Brian J. Cafferty
Brian J. Cafferty
Senior Scientist, Beam Therapeutics
Verified email at - Homepage
Cited by
Cited by
The origin of RNA and “my grandfather’s axe”
NV Hud, BJ Cafferty, R Krishnamurthy, LD Williams
Chemistry & biology 20 (4), 466-474, 2013
The synthesis of cyclic poly (ethylene imine) and exact linear analogues: an evaluation of gene delivery comparing polymer architectures
MA Cortez, WT Godbey, Y Fang, ME Payne, BJ Cafferty, KA Kosakowska, ...
Journal of the american chemical society 137 (20), 6541-6549, 2015
Efficient self-assembly in water of long noncovalent polymers by nucleobase analogues
BJ Cafferty, I Gállego, MC Chen, KI Farley, R Eritja, NV Hud
Journal of the American Chemical Society 135 (7), 2447-2450, 2013
Spontaneous formation and base pairing of plausible prebiotic nucleotides in water
BJ Cafferty, DM Fialho, J Khanam, R Krishnamurthy, NV Hud
Nature communications 7 (1), 1-8, 2016
Darwin's warm little pond: a one‐pot reaction for prebiotic phosphorylation and the mobilization of phosphate from minerals in a urea‐based solvent
B Burcar, M Pasek, M Gull, BJ Cafferty, F Velasco, NV Hud, ...
Angewandte Chemie International Edition 55 (42), 13249-13253, 2016
Spontaneous Prebiotic Formation of a β-Ribofuranoside That Self-Assembles with a Complementary Heterocycle
MC Chen, BJ Cafferty, I Mamajanov, I Gállego, J Khanam, ...
Journal of the American Chemical Society 136 (15), 5640–5646, 2014
Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology
BJ Cafferty, NV Hud
Current opinion in chemical biology 22, 146-157, 2014
Was a Pyrimidine‐Pyrimidine Base Pair the Ancestor of Watson‐Crick Base Pairs? Insights from a Systematic Approach to the Origin of RNA
BJ Cafferty, NV Hud
Israel Journal of Chemistry 55 (8), 891-905, 2015
Storage of information using small organic molecules
BJ Cafferty, AS Ten, MJ Fink, S Morey, DJ Preston, M Mrksich, ...
ACS central science 5 (5), 911-916, 2019
Ultra-sensitive pH control of supramolecular polymers and hydrogels: p K a matching of biomimetic monomers
BJ Cafferty, RR Avirah, GB Schuster, NV Hud
Chemical Science 5 (12), 4681-4686, 2014
Spontaneous symmetry breaking in the formation of supramolecular polymers: implications for the origin of biological homochirality
SC Karunakaran, BJ Cafferty, A Weigert‐Muńoz, GB Schuster, NV Hud
Angewandte Chemie International Edition 58 (5), 1453-1457, 2019
Autocatalytic Cycles in a Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction
SN Semenov, L Belding, BJ Cafferty, MPS Mousavi, AM Finogenova, ...
Journal of the American Chemical Society 140 (32), 10221-10232, 2018
Formation of supramolecular assemblies and liquid crystals by purine nucleobases and cyanuric acid in water: Implications for the possible origins of RNA
C Li, BJ Cafferty, SC Karunakaran, GB Schuster, NV Hud
Physical Chemistry Chemical Physics 18 (30), 20091-20096, 2016
Fabricating 3D structures by combining 2D printing and relaxation of strain
BJ Cafferty, VE Campbell, P Rothemund, DJ Preston, A Ainla, ...
Advanced Materials Technologies 4 (1), 1800299, 2019
Robustness, entrainment, and hybridization in dissipative molecular networks, and the origin of life
BJ Cafferty, ASY Wong, SN Semenov, L Belding, S Gmür, WTS Huck, ...
Journal of the American Chemical Society 141 (20), 8289-8295, 2019
Nonenzymatic ligation of DNA with a reversible step and a final linkage that can be used in PCR
AE Engelhart, BJ Cafferty, CD Okafor, MC Chen, LD Williams, DG Lynn, ...
ChemBioChem 13 (8), 1121-1124, 2012
Using a chitosan nanolayer as an efficient pH buffer to protect pH-sensitive supramolecular assemblies
DV Andreeva, A Kollath, N Brezhneva, DV Sviridov, BJ Cafferty, ...
Physical Chemistry Chemical Physics 19 (35), 23843-23848, 2017
Silicate-promoted phosphorylation of glycerol in non-aqueous solvents: a prebiotically plausible route to organophosphates
M Gull, BJ Cafferty, NV Hud, MA Pasek
Life 7 (3), 29, 2017
Exquisite regulation of supramolecular equilibrium polymers in water: chain stoppers control length, polydispersity and viscoelasticity
SC Karunakaran, BJ Cafferty, M Peláez-Fernández, K Neselu, ...
Polymer Chemistry 9 (43), 5268-5277, 2018
Reversible Transformation of a Supramolecular Hydrogel by Redox Switching of Methylene Blue—A Noncovalent Chain Stopper
SC Karunakaran, BJ Cafferty, KS Jain, GB Schuster, NV Hud
ACS omega 5 (1), 344-349, 2019
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