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Nigel Peter Minton
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The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
M Sebaihia, BW Wren, P Mullany, NF Fairweather, N Minton, R Stabler, ...
Nature genetics 38 (7), 779-786, 2006
9462006
The role of toxin A and toxin B in Clostridium difficile infection
SA Kuehne, ST Cartman, JT Heap, ML Kelly, A Cockayne, NP Minton
Nature 467 (7316), 711-713, 2010
8432010
The ClosTron: a universal gene knock-out system for the genus Clostridium
JT Heap, OJ Pennington, ST Cartman, GP Carter, NP Minton
Journal of microbiological methods 70 (3), 452-464, 2007
7742007
The pMTL nic− cloning vectors. I. Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing
SP Chambers, SE Prior, DA Barstow, NP Minton
Gene 68 (1), 139-149, 1988
5511988
A modular system for Clostridium shuttle plasmids
JT Heap, OJ Pennington, ST Cartman, NP Minton
Journal of microbiological methods 78 (1), 79-85, 2009
4702009
The ClosTron: mutagenesis in Clostridium refined and streamlined
JT Heap, SA Kuehne, M Ehsaan, ST Cartman, CM Cooksley, JC Scott, ...
Journal of microbiological methods 80 (1), 49-55, 2010
4682010
Improved plasmid vectors for the isolation of translational lac gene fusions
NP Minton
Gene 31 (1-3), 269-273, 1984
3771984
Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier
D Purdy, TAT O'Keeffe, M Elmore, M Herbert, A McLeod, M Bokori‐Brown, ...
Molecular microbiology 46 (2), 439-452, 2002
3072002
Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis
SC Liu, NP Minton, AJ Giaccia, JM Brown
Gene therapy 9 (4), 291-296, 2002
2862002
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes
M Sebaihia, MW Peck, NP Minton, NR Thomson, MTG Holden, ...
Genome research 17 (7), 1082-1092, 2007
2852007
Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile
T Šapa, R Leuzzi, YK Ng, ST Baban, R Adamo, SA Kuehne, M Scarselli, ...
Journal of bacteriology 195 (3), 545-555, 2013
2682013
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954
JA Bridgewater, CJ Springer, RJ Knox, NP Minton, NP Michael, ...
European journal of cancer 31 (13-14), 2362-2370, 1995
2571995
Precise Manipulation of the Clostridium difficile Chromosome Reveals a Lack of Association between the tcdC Genotype and Toxin Production
ST Cartman, ML Kelly, D Heeg, JT Heap, NP Minton
Applied and environmental microbiology 78 (13), 4683-4690, 2012
2532012
Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment
MJ Lemmon, P Van Zijl, ME Fox, ML Mauchline, AJ Giaccia, NP Minton, ...
Gene therapy 4 (8), 791-796, 1997
2501997
Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia.
ME Fox, MJ Lemmon, ML Mauchline, TO Davis, AJ Giaccia, NP Minton, ...
Gene therapy 3 (2), 173-178, 1996
2331996
Femtomolar sensitivity of a NO sensor from Clostridium botulinum
P Nioche, V Berka, J Vipond, N Minton, AL Tsai, CS Raman
Science 306 (5701), 1550-1553, 2004
2282004
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker
JT Heap, M Ehsaan, CM Cooksley, YK Ng, ST Cartman, K Winzer, ...
Nucleic acids research 40 (8), e59-e59, 2012
2242012
Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain
SA Kuehne, MM Collery, ML Kelly, ST Cartman, A Cockayne, NP Minton
The Journal of infectious diseases 209 (1), 83-86, 2014
2142014
Clostridia in cancer therapy
NP Minton
Nature Reviews Microbiology 1 (3), 237-242, 2003
2142003
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene
DE THOMPSON, JK BREHM, JD OULTRAM, TJ SWINFIELD, CC SHONE, ...
European journal of biochemistry 189 (1), 73-81, 1990
2111990
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