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bappaditya chandra
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Methods for physical characterization of phase-separated bodies and membrane-less organelles
DM Mitrea, B Chandra, MC Ferrolino, EB Gibbs, M Tolbert, MR White, ...
Journal of molecular biology 430 (23), 4773-4805, 2018
1402018
Significant Structural Differences between Transient Amyloid‐β Oligomers and Less‐Toxic Fibrils in Regions Known To Harbor Familial Alzheimer′ s Mutations
B Sarkar, VS Mithu, B Chandra, A Mandal, M Chandrakesan, D Bhowmik, ...
Angewandte Chemie 126 (27), 7008-7012, 2014
1072014
Cell-membrane-mimicking lipid-coated nanoparticles confer Raman enhancement to membrane proteins and reveal membrane-attached amyloid-β conformation
D Bhowmik, KR Mote, CM MacLaughlin, N Biswas, B Chandra, JK Basu, ...
ACS nano 9 (9), 9070-9077, 2015
992015
Phase separation mediates NUP98 fusion Oncoprotein leukemic transformation
B Chandra, NL Michmerhuizen, HK Shirnekhi, S Tripathi, BJ Pioso, ...
Cancer Discovery 12 (4), 1152-1169, 2022
732022
Major Reaction Coordinates Linking Transient Amyloid-β Oligomers to Fibrils Measured at Atomic Level
B Chandra, D Bhowmik, BK Maity, KR Mote, D Dhara, R Venkatramani, ...
Biophysical Journal 113 (4), 805-816, 2017
412017
Ordered and Disordered Segments of Amyloid-β Drive Sequential Steps of the Toxic Pathway
BK Maity, AK Das, S Dey, UK Moorthi, A Kaur, A Dey, D Surendran, ...
ACS chemical neuroscience 10 (5), 2498-2509, 2019
252019
Aggregation-induced conformation changes dictate islet amyloid polypeptide (IAPP) membrane affinity
A Rawat, BK Maity, B Chandra, S Maiti
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1734-1740, 2018
242018
Curcumin Dictates Divergent Fates for the Central Salt Bridges in Amyloid-β40 and Amyloid-β42
B Chandra, VS Mithu, D Bhowmik, AK Das, B Sahoo, S Maiti, PK Madhu
Biophysical Journal 112 (8), 1597-1608, 2017
192017
Emerging structural details of transient amyloid-β oligomers suggest designs for effective small molecule modulators
B Chandra, S Halder, J Adler, A Korn, D Huster, S Maiti
Chemical Physics Letters 675, 51-55, 2017
182017
Perturbation of the F19-L34 Contact in Amyloid β (1-40) Fibrils Induces Only Local Structural Changes but Abolishes Cytotoxicity
F Hoffmann, J Adler, B Chandra, KR Mote, G Bekcioglu-Neff, D Sebastiani, ...
The journal of physical chemistry letters 8 (19), 4740-4745, 2017
162017
Enhanced two photon absorption cross section and optical nonlinearity of a quasi-octupolar molecule
CKR Namboodiri, SR Bongu, PB Bisht, R Mukkamala, B Chandra, ...
Journal of Photochemistry and Photobiology A: Chemistry 314, 60-65, 2016
132016
Defining the condensate landscape of fusion oncoproteins
S Tripathi, HK Shirnekhi, SD Gorman, B Chandra, DW Baggett, CG Park, ...
Nature Communications 14 (1), 6008, 2023
112023
Fluorescence quenching by lipid encased nanoparticles shows that amyloid-β has a preferred orientation in the membrane
B Chandra, BK Maity, A Das, S Maiti
Chemical Communications 54 (56), 7750-7753, 2018
112018
Stereoisomers Probe Steric Zippers in Amyloid-β
B Chandra, A Korn, BK Maity, J Adler, A Rawat, M Krueger, D Huster, ...
The Journal of Physical Chemistry B 121 (8), 1835-1842, 2017
112017
Solvatochromism, multiphoton fluorescence, and resonance energy transfer in a new octupolar dye-pair
C.K.R. Namboodiria, P.B. Bishta, R. Mukkamalab, B
Chemical Physics 415, 190, 2013
112013
The Role of Phase-Separated Condensates in Fusion Oncoprotein–Driven Cancers
HK Shirnekhi, B Chandra, RW Kriwacki
Annual Review of Cancer Biology 7, 73-91, 2023
102023
Design of heat shock-resistant surfaces to prevent protein aggregation: Enhanced chaperone activity of immobilized α-Crystallin
N Ray, S Roy, S Singha, B Chandra, AK Dasgupta, A Sarkar
Bioconjugate chemistry 25 (5), 888-895, 2014
42014
Secondary Structure Flipping Connected to Salt-Bridge Formation Converts Toxic Amyloid-β40 Oligomers to Fibrils
B Chandra, D Bhowmik, BK Maity, KR Mote, D Dhara, K Bera, A Das, ...
Biophysical Journal 112 (3), 362a-363a, 2017
32017
AML-158 Phase Separation Mediates NUP98 Fusion Oncoprotein Leukemic Transformation
N Michmerhuizen, B Chandra, H Shirnekhi, S Tripathi, B Pioso, D Baggett, ...
Clinical Lymphoma Myeloma and Leukemia 22, S220, 2022
12022
Charting the human disease condensate dysregulome
B Chandra, R Kriwacki
Developmental Cell 57 (14), 1677-1679, 2022
12022
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