| Stromal adipocyte enhancer-binding protein (AEBP1) promotes mammary epithelial cell hyperplasia via proinflammatory and hedgehog signaling RW Holloway, O Bogachev, AG Bharadwaj, GD McCluskey, ... Journal of Biological Chemistry 287 (46), 39171-39181, 2012 | 34 | 2012 |
| Exploring the potent inhibition of CTP synthase by gemcitabine‐5′‐triphosphate GD McCluskey, S Mohamady, SD Taylor, SL Bearne Chembiochem 17 (23), 2240-2249, 2016 | 33 | 2016 |
| A single historical substitution drives an increase in acetylcholine receptor complexity JR Emlaw, CJG Tessier, GD McCluskey, MS McNulty, Y Sheikh, ... Proceedings of the National Academy of Sciences 118 (7), e2018731118, 2021 | 13 | 2021 |
| “Pinching” the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage GD McCluskey, SL Bearne Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (12), 2714-2727, 2018 | 11 | 2018 |
| Biophysical analysis of bacterial CTP synthase filaments formed in the presence of the chemotherapeutic metabolite gemcitabine-5′-triphosphate GD McCluskey, SL Bearne Journal of molecular biology 430 (8), 1201-1217, 2018 | 8 | 2018 |
| Ancestral acetylcholine receptor β-subunit forms homopentamers that prime before opening spontaneously CJG Tessier, RM Sturgeon, JR Emlaw, GD McCluskey, FJ Pérez-Areales, ... Elife 11, e76504, 2022 | 4 | 2022 |
| A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate MJ McLeod, N Tran, GD McCluskey, TD Gillis, SL Bearne, T Holyoak Protein Science 32 (6), e4648, 2023 | 2 | 2023 |
| Substrate-product analogue inhibitors of isoleucine 2-epimerase from Lactobacillus buchneri by rational design NT Sorbara, JWM MacMillan, GD McCluskey, SL Bearne Organic & Biomolecular Chemistry 17 (37), 8618-8627, 2019 | 2 | 2019 |
| Anfractuous assemblies of IMP dehydrogenase and CTP synthase: new twists on regulation? GD McCluskey, SL Bearne The FEBS Journal 285 (20), 3724-3728, 2018 | 2 | 2018 |
| Gemcitabine is a Competitive Inhibitor of Cytidine‐5′‐triphosphate Synthase (CTPS) that Induces Enzyme Filament Polymerization G McCluskey, S Bearne The FASEB Journal 29, 722.7, 2015 | 2 | 2015 |
| Ancestral acetylcholine receptor beta-subunit forms homopentamers that prime before opening spontaneously C Tessier, RM Sturgeon, J Emlaw, G McCluskey, FJ Pérez-Areales, ... Biophysical Journal 122 (3), 247a, 2023 | | 2023 |
| A metal-dependent conformational change provides a structural basis for the inhibition of Escherichia coli CTP synthase by gemcitabine-5′-triphosphate MJ McLeod, N Tran, GD McCluskey, TD Gills, SL Bearne, T Holyoak Acta Crystallographica Section A: Foundations of Crystallography 79, a246-a246, 2022 | | 2022 |
| INVESTIGATION OF INHIBITION, FILAMENT FORMATION, AND INTER-DOMAIN AMMONIA CHANNELLING OF CTP SYNTHASE G McCluskey | | 2019 |
| Cover Picture: Exploring the Potent Inhibition of CTP Synthase by Gemcitabine‐5′‐Triphosphate (ChemBioChem 23/2016) GD McCluskey, S Mohamady, SD Taylor, SL Bearne ChemBioChem 17 (23), 2206-2206, 2016 | | 2016 |
