Tuulikki Seppanen-laakso
Tuulikki Seppanen-laakso
Senior Scientist
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Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression
M Hilvo, C Denkert, L Lehtinen, B Müller, S Brockmöller, ...
Cancer research 71 (9), 3236-3245, 2011
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
M Oresic, S Simell, M Sysi-Aho, K Nanto-Salonen, T Seppanen-Laakso, ...
The Journal of experimental medicine 205 (13), 2975-2984, 2008
A functional genomics approach toward the understanding of secondary metabolism in plant cells
A Goossens, ST Häkkinen, I Laakso, T Seppänen-Laakso, S Biondi, ...
Proceedings of the National Academy of Sciences 100 (14), 8595-8600, 2003
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
G Medina-Gomez, SL Gray, L Yetukuri, K Shimomura, S Virtue, ...
PLoS genetics 3 (4), e64, 2007
Acquired obesity is associated with changes in the serum lipidomic profile independent of genetic effects–a monozygotic twin study
KH Pietiläinen, M Sysi-Aho, A Rissanen, T Seppänen-Laakso, ...
PloS one 2 (2), e218, 2007
Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells
H Rischer, M Orešič, T Seppänen-Laakso, M Katajamaa, F Lammertyn, ...
Proceedings of the National Academy of Sciences 103 (14), 5614-5619, 2006
Analysis of fatty acids by gas chromatography, and its relevance to research on health and nutrition
T Seppänen-Laakso, I Laakso, R Hiltunen
Analytica Chimica Acta 465 (1-2), 39-62, 2002
Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis
L Yetukuri, M Katajamaa, G Medina-Gomez, T Seppänen-Laakso, ...
BMC systems biology 1, 1-15, 2007
Hepatic stearoyl-CoA desaturase (SCD)-1 activity and diacylglycerol but not ceramide concentrations are increased in the nonalcoholic human fatty liver
A Kotronen, T Seppänen-Laakso, J Westerbacka, T Kiviluoto, J Arola, ...
Diabetes 58 (1), 203-208, 2009
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans
KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ...
PLoS biology 9 (6), e1000623, 2011
A systems biology strategy reveals biological pathways and plasma biomarker candidates for potentially toxic statin-induced changes in muscle
R Laaksonen, M Katajamaa, H Päivä, M Sysi-Aho, L Saarinen, P Junni, ...
PloS one 1 (1), e97, 2006
Ketogenic diet slows down mitochondrial myopathy progression in mice
S Ahola-Erkkilä, CJ Carroll, K Peltola-Mjösund, V Tulkki, I Mattila, ...
Human molecular genetics 19 (10), 1974-1984, 2010
Comparison of lipid and fatty acid composition of the liver, subcutaneous and intra‐abdominal adipose tissue, and serum
A Kotronen, T Seppänen‐Laakso, J Westerbacka, T Kiviluoto, J Arola, ...
Obesity 18 (5), 937-944, 2010
The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus
A Van Moerkercke, P Steensma, F Schweizer, J Pollier, I Gariboldi, ...
Proceedings of the National Academy of Sciences 112 (26), 8130-8135, 2015
The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator–activated receptor-γ2 isoform
G Medina-Gomez, S Virtue, C Lelliott, R Boiani, M Campbell, ...
Diabetes 54 (6), 1706-1716, 2005
Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease
VDF De Mello, M Lankinen, U Schwab, M Kolehmainen, S Lehto, ...
Diabetologia 52, 2612-2615, 2009
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
T Karpanen, M Bry, HM Ollila, T Seppänen-Laakso, E Liimatta, ...
Circulation research 103 (9), 1018-1026, 2008
Human tear fluid lipidome: from composition to function
AH Rantamäki, T Seppänen-Laakso, M Oresic, M Jauhiainen, ...
PloS one 6 (5), e19553, 2011
Metabolome in schizophrenia and other psychotic disorders: a general population-based study
M Orešič, J Tang, T Seppänen-Laakso, I Mattila, SE Saarni, SI Saarni, ...
Genome medicine 3, 1-14, 2011
Fatty fish intake decreases lipids related to inflammation and insulin signaling—a lipidomics approach
M Lankinen, U Schwab, A Erkkilä, T Seppänen-Laakso, ML Hannila, ...
PLoS one 4 (4), e5258, 2009
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