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Ashley E. Modell
Ashley E. Modell
Broad Institute
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
Systematic targeting of protein–protein interactions
AE Modell, SL Blosser, PS Arora
Trends in pharmacological sciences 37 (8), 702-713, 2016
1722016
Targeting unoccupied surfaces on protein–protein interfaces
D Rooklin, AE Modell, H Li, V Berdan, PS Arora, Y Zhang
Journal of the American Chemical Society 139 (44), 15560-15563, 2017
522017
CRISPR-based therapeutics: current challenges and future applications
AE Modell, D Lim, TM Nguyen, V Sreekanth, A Choudhary
Trends in pharmacological sciences, 2021
412021
Bifunctional modalities for repurposing protein function
AE Modell, S Lai, TM Nguyen, A Choudhary
Cell Chemical Biology 28 (7), 1081-1089, 2021
212021
Emerging Diabetes Therapies: Bringing back the β-cells
G Basile, MMF Qadir, F Mauvais-Jarvis, A Vetere, V Shoba, AE Modell, ...
Molecular Metabolism, 101477, 2022
202022
Peptide Tethering: Pocket-Directed Fragment Screening for Peptidomimetic Inhibitor Discovery
AE Modell, F Marrone III, NR Panigrahi, Y Zhang, PS Arora
Journal of the American Chemical Society 144 (3), 1198-1204, 2022
142022
Chemical and optical control of CRISPR-associated nucleases
AE Modell, SU Siriwardena, VM Shoba, X Li, A Choudhary
Current Opinion in Chemical Biology 60, 113-121, 2021
112021
Rational Design of Silicon‐Based Zinc Ionophores
K Yamada, A Deb, VM Shoba, D Lim, B Maji, AE Modell, A Choudhary
Angewandte Chemie 134 (23), e202201698, 2022
32022
A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems
AE Modell, SU Siriwardena, A Choudhary
Biochemistry 59 (20), 1869-1870, 2020
22020
Proximity‐Inducing Bifunctional Molecules Beyond PROTACs
S Lai, AE Modell, A Choudhary
Protein Homeostasis in Drug Discovery: A Chemical Biology Perspective, 419-446, 2022
12022
Chemical Approaches for Beta-cell Biology
A Vetere, VS Parekh, AE Modell, VM Shoba, A Choudhary, BK Wagner
Royal Society of Chemistry, 2022
12022
Target-based Screening and Structure-based Design Approaches to Develop Modulators of Protein–Protein Interactions
AE Modell, PS Arora
Inhibitors of Protein–Protein Interactions 17, 40, 2020
2020
Fragment-Based Approaches to Target Underutilized Pockets on Proteins
AE Modell
New York University, 2020
2020
Rationally designed protein domain mimics to inhibit recalcitrant protein-protein interactions
A Modell, D Rooklin, Y Zhang, P Arora
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
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