| Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues … Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, SW White, DD Miller, W Li, ... Journal of Medicinal Chemistry 62 (14), 6734-6750, 2019 | 66 | 2019 |
| Recent advances in heterocyclic tubulin inhibitors targeting the colchicine binding site X Wu, Q Wang, W Li Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2016 | 64 | 2016 |
| Lentiviral CRISPR/Cas9 nickase vector mediated BIRC5 editing inhibits epithelial to mesenchymal transition in ovarian cancer cells G Zhao, Q Wang, Q Gu, W Qiang, JJ Wei, P Dong, H Watari, W Li, J Yue Oncotarget 8 (55), 94666, 2017 | 52 | 2017 |
| Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment HW Humayun Sharif, L. Robert Hollingsworth, Andrew R. Griswold, Jeffrey C ... immunity 54, 1–13, 2021 | 51* | 2021 |
| A new oxyma derivative for nonracemizable amide-forming reactions in water Q Wang, Y Wang, M Kurosu Organic letters 14 (13), 3372-3375, 2012 | 46 | 2012 |
| Structural modification of the 3, 4, 5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, H Chen, Z Wu, J Yang, ... Journal of medicinal chemistry 61 (17), 7877-7891, 2018 | 43 | 2018 |
| Selective esterifications of primary alcohols in a water-containing solvent Y Wang, BA Aleiwi, Q Wang, M Kurosu Organic letters 14 (18), 4910-4913, 2012 | 41 | 2012 |
| Ovarian primary and metastatic tumors suppressed by survivin knockout or a novel survivin inhibitor G Zhao, Q Wang, Z Wu, X Tian, H Yan, B Wang, P Dong, H Watari, ... Molecular cancer therapeutics 18 (12), 2233-2245, 2019 | 31 | 2019 |
| Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer VK Kashyap, Q Wang, S Setua, PKB Nagesh, N Chauhan, S Kumari, ... Journal of Experimental & Clinical Cancer Research 38, 1-14, 2019 | 31 | 2019 |
| An orally available tubulin inhibitor, VERU-111, suppresses triple-negative breast cancer tumor growth and metastasis and bypasses taxane resistance S Deng, RI Krutilina, Q Wang, Z Lin, DN Parke, HC Playa, H Chen, ... Molecular cancer therapeutics 19 (2), 348-363, 2020 | 28 | 2020 |
| Oxidized thioredoxin-1 restrains the NLRP1 inflammasome DP Ball, LP Tsamouri, AE Wang, HC Huang, CD Warren, Q Wang, ... Science immunology 7 (77), eabm7200, 2022 | 22 | 2022 |
| Oxidized thioredoxin-1 restrains the NLRP1 inflammasome DAB Daniel P Ball, Alvin E. Wang, Charles D. Warren, Qinghui Wang, Andrew R ... BioRxiv, 2021 | 22* | 2021 |
| The NLRP1 and CARD8 inflammasomes detect reductive stress Q Wang, JC Hsiao, N Yardeny, HC Huang, CM O’Mara, EL Orth-He, ... Cell reports 42 (1), 2023 | 20 | 2023 |
| M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome DAB Sahana D. Rao#, Qifeng Chen#, Qinghui Wang#, Elizabeth L. Orth-He ... Nature Chemical biology, 2022 | 20 | 2022 |
| Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors Q Wang, KE Arnst, Y Xue, ZN Lei, D Ma, ZS Chen, DD Miller, W Li European journal of medicinal chemistry 149, 211-224, 2018 | 19 | 2018 |
| Flavonoids isolated from Sinopodophylli Fructus and their bioactivities against human breast cancer cells W Qing-Hui, GUO Shuai, Y Xue-Yan, YF Zhang, MY Shang, YH Shang, ... Chinese journal of natural medicines 15 (3), 225-233, 2017 | 17 | 2017 |
| Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation EL Orth-He, HC Huang, SD Rao, Q Wang, Q Chen, CM O’Mara, AJ Chui, ... Cell reports 42 (1), 2023 | 14 | 2023 |
| VERU-111 suppresses tumor growth and metastatic phenotypes of cervical cancer cells through the activation of p53 signaling pathway VK Kashyap, N Dan, N Chauhan, Q Wang, S Setua, PKB Nagesh, S Malik, ... Cancer letters 470, 64-74, 2020 | 13 | 2020 |
| Total synthesis of biologically active 20S-hydroxyvitamin D3 Q Wang, Z Lin, TK Kim, AT Slominski, DD Miller, W Li Steroids 104, 153-162, 2015 | 13 | 2015 |
| A ubiquitin-independent proteasome pathway controls activation of the CARD8 inflammasome JC Hsiao, AR Neugroschl, AJ Chui, CY Taabazuing, AR Griswold, ... Journal of Biological Chemistry 298 (7), 2022 | 8 | 2022 |
