| Novel Theranostic Opportunities Offered by Characterization of Altered Membrane Lipid Metabolism in Breast Cancer ProgressionLipidomic Changes in Breast Cancer Progression M Hilvo, C Denkert, L Lehtinen, B Müller, S Brockmöller, ... Cancer research 71 (9), 3236-3245, 2011 | 515 | 2011 |
| Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes M Oresic, S Simell, M Sysi-Aho, K Nanto-Salonen, T Seppanen-Laakso, ... The Journal of experimental medicine 205 (13), 2975-2984, 2008 | 484 | 2008 |
| A functional genomics approach toward the understanding of secondary metabolism in plant cells A Goossens, ST Häkkinen, I Laakso, T Seppänen-Laakso, S Biondi, ... Proceedings of the National Academy of Sciences 100 (14), 8595-8600, 2003 | 483 | 2003 |
| PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism G Medina-Gomez, SL Gray, L Yetukuri, K Shimomura, S Virtue, ... PLoS genetics 3 (4), e64, 2007 | 466 | 2007 |
| Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects–a monozygotic twin study KH Pietiläinen, M Sysi-Aho, A Rissanen, T Seppänen-Laakso, ... PloS one 2 (2), e218, 2007 | 445 | 2007 |
| Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells H Rischer, M Orešič, T Seppänen-Laakso, M Katajamaa, F Lammertyn, ... Proceedings of the National Academy of Sciences 103 (14), 5614-5619, 2006 | 390 | 2006 |
| Analysis of fatty acids by gas chromatography, and its relevance to research on health and nutrition T Seppänen-Laakso, I Laakso, R Hiltunen Analytica Chimica Acta 465 (1-2), 39-62, 2002 | 342 | 2002 |
| Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis L Yetukuri, M Katajamaa, G Medina-Gomez, T Seppänen-Laakso, ... BMC systems biology 1 (1), 1-15, 2007 | 287 | 2007 |
| Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ... PLoS biology 9 (6), e1000623, 2011 | 255 | 2011 |
| Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver A Kotronen, T Seppänen-Laakso, J Westerbacka, T Kiviluoto, J Arola, ... Diabetes 58 (1), 203-208, 2009 | 255 | 2009 |
| A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle R Laaksonen, M Katajamaa, H Päivä, M Sysi-Aho, L Saarinen, P Junni, ... PloS one 1 (1), e97, 2006 | 228 | 2006 |
| Ketogenic diet slows down mitochondrial myopathy progression in mice S Ahola-Erkkilä, CJ Carroll, K Peltola-Mjösund, V Tulkki, I Mattila, ... Human molecular genetics 19 (10), 1974-1984, 2010 | 209 | 2010 |
| Comparison of lipid and fatty acid composition of the liver, subcutaneous and intra‐abdominal adipose tissue, and serum A Kotronen, T Seppänen‐Laakso, J Westerbacka, T Kiviluoto, J Arola, ... Obesity 18 (5), 937-944, 2010 | 201 | 2010 |
| The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator–activated receptor-γ2 isoform G Medina-Gomez, S Virtue, C Lelliott, R Boiani, M Campbell, ... Diabetes 54 (6), 1706-1716, 2005 | 194 | 2005 |
| Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease VDF De Mello, M Lankinen, U Schwab, M Kolehmainen, S Lehto, ... Diabetologia 52, 2612-2615, 2009 | 177 | 2009 |
| The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus A Van Moerkercke, P Steensma, F Schweizer, J Pollier, I Gariboldi, ... Proceedings of the National Academy of Sciences 112 (26), 8130-8135, 2015 | 175 | 2015 |
| Human tear fluid lipidome: from composition to function AH Rantamäki, T Seppänen-Laakso, M Oresic, M Jauhiainen, ... PloS one 6 (5), e19553, 2011 | 166 | 2011 |
| Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy T Karpanen, M Bry, HM Ollila, T Seppänen-Laakso, E Liimatta, ... Circulation research 103 (9), 1018-1026, 2008 | 160 | 2008 |
| Metabolome in schizophrenia and other psychotic disorders: a general population-based study M Orešič, J Tang, T Seppänen-Laakso, I Mattila, SE Saarni, SI Saarni, ... Genome medicine 3, 1-14, 2011 | 157 | 2011 |
| Fatty fish intake decreases lipids related to inflammation and insulin signaling—a lipidomics approach M Lankinen, U Schwab, A Erkkilä, T Seppänen-Laakso, ML Hannila, ... PLoS one 4 (4), e5258, 2009 | 153 | 2009 |
