Siiri Iismaa
Siiri Iismaa
Senior Research Scientist, Victor Chang Cardiac Research Institute
Verified email at
Cited by
Cited by
Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders
SE Iismaa, BM Mearns, L Lorand, RM Graham
Physiological reviews 89 (3), 991-1023, 2009
Targeted inactivation of Gh/tissue transglutaminase II
N Nanda, SE Iismaa, WA Owens, A Husain, F Mackay, RM Graham
Journal of Biological Chemistry 276 (23), 20673-20678, 2001
A proliferative burst during preadolescence establishes the final cardiomyocyte number
N Naqvi, M Li, JW Calvert, T Tejada, JP Lambert, J Wu, SH Kesteven, ...
Cell 157 (4), 795-807, 2014
Identification of a chemotactic domain of the pro-inflammatory S100 protein CP-10.
M Lackmann, P Rajasekariah, SE Iismaa, G Jones, CJ Cornish, S Hu, ...
The Journal of Immunology 150 (7), 2981-2991, 1993
Oxidation regulates the inflammatory properties of the murine S100 protein S100A8
CA Harrison, MJ Raftery, J Walsh, P Alewood, SE Iismaa, S Thliveris, ...
Journal of Biological Chemistry 274 (13), 8561-8569, 1999
Mechanism of allosteric regulation of transglutaminase 2 by GTP
GE Begg, L Carrington, PH Stokes, JM Matthews, MA Wouters, A Husain, ...
Proceedings of the National Academy of Sciences 103 (52), 19683-19688, 2006
Transglutaminase 2 and its role in pulmonary fibrosis
KC Olsen, RE Sapinoro, RM Kottmann, AA Kulkarni, SE Iismaa, ...
American journal of respiratory and critical care medicine 184 (6), 699-707, 2011
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease
SJ McConoughey, M Basso, ZV Niatsetskaya, SF Sleiman, NA Smirnova, ...
EMBO molecular medicine 2 (9), 349-370, 2010
Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1
H Tatsukawa, Y Fukaya, G Frampton, A Martinez–Fuentes, K Suzuki, ...
Gastroenterology 136 (5), 1783-1795. e10, 2009
GTP binding and signaling by Gh/transglutaminase II involves distinct residues in a unique GTP-binding pocket
SE Iismaa, MJ Wu, N Nanda, WB Church, RM Graham
Journal of Biological Chemistry 275 (24), 18259-18265, 2000
Induction of the S100 chemotactic protein, CP-10, in murine microvascular endothelial cells by proinflammatory stimuli
T Yen, CA Harrison, JM Devery, S Leong, SE Iismaa, T Yoshimura, ...
Blood, The Journal of the American Society of Hematology 90 (12), 4812-4821, 1997
α1-Adrenergic receptor signaling via Gh is subtype specific and independent of its transglutaminase activity
S Chen, F Lin, S Iismaa, KN Lee, PJ Birckbichler, RM Graham
Journal of Biological Chemistry 271 (50), 32385-32391, 1996
Site-directed mutagenesis of Azotobacter vinelandii ferredoxin I. Changes in [4Fe-4S] cluster reduction potential and reactivity.
SE Iismaa, AE Vázquez, GM Jensen, PJ Stephens, JN Butt, FA Armstrong, ...
Journal of Biological Chemistry 266 (32), 21563-21571, 1991
The core domain of the tissue transglutaminase Gh hydrolyzes GTP and ATP
SE Iismaa, L Chung, MJ Wu, DC Teller, VC Yee, RM Graham
Biochemistry 36 (39), 11655-11664, 1997
Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity
SNP Murthy, S Iismaa, G Begg, DM Freymann, RM Graham, L Lorand
Proceedings of the National Academy of Sciences 99 (5), 2738-2742, 2002
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection
D Adlam, TM Olson, N Combaret, JC Kovacic, SE Iismaa, A Al-Hussaini, ...
Journal of the American College of Cardiology 73 (1), 58-66, 2019
Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity
GE Begg, SR Holman, PH Stokes, JM Matthews, RM Graham, SE Iismaa
Journal of Biological Chemistry 281 (18), 12603-12609, 2006
Construction and characterization of an Azotobacter vinelandii strain with mutations in the genes encoding flavodoxin and ferredoxin I
AE Martin, BK Burgess, SE Iismaa, CT Smartt, MR Jacobson, DR Dean
Journal of bacteriology 171 (6), 3162-3167, 1989
Comparative regenerative mechanisms across different mammalian tissues
SE Iismaa, X Kaidonis, AM Nicks, N Bogush, K Kikuchi, N Naqvi, ...
NPJ Regenerative medicine 3 (1), 1-20, 2018
Transglutaminase activity is present in highly purified nonsynaptosomal mouse brain and liver mitochondria
BF Krasnikov, SY Kim, SJ McConoughey, H Ryu, H Xu, I Stavrovskaya, ...
Biochemistry 44 (21), 7830-7843, 2005
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