Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors E Wang, X Mi, MC Thompson, S Montoya, RQ Notti, J Afaghani, ... New England Journal of Medicine 386 (8), 735-743, 2022 | 125 | 2022 |
Urolithin A, a novel natural compound to target PI3K/AKT/mTOR pathway in pancreatic cancer TM Totiger, S Srinivasan, VR Jala, P Lamichhane, AR Dosch, ... Molecular cancer therapeutics 18 (2), 301-311, 2019 | 89 | 2019 |
Tobacco Carcinogen–Induced Production of Gm-Csf Activates Creb to Promote Pancreatic Cancer S Srinivasan, T Totiger, C Shi, J Castellanos, P Lamichhane, AR Dosch, ... Cancer research 78 (21), 6146-6158, 2018 | 40 | 2018 |
Prostate cancer targeted X-ray fluorescence imaging via gold nanoparticles functionalized with prostate-specific membrane antigen (PSMA) D Hara, W Tao, TM Totiger, A Pourmand, N Dogan, JC Ford, J Shi, ... International Journal of Radiation Oncology* Biology* Physics 111 (1), 220-232, 2021 | 22 | 2021 |
Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures B Diamond, B Ziccheddu, K Maclachlan, J Taylor, E Boyle, JA Ossa, ... Blood, The Journal of the American Society of Hematology 141 (19), 2359-2371, 2023 | 19 | 2023 |
Radiation attenuates prostate tumor antiviral responses to vesicular stomatitis virus containing IFNβ, resulting in pronounced antitumor systemic immune responses TS Udayakumar, DM Betancourt, A Ahmad, W Tao, TM Totiger, M Patel, ... Molecular cancer research 18 (8), 1232-1243, 2020 | 17 | 2020 |
Targeted therapy development in acute myeloid leukemia TM Totiger, A Ghoshal, J Zabroski, A Sondhi, S Bucha, J Jahn, Y Feng, ... Biomedicines 11 (2), 641, 2023 | 14 | 2023 |
Combination venetoclax and selinexor effective in relapsed refractory multiple myeloma with translocation t (11; 14) N Nguyen, S Chaudhry, TM Totiger, R Diaz, E Roberts, S Montoya, ... NPJ precision oncology 6 (1), 73, 2022 | 14 | 2022 |
Kinase dead BTK mutations confer resistance to covalent and noncovalent BTK inhibitors but are susceptible to clinical stage BTK degraders S Montoya, J Bourcier, MC Thompson, M Noviski, M Tan, E Wang, X Mi, ... Blood 140 (Supplement 1), 1811-1813, 2022 | 13 | 2022 |
Effect of lyophilized Azadirachta indica leaf powder on biochemical parameters of testis and epididymis in albino rats RH Aladakatti, MAG Ghodesawar, M Ahmed, TM Totiger, ... International Journal of Biological and Chemical Sciences 4 (1), 2010 | 11 | 2010 |
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127 S Montoya, J Bourcier, M Noviski, H Lu, MC Thompson, A Chirino, J Jahn, ... Science 383 (6682), eadi5798, 2024 | 10 | 2024 |
Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling S Mehra, S Srinivasan, S Singh, Z Zhou, V Garrido, IDC Silva, TM Totiger, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 323 (4 …, 2022 | 10 | 2022 |
Successful derivation of EGFP-transgenic embryonic stem cell line from a genetically non-permissive FVB/N mouse G Singh, TM Totiger, PB Seshagiri American Journal of Stem Cells 1 (2), 163, 2012 | 8 | 2012 |
Toward prediction of abscopal effect in radioimmunotherapy: pre-clinical investigation IB Mihaylov, TM Totiger, TM Giret, D Wang, B Spieler, S Welford PloS one 16 (8), e0255923, 2021 | 7 | 2021 |
Lung inflammation predictors in combined immune checkpoint-inhibitor and radiation therapy—proof-of-concept animal study B Spieler, TM Giret, S Welford, TM Totiger, IB Mihaylov Biomedicines 10 (5), 1173, 2022 | 4 | 2022 |
Protein biomarkers for response to XPO1 inhibition in haematologic malignancies TM Totiger, S Chaudhry, E Musi, J Afaghani, S Montoya, F Owusu‐Ansah, ... Journal of Cellular and Molecular Medicine 27 (4), 587-590, 2023 | 3 | 2023 |
A phase II clinical trial of E7820 for patients with Relapsed/Refractory myeloid malignancies with mutations in splicing factor genes JP Bewersdorf, MF Stahl, J Taylor, NS Chandhok, J Watts, A Derkach, ... Blood 140 (Supplement 1), 9065-9067, 2022 | 3 | 2022 |
Establishing correlations between breast tumor response to radio-immunotherapy and radiomics from multi-parametric imaging: an animal study A Ahmad, TM Totiger, AP Benaduce, B Marples, IB Mihaylov Applied sciences 10 (18), 6493, 2020 | 3 | 2020 |
XPO1 overexpression is a mechanism of resistance to eprenetapopt and 5-azacitidine therapy that can be therapeutically exploited for the treatment of TP53 mutated myeloid … TL Kruer, A Quintana, M Ferrall-Fairbanks, L Zhang, H Newman, ... Blood 140 (Supplement 1), 99-100, 2022 | 2 | 2022 |
Chemotherapy Signatures Map Evolution of Therapy-Related Myeloid Neoplasms B Diamond, B Ziccheddu, K Maclachlan, J Taylor, E Boyle, JA Ossa, ... BioRxiv, 2022.04. 26.489507, 2022 | 2 | 2022 |