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Dr. Thelma Abeysinghe
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A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase
Z Wang, T Abeysinghe, JS Finer-Moore, RM Stroud, A Kohen
Journal of the American Chemical Society 134 (42), 17722-17730, 2012
622012
Phytochemical screening, total polyphenol, flavonoid content, in vitro antioxidant and antibacterial activities of Sri Lankan varieties of Murraya koenigii and Micromelum …
DT Abeysinghe, KAH Kumara, KAD Kaushalya, UG Chandrika, D Alwis
Heliyon 7 (7), 2021
562021
Era of genomic medicine: a narrative review on CRISPR technology as a potential therapeutic tool for human diseases
OW Kotagama, CD Jayasinghe, T Abeysinghe
BioMed research international 2019, 2019
452019
Linking protein motion to enzyme catalysis
P Singh, T Abeysinghe, A Kohen
Molecules 20 (1), 1192-1209, 2015
422015
Mg2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active Site
Z Wang, PJ Sapienza, T Abeysinghe, C Luzum, AL Lee, JS Finer-Moore, ...
Journal of the American Chemical Society 135 (20), 7583-7592, 2013
312013
Nutritive importance and therapeutics uses of three different varieties (Murraya koenigii, Micromelum minutum, and Clausena indica) of curry leaves: An updated review
DT Abeysinghe, D Alwis, KAH Kumara, UG Chandrika
Evidence-Based Complementary and Alternative Medicine 2021, 2021
222021
Antimicrobial activity and phytochemical screening of Alpinia malaccensis (Ran‐kiriya) against food‐borne bacteria
T Somarathna, W Fernando, K Ranaweera, GAS Premakumara, ...
Journal of applied microbiology 125 (5), 1276-1285, 2018
172018
DNAzymes, novel therapeutic agents in cancer therapy: a review of concepts to applications
IBK Thomas, KAP Gaminda, CD Jayasinghe, DT Abeysinghe, ...
Journal of Nucleic Acids 2021, 2021
122021
The general base in the thymidylate synthase catalyzed proton abstraction
AK Ghosh, Z Islam, J Krueger, T Abeysinghe, A Kohen
Physical Chemistry Chemical Physics 17 (46), 30867-30875, 2015
92015
Role of long-range protein dynamics in different thymidylate synthase catalyzed reactions
T Abeysinghe, A Kohen
International Journal of Molecular Sciences 16 (4), 7304-7319, 2015
82015
Preserved hydride transfer mechanism in evolutionarily divergent thymidylate synthases
T Abeysinghe, B Hong, Z Wang, A Kohen
Current topics in biochemical research 17, 19, 2016
42016
Green synthesis of iron nanoparticles using Syzygium aromaticum extracts and their applications: Nitrate removal, malachite green degradation and antibacterial activity
KAP Gaminda, IBK Thomas, P Lakmauri, T Abeysinghe, C Jayasinghe, ...
Environmental Nanotechnology, Monitoring & Management 21, 100925, 2024
2024
Computational investigation of impact of Pb (II) and Ni (II) ions on hUNG enzyme: insights from molecular dynamics simulations
PR Paligaspe, S Weerasinghe, DP Dissanayake, R Senthilnithy, ...
Journal of Biomolecular Structure and Dynamics, 1-10, 2024
2024
Comparative assessment of the efficiency and accuracy of the kirkwood-buff force field in protein molecular dynamics simulations: an in-silico investigation
PR Paligaspe, S Weerasinghe, DP Dissanayake, R Senthilnithy, ...
Faculty of Applied Sciences, South Eastern University of Sri Lanka …, 2023
2023
SARS-CoV-2 Detection by Functional Nucleic Acids–A Review
KAP Gaminda, T Abeysinghe, C Jayasinghe, R Senthilnithy
Sri Lankan Journal of Applied Sciences 2 (01), 24-38, 2023
2023
Deoxyribozymes in detection of pathogenic bacteria
KAP Gaminda, IBK Thomas, DT Abeysinghe, CD Jayasinghe, ...
Biotechnologia Acta 14 (5), 5-20, 2021
2021
In vitro assessment of antioxidant, antimicrobial and phytochemical screening of crude methanolic extract of leaves of Murraya koenigii growing in Sri Lanka
T Abeysinghe, KAH Kumara, D Alwis, UG Chandrika
Faculty of Science, University of Ruhuna, Matara, Sri Lanka, 2020
2020
Comparative study on Proximate and Mineral composition in Vernonia cinerea
P Weerasinghe, T Abeysinghe, PA Paranagama
International Postgraduate Research Conference 2019, Faculty of Graduate …, 2019
2019
Determination of narcotic (morphine, codeine, 6-monoacetylmorphine) levels in human urine by gas chromatoghraphy
IDM Manohari, WDV Karunaratne, T Abeysinghe
4th International Research Symposium on Pure and Applied Sciences, Faculty …, 2019
2019
Assessment of in vitro antioxidant activity and flavonoid content Vernonia cinerea
P Weerasinghe, T Abeysinghe, PA Paranagama
4th International Research Symposium on Pure and Applied Sciences, Faculty …, 2019
2019
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