|Docking studies on isoform-specific inhibition of phosphoinositide-3-kinases|
DA Sabbah, JL Vennerstrom, H Zhong
Journal of chemical information and modeling 50 (10), 1887-1898, 2010
|Dual inhibitors of PI3K/mTOR or mTOR-selective inhibitors: which way shall we go?|
D A Sabbah, M G Brattain, H Zhong
Current medicinal chemistry 18 (36), 5528-5544, 2011
|N-Phenyl-4-hydroxy-2-quinolone-3-carboxamides as selective inhibitors of mutant H1047R phosphoinositide-3-kinase (PI3Kα)|
DA Sabbah, NA Simms, W Wang, Y Dong, EL Ezell, MG Brattain, ...
Bioorganic & medicinal chemistry 20 (24), 7175-7183, 2012
|Binding selectivity studies of phosphoinositide 3-kinases using free energy calculations|
DA Sabbah, JL Vennerstrom, HA Zhong
Journal of chemical information and modeling 52 (12), 3213-3224, 2012
|Biological evaluation and docking studies of recently identified inhibitors of phosphoinositide-3-kinases|
DA Sabbah, NA Simms, MG Brattain, JL Vennerstrom, H Zhong
Bioorganic & medicinal chemistry letters 22 (2), 876-880, 2012
|Advances in the development of class I phosphoinositide 3-Kinase (PI3K) inhibitors|
DA Sabbah, J Hu, HA Zhong
Curr Top Med Chem 16 (13), 1413-26, 2016
|Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors|
K Sweidan, DA Sabbah, S Bardaweel, KA Dush, GA Sheikha, ...
Bioorganic & medicinal chemistry letters 26 (11), 2685-2690, 2016
|Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)|
DA Sabbah, M Saada, RA Khalaf, S Bardaweel, K Sweidan, T Al-Qirim, ...
Bioorganic & medicinal chemistry letters 25 (16), 3120-3124, 2015
|Modeling the protonation states of β-secretase binding pocket by molecular dynamics simulations and docking studies|
DA Sabbah, HA Zhong
Journal of Molecular Graphics and Modelling 68, 206-215, 2016
|Synthesis and preliminary biological evaluation of new heterocyclic carboxamide models|
K Sweidan, J Engelmann, W Abu Rayyan, D Sabbah, M Abu Zarga, ...
Letters in Drug Design & Discovery 12 (5), 417-429, 2015
|Computational docking studies of novel heterocyclic carboxamides as potential PI3Kα inhibitors|
K Sweidan, D A Sabbah, J Engelmann, H Abdel-Halim, G Abu Sheikha
Letters in Drug Design & Discovery 12 (10), 856-863, 2015
|Structure-Based Design: Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential Cytotoxic Agents|
DA Sabbah, B Hishmah, K Sweidan, S Bardaweel, M AlDamen, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018
|Antilipase and antiproliferative activities of novel fluoroquinolones and triazolofluoroquinolones|
S Arabiyat, V Kasabri, Y Al‐Hiari, YK Bustanji, R Albashiti, IM Almasri, ...
Chemical biology & drug design 90 (6), 1282-1294, 2017
|Facile synthesis, characterization, and cytotoxicity study of new 3-(indol-2-yl) bicyclotetrazatridecahexaens|
K Sweidan, DA Sabbah, S Bardaweel, G Abu Sheikha, T Al-Qirim, H Salih, ...
Canadian Journal of Chemistry 95 (8), 858-862, 2017
|Benzoin schiff bases: Design, synthesis, and biological evaluation as potential antitumor agents|
DA Sabbah, F Al-Tarawneh, WH Talib, K Sweidan, SK Bardaweel, ...
Medicinal Chemistry 14 (7), 695-708, 2018
|Cholesterol-coated gold nanorods as an efficient nano-carrier for chemotherapeutic delivery and potential treatment of breast cancer: in vitro studies using the MCF-7 cell line|
NN Mahmoud, DA Sabbah, R Abu-Dahab, D Abuarqoub, M Abdallah, ...
RSC advances 9 (22), 12718-12731, 2019
|Molecular Docking Studies of Novel Thiosemicarbazone-Based Indoles as Potential PI3Kα Inhibitors|
DA Sabbah, K Sweidan
Letters in Drug Design & Discovery, 2017
|Molecular docking and pharmacophore modeling studies of fluorinated benzamides as potential CETP inhibitors|
R Abu Khalaf, S Al-Rawashdeh, D Sabbah, G Abu Sheikha
Medicinal Chemistry 13 (3), 239-253, 2017
|CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping and Synthesis|
R Abu Khalaf, H Abd El-Aziz, D Sabbah, G Albadawi, G Abu Sheikha
Letters in Drug Design & Discovery 14 (12), 1391-1400, 2017
|Synthesis and in vivo anti-hyperlipidemic activity of novel n-benzoylphenyl-2-furamide derivatives in Wistar rats|
S Hikmat, T Al-qirim, D Alkabbani, G Shattat, GA Sheikha, D Sabbah, ...
Tropical Journal of Pharmaceutical Research 16 (1), 193-201, 2017