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Srinivas Chamakuri
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
EA Bowling, JH Wang, F Gong, W Wu, NJ Neill, IS Kim, S Tyagi, ...
Cell 184 (2), 384-403. e21, 2021
1112021
Small molecule modulators of protein–protein interactions: selected case studies
M Aeluri, S Chamakuri, B Dasari, SKR Guduru, R Jimmidi, S Jogula, ...
Chemical reviews 114 (9), 4640-4694, 2014
992014
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors
S Chamakuri, S Lu, MN Ucisik, KM Bohren, YC Chen, HC Du, JC Faver, ...
Proceedings of the National Academy of Sciences 118 (36), e2111172118, 2021
462021
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis
P Kandel, F Semerci, R Mishra, W Choi, A Bajic, D Baluya, LH Ma, ...
Proceedings of the National Academy of Sciences 119 (13), e2023784119, 2022
352022
Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production
DWY Prashi Jain, Idris O. Raji, Srinivas Chamakuri, Kevin R. MacKenzie ...
Journal of Organic Chemistry 84 (10), 6040-6064, 2019
29*2019
AlCl3-induced (hetero) arylation of thienopyrimidine ring: a new synthesis of 4-substituted thieno [2, 3-d] pyrimidines
KS Kumar, S Chamakuri, P Vishweshwar, J Iqbal, M Pal
Tetrahedron Letters 51 (25), 3269-3273, 2010
282010
Solution-phase Fmoc-based peptide synthesis for DNA-encoded chemical libraries: Reaction conditions, protecting group strategies, and pitfalls
OBC Monty, N Simmons, S Chamakuri, MM Matzuk, DW Young
ACS Combinatorial Science 22 (12), 833-843, 2020
172020
Tetrahydroquinoline-Derived Macrocyclic Toolbox: The Discovery of Antiangiogenesis Agents in Zebrafish Assay
SK Reddy Guduru, S Chamakuri, G Chandrasekar, SS Kitambi, P Arya
ACS Medicinal Chemistry Letters 4 (7), 666-670, 2013
17*2013
Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells
SA Moghadasi, MA Esler, Y Otsuka, JT Becker, SN Moraes, CB Anderson, ...
MBio 13 (3), e00784-22, 2022
162022
Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library
S Chamakuri, MK Chung, ELG Samuel, KA Tran, YC Chen, P Nyshadham, ...
Bioorganic & Medicinal Chemistry 48, 116387, 2021
102021
A modular approach to build macrocyclic diversity in aminoindoline scaffolds identifies antiangiogenesis agents from a zebrafish assay
S Chamakuri, SKR Guduru, S Pamu, G Chandrasekar, SS Kitambi, P Arya
European Journal of Organic Chemistry 2013 (19), 3959-3964, 2013
102013
Practical and scalable synthesis of orthogonally protected-2-substituted chiral piperazines
S Chamakuri, MM Shah, DCH Yang, C Santini, DW Young
Organic & Biomolecular Chemistry 18 (43), 8844-8849, 2020
82020
Oleic acid triggers hippocampal neurogenesis by binding to TLX/NR2E1
P Kandel, F Semerci, A Bajic, D Baluya, LH Ma, K Chen, A Cao, ...
bioRxiv, 2020.10. 28.359810, 2020
72020
Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons
S Jogula, AR Soorneedi, J Gaddam, S Chamakuri, GS Deora, ...
European Journal of Medicinal Chemistry 135, 110-116, 2017
52017
A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1, 2-Diamines
S Chamakuri, SA Tang, KA Tran, SKR Guduru, PK Bolin, KR MacKenzie, ...
Molecules 27 (11), 3419, 2022
42022
Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1
S Holmes, P Jain, KG Rodriguez, J Williams, Z Yu, C Cerda-Smith, ...
ACS Medicinal Chemistry Letters 15 (1), 107-115, 2024
22024
Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles
AB Viveki, TM Mansfield, KA Tran, E Lenkeit, KR MacKenzie, DW Young, ...
Chemistry–A European Journal 29 (55), e202301888, 2023
12023
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors
R Jimmidi, S Chamakuri, S Lu, MN Ucisik, PJ Chen, KM Bohren, ...
Communications Chemistry 6 (1), 164, 2023
12023
Regio-and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Macrocyclic Diversity
S Chamakuri, S Jogula, P Arya
ACS Combinatorial Science 17 (8), 437-441, 2015
12015
Expanding Complex Morpholines Using Systematic Chemical Diversity
SA Tang, A Fults, SR Boyd, N Gattu, KA Tran, J Fan, KR MacKenzie, ...
Organic Letters, 2024
2024
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