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Fung T Lay
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Defensins-components of the innate immune system in plants
FT Lay, MA Anderson
Current protein and peptide science 6 (1), 85-101, 2005
5832005
Isolation and properties of floral defensins from ornamental tobacco and petunia
FT Lay, F Brugliera, MA Anderson
Plant physiology 131 (3), 1283-1293, 2003
2712003
The plant defensin, NaD1, enters the cytoplasm of Fusarium oxysporum hyphae
NL Van Der Weerden, FT Lay, MA Anderson
Journal of Biological Chemistry 283 (21), 14445-14452, 2008
2302008
Coexpression of potato type I and II proteinase inhibitors gives cotton plants protection against insect damage in the field
KM Dunse, JA Stevens, FT Lay, YM Gaspar, RL Heath, MA Anderson
Proceedings of the National Academy of Sciences 107 (34), 15011-15015, 2010
1922010
Phosphoinositide-mediated oligomerization of a defensin induces cell lysis
IKH Poon, AA Baxter, FT Lay, GD Mills, CG Adda, JAE Payne, TK Phan, ...
Elife 3, e01808, 2014
1912014
Convergent evolution of defensin sequence, structure and function
TMA Shafee, FT Lay, TK Phan, MA Anderson, MD Hulett
Cellular and Molecular Life Sciences 74, 663-682, 2017
1752017
The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP
FT Lay, HJ Schirra, MJ Scanlon, MA Anderson, DJ Craik
Journal of Molecular Biology 325 (1), 175-188, 2003
1742003
A pollen-specific RALF from tomato that regulates pollen tube elongation
PA Covey, CC Subbaiah, RL Parsons, G Pearce, FT Lay, MA Anderson, ...
Plant physiology 153 (2), 703-715, 2010
1482010
The defensins consist of two independent, convergent protein superfamilies
TMA Shafee, FT Lay, MD Hulett, MA Anderson
Molecular biology and evolution 33 (9), 2345-2356, 2016
1412016
Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds
BJC Janssen, HJ Schirra, FT Lay, MA Anderson, DJ Craik
Biochemistry 42 (27), 8214-8222, 2003
1302003
Novel insights on the mechanism of action of α‐amylase inhibitors from the plant defensin family
PB Pelegrini, FT Lay, AM Murad, MA Anderson, OL Franco
Proteins: Structure, Function, and Bioinformatics 73 (3), 719-729, 2008
1272008
Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects
AA Baxter, FT Lay, IKH Poon, M Kvansakul, MD Hulett
Cellular and molecular life sciences 74 (20), 3809-3825, 2017
1112017
The tomato defensin TPP3 binds phosphatidylinositol (4, 5)-bisphosphate via a conserved dimeric cationic grip conformation to mediate cell lysis
AA Baxter, V Richter, FT Lay, IKH Poon, CG Adda, PK Veneer, TK Phan, ...
Molecular and cellular biology 35 (11), 1964-1978, 2015
962015
Dimerization of plant defensin NaD1 enhances its antifungal activity
FT Lay, GD Mills, IKH Poon, NP Cowieson, N Kirby, AA Baxter, ...
Journal of Biological Chemistry 287 (24), 19961-19972, 2012
882012
X-ray structure of a carpet-like antimicrobial defensin–phospholipid membrane disruption complex
M Järvå, FT Lay, TK Phan, C Humble, IKH Poon, MR Bleackley, ...
Nature communications 9 (1), 1962, 2018
642018
The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions
FT Lay, S Poon, JA McKenna, AA Connelly, BL Barbeta, BS McGinness, ...
BMC plant biology 14, 1-13, 2014
582014
Human β-defensin 3 contains an oncolytic motif that binds PI (4, 5) P2 to mediate tumour cell permeabilisation
TK Phan, FT Lay, IKH Poon, MG Hinds, M Kvansakul, MD Hulett
Oncotarget 7 (2), 2054, 2016
542016
Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization
M Kvansakul, FT Lay, CG Adda, PK Veneer, AA Baxter, TK Phan, ...
Proceedings of the National Academy of Sciences 113 (40), 11202-11207, 2016
502016
Salt-tolerant antifungal and antibacterial activities of the corn defensin ZmD32
BK Kerenga, JA McKenna, PJ Harvey, P Quimbar, D Garcia-Ceron, ...
Frontiers in Microbiology 10, 795, 2019
482019
Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate–mediated membrane permeabilization
M Järvå, TK Phan, FT Lay, S Caria, M Kvansakul, MD Hulett
Science Advances 4 (7), eaat0979, 2018
472018
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