| Crucial role of phospholipase Cε in chemical carcinogen-induced skin tumor development Y Bai, H Edamatsu, S Maeda, H Saito, N Suzuki, T Satoh, T Kataoka Cancer research 64 (24), 8808-8810, 2004 | 255 | 2004 |
| Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells J Kato-Stankiewicz, I Hakimi, G Zhi, J Zhang, I Serebriiskii, L Guo, ... Proceedings of the National Academy of Sciences 99 (22), 14398-14403, 2002 | 191 | 2002 |
| Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase Cε C Song, T Satoh, H Edamatsu, D Wu, M Tadano, X Gao, T Kataoka Oncogene 21 (53), 8105-8113, 2002 | 142 | 2002 |
| Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines H Edamatsu, CL Gau, T Nemoto, L Guo, F Tamanoi Oncogene 19 (27), 3059-3068, 2000 | 138 | 2000 |
| Phospholipase Cε promotes intestinal tumorigenesis of Apc Min/+ mice through augmentation of inflammation and angiogenesis M Li, H Edamatsu, R Kitazawa, S Kitazawa, T Kataoka Carcinogenesis 30 (8), 1424-1432, 2009 | 128 | 2009 |
| Protein farnesylation in mammalian cells: effects of farnesyltransferase inhibitors on cancer cells F Tamanoi, CL Gau, C Jiang, H Edamatsu, J Kato-Stankiewicz Cellular and Molecular Life Sciences CMLS 58, 1636-1649, 2001 | 113 | 2001 |
| Crucial role of phospholipase Cε in skin inflammation induced by tumor-promoting phorbol ester S Ikuta, H Edamatsu, M Li, L Hu, T Kataoka Cancer research 68 (1), 64-72, 2008 | 98 | 2008 |
| Congenital semilunar valvulogenesis defect in mice deficient in phospholipase Cε M Tadano, H Edamatsu, S Minamisawa, U Yokoyama, Y Ishikawa, ... Molecular and cellular biology, 2005 | 85 | 2005 |
| Activation of Stat1 and subsequent transcription of inducible nitric oxide synthase gene in C6 glioma cells is independent of interferon-γ-induced MAPK activation that is … YN T Nishiya, T Uehara, H Edamatsu, Y Kaziro, H Itoh FEBS Letters 408 (1), 33–38, 1997 | 83 | 1997 |
| LUCA15, a putative tumour suppressor gene encoding an RNA‐binding nuclear protein, is down‐regulated in ras‐transformed Rat‐1 cells H Edamatsu, Y Kaziro, H Itoh Genes to Cells 5 (10), 849-858, 2000 | 72 | 2000 |
| The M-Ras-RA-GEF-2-Rap1 Pathway Mediates Tumor Necrosis Factor-α–dependent Regulation of Integrin Activation in Splenocytes Y Yoshikawa, T Satoh, T Tamura, P Wei, SE Bilasy, H Edamatsu, A Aiba, ... Molecular biology of the cell 18 (8), 2949-2959, 2007 | 66 | 2007 |
| Potentiation of nitric oxide-induced apoptosis of MDA-MB-468 cells by farnesyltransferase inhibitor: implications in breast cancer S Pervin, R Singh, CL Gau, H Edamatsu, F Tamanoi, G Chaudhuri Cancer research 61 (12), 4701-4706, 2001 | 64 | 2001 |
| Crucial role of phospholipase Cε in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity L Hu, H Edamatsu, N Takenaka, S Ikuta, T Kataoka The journal of immunology 184 (2), 993-1002, 2010 | 55 | 2010 |
| Neuronal lineage‐specific induction of phospholipase Cε expression in the developing mouse brain D Wu, M Tadano, H Edamatsu, M Masago‐Toda, Y Yamawaki‐Kataoka, ... European Journal of Neuroscience 17 (8), 1571-1580, 2003 | 43 | 2003 |
| Enhancement of ultraviolet B-induced skin tumor development in phospholipase Cε -knockout mice is associated with decreased cell death M Oka, H Edamatsu, M Kunisada, L Hu, N Takenaka, S Dien, ... Carcinogenesis 31 (10), 1897-1902, 2010 | 41 | 2010 |
| p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5 T Kobayashi, J Ishida, M Musashi, S Ota, T Yoshida, Y Shimizu, M Chuma, ... International journal of cancer 128 (2), 304-318, 2011 | 38 | 2011 |
| Phospholipase Cɛ has a crucial role in ultraviolet B-induced neutrophil-associated skin inflammation by regulating the expression of CXCL1/KC M Oka, H Edamatsu, M Kunisada, L Hu, N Takenaka, M Sakaguchi, ... Laboratory investigation 91 (5), 711-718, 2011 | 33 | 2011 |
| Overexpression of phospholipase Cε in keratinocytes upregulates cytokine expression and causes dermatitis with acanthosis and T‐cell infiltration N Takenaka, H Edamatsu, N Suzuki, H Saito, Y Inoue, M Oka, L Hu, ... European journal of immunology 41 (1), 202-213, 2011 | 30 | 2011 |
| PLCε cooperates with the NF-κB pathway to augment TNFα-stimulated CCL2/MCP1 expression in human keratinocyte Y Harada, H Edamatsu, T Kataoka Biochemical and Biophysical Research Communications 414 (1), 106-111, 2011 | 28 | 2011 |
| Expression of an oncogenic mutant Gαi2 activates Ras in Rat-1 fibroblast cells H Edamatsu, Y Kaziro, H Itoh FEBS letters 440 (1-2), 231-234, 1998 | 28 | 1998 |
