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mitesh nagar
mitesh nagar
Post Doctoral Fellow
Verified email at umassmed.edu
Title
Cited by
Cited by
Year
The rheumatoid arthritis-associated citrullinome
R Tilvawala, SH Nguyen, AJ Maurais, VV Nemmara, M Nagar, ...
Cell chemical biology 25 (6), 691-704. e6, 2018
1792018
Development of a selective inhibitor of protein arginine deiminase 2
A Muth, V Subramanian, E Beaumont, M Nagar, P Kerry, P McEwan, ...
Journal of medicinal chemistry 60 (7), 3198-3211, 2017
722017
Calcium regulates the nuclear localization of protein arginine deiminase 2
L Zheng, M Nagar, AJ Maurais, DJ Slade, SS Parelkar, SA Coonrod, ...
Biochemistry 58 (27), 3042-3056, 2019
362019
Structure of mandelate racemase with bound intermediate analogues benzohydroxamate and cupferron
AD Lietzan, M Nagar, EA Pellmann, JR Bourque, SL Bearne, ...
Biochemistry 51 (6), 1160-1170, 2012
342012
Potent inhibition of mandelate racemase by a fluorinated substrate-product analogue with a novel binding mode
M Nagar, AD Lietzan, M St. Maurice, SL Bearne
Biochemistry 53 (7), 1169-1178, 2014
282014
Inhibition of serine and proline racemases by substrate-product analogues
M Harty, M Nagar, L Atkinson, CM LeGay, DJ Derksen, SL Bearne
Bioorganic & Medicinal Chemistry Letters 24 (1), 390-393, 2014
262014
Redefining the minimal substrate tolerance of mandelate racemase. Racemization of trifluorolactate
M Nagar, A Narmandakh, Y Khalak, SL Bearne
Biochemistry 50 (41), 8846-8852, 2011
232011
Photochemical control of protein arginine deiminase (PAD) activity
S Mondal, SS Parelkar, M Nagar, PR Thompson
ACS chemical biology 13 (4), 1057-1065, 2018
212018
Thioredoxin modulates protein arginine deiminase 4 (PAD4)-catalyzed citrullination
M Nagar, R Tilvawala, PR Thompson
Frontiers in immunology 10, 413103, 2019
192019
An Additional Role for the Brønsted Acid–Base Catalysts of Mandelate Racemase in Transition State Stabilization
M Nagar, SL Bearne
Biochemistry 54 (44), 6743-6752, 2015
152015
Inactivation of mandelate racemase by 3-hydroxypyruvate reveals a potential mechanistic link between enzyme superfamilies
M Nagar, BN Wyatt, M St. Maurice, SL Bearne
Biochemistry 54 (17), 2747-2757, 2015
132015
Altering the Y137-K164-K166 triad of mandelate racemase and its effect on the observed pKa of the Brønsted base catalysts
CM Fetter, ZA Morrison, M Nagar, CD Douglas, SL Bearne
Archives of biochemistry and biophysics 666, 116-126, 2019
102019
Altering the binding determinant on the interdigitating loop of mandelate racemase shifts specificity towards that of d-tartrate dehydratase
M Nagar, JA Hayden, E Sagey, G Worthen, M Park, AN Sharma, ...
Archives of Biochemistry and Biophysics 718, 109119, 2022
32022
A platform for chemical modification of mandelate racemase: characterization of the C92S/C264S and γ-thialysine 166 variants
M Nagar, H Kumar, SL Bearne
Protein Engineering, Design and Selection 31 (4), 135-145, 2018
22018
MANDELATE RACEMASE: INSIGHTS INTO SUBSTRATE TOLERANCE, NOVEL INHIBITOR-BINDING MODES, AND THE ROLE OF BINDING DETERMINANTS
M Nagar
2016
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