In vivo incorporation of unnatural amino acids P Schultz, L Wang, JC Anderson, JW Chin, DR Liu, TJ Magliery, ... US Patent 7,045,337, 2006 | 454 | 2006 |
Generation of a bacterium with a 21 amino acid genetic code RA Mehl, JC Anderson, SW Santoro, L Wang, AB Martin, DS King, ... Journal of the American Chemical Society 125 (4), 935-939, 2003 | 419 | 2003 |
Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs P Schultz, L Wang, JC Anderson, J Chin, DR Liu, TJ Magliery, ... US Patent 7,083,970, 2006 | 346 | 2006 |
Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific in Vivo Bioorthogonal Ligation with trans-Cyclooctenes JL Seitchik, JC Peeler, MT Taylor, ML Blackman, TW Rhoads, RB Cooley, ... Journal of the American Chemical Society 134 (6), 2898-2901, 2012 | 313 | 2012 |
Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET K Wang, A Sachdeva, DJ Cox, NM Wilf, K Lang, S Wallace, RA Mehl, ... Nature chemistry 6 (5), 393-403, 2014 | 306 | 2014 |
Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation A Darko, S Wallace, O Dmitrenko, MM Machovina, RA Mehl, JW Chin, ... Chemical science 5 (10), 3770-3776, 2014 | 284 | 2014 |
ATRP under biologically relevant conditions: grafting from a protein S Averick, A Simakova, S Park, D Konkolewicz, AJD Magenau, RA Mehl, ... ACS Macro Letters 1 (1), 6-10, 2012 | 274 | 2012 |
Protein 19F NMR in Escherichia coli C Li, GF Wang, Y Wang, R Creager-Allen, EA Lutz, H Scronce, KM Slade, ... Journal of the American Chemical Society 132 (1), 321-327, 2010 | 260 | 2010 |
Site-Specific Incorporation of a 19F-Amino Acid into Proteins as an NMR Probe for Characterizing Protein Structure and Reactivity JC Jackson, JT Hammill, RA Mehl Journal of the American Chemical Society 129 (5), 1160-1166, 2007 | 255 | 2007 |
Preparation of site-specifically labeled fluorinated proteins for 19F-NMR structural characterization JT Hammill, S Miyake-Stoner, JL Hazen, JC Jackson, RA Mehl Nature protocols 2 (10), 2601-2607, 2007 | 212 | 2007 |
Photo-cross-linking interacting proteins with a genetically encoded benzophenone IS Farrell, R Toroney, JL Hazen, RA Mehl, JW Chin Nature methods 2 (5), 377-384, 2005 | 209 | 2005 |
1, 2, 4-triazines are versatile bioorthogonal reagents DN Kamber, Y Liang, RJ Blizzard, F Liu, RA Mehl, KN Houk, JA Prescher Journal of the American Chemical Society 137 (26), 8388-8391, 2015 | 175 | 2015 |
The biosynthesis of nicotinamide adenine dinucleotides in bacteria TP Begley, C Kinsland, RA Mehl, A Osterman, P Dorrestein Vitamins & Hormones 61, 103-119, 2001 | 171 | 2001 |
Nitration of Hsp90 induces cell death MC Franco, Y Ye, CA Refakis, JL Feldman, AL Stokes, M Basso, ... Proceedings of the National Academy of Sciences 110 (12), E1102-E1111, 2013 | 168 | 2013 |
Probing protein folding using site-specifically encoded unnatural amino acids as FRET donors with tryptophan SJ Miyake-Stoner, AM Miller, JT Hammill, JC Peeler, KR Hess, RA Mehl, ... Biochemistry 48 (25), 5953-5962, 2009 | 162 | 2009 |
Genetically encoding protein oxidative damage H Neumann, JL Hazen, J Weinstein, RA Mehl, JW Chin Journal of the American Chemical Society 130 (12), 4028-4033, 2008 | 162 | 2008 |
Methods and composition for the production of orthogonal tRNA-aminoacyltRNA synthetase pairs PG Schultz, L Wang, JC Anderson, J Chin, DR Liu, TJ Magliery, ... US Patent 8,183,012, 2012 | 159 | 2012 |
Genetically encoded initiator for polymer growth from proteins JC Peeler, BF Woodman, S Averick, SJ Miyake-Stoner, AL Stokes, ... Journal of the American Chemical Society 132 (39), 13575-13577, 2010 | 149 | 2010 |
Ideal bioorthogonal reactions using a site-specifically encoded tetrazine amino acid RJ Blizzard, DR Backus, W Brown, CG Bazewicz, Y Li, RA Mehl Journal of the American Chemical Society 137 (32), 10044-10047, 2015 | 144 | 2015 |
Generating permissive site-specific unnatural aminoacyl-tRNA synthetases SJ Miyake-Stoner, CA Refakis, JT Hammill, H Lusic, JL Hazen, A Deiters, ... Biochemistry 49 (8), 1667-1677, 2010 | 130 | 2010 |