Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist SI Sayin, A Wahlström, J Felin, S Jäntti, HU Marschall, K Bamberg, ... Cell metabolism 17 (2), 225-235, 2013 | 1213 | 2013 |
Human gut microbes impact host serum metabolome and insulin sensitivity HK Pedersen, V Gudmundsdottir, HB Nielsen, T Hyotylainen, T Nielsen, ... Nature 535 (7612), 376-381, 2016 | 834 | 2016 |
The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes AD Kostic, D Gevers, H Siljander, T Vatanen, T Hyötyläinen, ... Cell host & microbe 17 (2), 260-273, 2015 | 701 | 2015 |
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression M Hilvo, C Denkert, L Lehtinen, B Müller, S Brockmöller, ... Cancer research 71 (9), 3236-3245, 2011 | 389 | 2011 |
Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease PK Luukkonen, Y Zhou, S Sädevirta, M Leivonen, J Arola, M Orešič, ... Journal of hepatology 64 (5), 1167-1175, 2016 | 234 | 2016 |
Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathy A Götz, H Tyynismaa, L Euro, P Ellonen, T Hyötyläinen, T Ojala, ... The American Journal of Human Genetics 88 (5), 635-642, 2011 | 228 | 2011 |
Metabolome in progression to Alzheimer's disease M Orešič, T Hyötyläinen, SK Herukka, M Sysi-Aho, I Mattila, ... Translational psychiatry 1 (12), e57-e57, 2011 | 213 | 2011 |
Comprehensive two-dimensional liquid chromatography in analysis of Lamiaceae herbs: characterisation and quantification of antioxidant phenolic acids M Kivilompolo, T Hyötyläinen Journal of Chromatography A 1145 (1-2), 155-164, 2007 | 202 | 2007 |
The role of VOC oxidation products in continental new particle formation A Laaksonen, M Kulmala, CD O'Dowd, J Joutsensaari, P Vaattovaara, ... Atmospheric Chemistry and Physics 8 (10), 2657-2665, 2008 | 196 | 2008 |
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ... PLoS Biol 9 (6), e1000623, 2011 | 187 | 2011 |
Characterisation of Stevia rebaudiana by comprehensive two-dimensional liquid chromatography time-of-flight mass spectrometry J Pól, B Hohnová, T Hyötyläinen Journal of Chromatography A 1150 (1-2), 85-92, 2007 | 182 | 2007 |
Determination of brominated flame retardants in environmental samples T Hyötyläinen, K Hartonen TrAC Trends in Analytical Chemistry 21 (1), 13-30, 2002 | 168 | 2002 |
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress K Ketola, M Hilvo, T Hyötyläinen, A Vuoristo, AL Ruskeepää, M Orešič, ... British journal of cancer 106 (1), 99-106, 2012 | 161 | 2012 |
Sorbent-and liquid-phase microextraction techniques and membrane-assisted extraction in combination with gas chromatographic analysis: A review T Hyötyläinen, ML Riekkola Analytica chimica acta 614 (1), 27-37, 2008 | 159 | 2008 |
Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma JA Bowden, A Heckert, CZ Ulmer, CM Jones, JP Koelmel, L Abdullah, ... Journal of lipid research 58 (12), 2275-2288, 2017 | 157 | 2017 |
Size and composition measurements of background aerosol and new particle growth in a Finnish forest during QUEST 2 using an Aerodyne Aerosol Mass Spectrometer JD Allan, MR Alfarra, KN Bower, H Coe, JT Jayne, DR Worsnop, PP Aalto, ... Atmospheric Chemistry and Physics 6 (2), 315-327, 2006 | 156 | 2006 |
Critical evaluation of sample pretreatment techniques T Hyötyläinen Analytical and bioanalytical chemistry 394 (3), 743-758, 2009 | 145 | 2009 |
Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars PK Luukkonen, S Sädevirta, Y Zhou, B Kayser, A Ali, L Ahonen, ... Diabetes care 41 (8), 1732-1739, 2018 | 132 | 2018 |
Characterising metabolically healthy obesity in weight-discordant monozygotic twins J Naukkarinen, S Heinonen, A Hakkarainen, J Lundbom, K Vuolteenaho, ... Diabetologia 57 (1), 167-176, 2014 | 132 | 2014 |
Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics for studies of body fluids and tissues H Nygren, T Seppänen-Laakso, S Castillo, T Hyötyläinen, M Orešič Metabolic Profiling, 247-257, 2011 | 130 | 2011 |