Megy, G Bertho, SA Kozin, P Debey, G Hui Bon Hoa, JP Girault Protein science 13 (12), 3151-3160, 2004 | 35 | 2004 |
Synthesis and glycosidase inhibitory activity of enantiopure polyhydroxylated octahydroindoles and decahydroquinolines, analogs to castanospermine C Gravier-Pelletier, W Maton, G Bertho, Y Le Merrer Tetrahedron 59 (44), 8721-8730, 2003 | 34 | 2003 |
Oxidative and Reductive Metabolism of Tris(p-carboxyltetrathiaaryl)methyl Radicals by Liver Microsomes C Decroos, Y Li, G Bertho, Y Frapart, D Mansuy, JL Boucher Chemical research in toxicology 22 (7), 1342-1350, 2009 | 32 | 2009 |
STD and TRNOESY NMR studies on the conformation of the oncogenic protein β-catenin containing the phosphorylated motif DpSGXXpS bound to the β-TrCP protein S Megy, G Bertho, J Gharbi-Benarous, N Evrard-Todeschi, G Coadou, ... Journal of Biological Chemistry 280 (32), 29107-29116, 2005 | 32 | 2005 |