Ken J Ishii
Ken J Ishii
Institute of Medical Science, The University of Tokyo
Verified email at - Homepage
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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
H Kato, O Takeuchi, S Sato, M Yoneyama, M Yamamoto, K Matsui, ...
Nature 441 (7089), 101-105, 2006
IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction
T Kawai, K Takahashi, S Sato, C Coban, H Kumar, H Kato, KJ Ishii, ...
Nature immunology 6 (10), 981-988, 2005
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
T Kawai, S Sato, KJ Ishii, C Coban, H Hemmi, M Yamamoto, K Terai, ...
Nature immunology 5 (10), 1061-1068, 2004
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
KJ Ishii, C Coban, H Kato, K Takahashi, Y Torii, F Takeshita, H Ludwig, ...
Nature immunology 7 (1), 40-48, 2006
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
S Uematsu, K Fujimoto, MH Jang, BG Yang, YJ Jung, M Nishiyama, ...
Nature immunology 9 (7), 769-776, 2008
Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
T Saitoh, N Fujita, T Hayashi, K Takahara, T Satoh, H Lee, K Matsunaga, ...
Proceedings of the National Academy of Sciences 106 (49), 20842-20846, 2009
Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin
C Coban, KJ Ishii, T Kawai, H Hemmi, S Sato, S Uematsu, M Yamamoto, ...
The Journal of experimental medicine 201 (1), 19-25, 2005
Cutting edge: role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
F Takeshita, CA Leifer, I Gursel, KJ Ishii, S Takeshita, M Gursel, ...
The Journal of Immunology 167 (7), 3555-3558, 2001
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
KJ Ishii, T Kawagoe, S Koyama, K Matsui, H Kumar, T Kawai, S Uematsu, ...
Nature 451 (7179), 725-729, 2008
Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
D Verthelyi, KJ Ishii, M Gursel, F Takeshita, DM Klinman
The Journal of Immunology 166 (4), 2372-2377, 2001
The Atg5–Atg12 conjugate associates with innate antiviral immune responses
N Jounai, F Takeshita, K Kobiyama, A Sawano, A Miyawaki, KQ Xin, ...
Proceedings of the National Academy of Sciences 104 (35), 14050-14055, 2007
Host innate immune receptors and beyond: making sense of microbial infections
KJ Ishii, S Koyama, A Nakagawa, C Coban, S Akira
Cell host & microbe 3 (6), 352-363, 2008
Essential role of IPS-1 in innate immune responses against RNA viruses
H Kumar, T Kawai, H Kato, S Sato, K Takahashi, C Coban, M Yamamoto, ...
The Journal of experimental medicine 203 (7), 1795-1803, 2006
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR) 7-and TLR9-mediated interferon-α induction
S Uematsu, S Sato, M Yamamoto, T Hirotani, H Kato, F Takeshita, ...
The Journal of experimental medicine 201 (6), 915-923, 2005
DNA released from dying host cells mediates aluminum adjuvant activity
T Marichal, K Ohata, D Bedoret, C Mesnil, C Sabatel, K Kobiyama, ...
Nature medicine 17 (8), 996-1002, 2011
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c+ lamina propria cells
S Uematsu, MH Jang, N Chevrier, Z Guo, Y Kumagai, M Yamamoto, ...
Nature immunology 7 (8), 868-874, 2006
Innate immune response to viral infection
S Koyama, KJ Ishii, C Coban, S Akira
Cytokine 43 (3), 336-341, 2008
Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
CJ Desmet, KJ Ishii
Nature Reviews Immunology 12 (7), 479-491, 2012
DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
T Kondo, J Kobayashi, T Saitoh, K Maruyama, KJ Ishii, GN Barber, ...
Proceedings of the National Academy of Sciences 110 (8), 2969-2974, 2013
Differential role of TLR-and RLR-signaling in the immune responses to influenza A virus infection and vaccination
S Koyama, KJ Ishii, H Kumar, T Tanimoto, C Coban, S Uematsu, T Kawai, ...
The Journal of Immunology 179 (7), 4711-4720, 2007
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