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Vittal Shivva
Vittal Shivva
Senior Scientist at Genentech
Verified email at gene.com
Title
Cited by
Cited by
Year
Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high‐performance liquid chromatography and its application to a pharmacokinetic study
S Vittal, NR Shitut, TR Kumar, MCA Vinu, R Mullangi, NR Srinivas
Biomedical Chromatography 20 (11), 1252-1259, 2006
682006
The Population Pharmacokinetics of d-β-hydroxybutyrate Following Administration of (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
V Shivva, PJ Cox, K Clarke, RL Veech, IG Tucker, SB Duffull
The AAPS journal 18, 678-688, 2016
642016
An approach for identifiability of population pharmacokinetic–pharmacodynamic models
V Shivva, J Korell, IG Tucker, SB Duffull
CPT: pharmacometrics & systems pharmacology 2 (6), 1-9, 2013
482013
Highly sensitive method for the determination of omeprazole in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: application to a clinical …
S Vittal, R Ganneboina, B Layek, RK Trivedi, KK Hotha, DV Bharathi, ...
Biomedical Chromatography 23 (4), 390-396, 2009
232009
An In Silico Knockout Model for Gastrointestinal Absorption Using a Systems Pharmacology Approach - Development and Application for Ketones
V Shivva, IG Tucker, SB Duffull
PLoS ONE 11 (9), 1-17, 2016
92016
Parameterisation affects identifiability of population models
V Shivva, J Korell, IG Tucker, SB Duffull
Journal of pharmacokinetics and pharmacodynamics 41, 81-86, 2014
82014
Chiral bioanalysis of torcetrapib enantiomers in hamster plasma by normal-phase liquid chromatography and detection by atmospheric pressure chemical ionization tandem mass …
RK Trivedi, B Layek, TS Kumar, S Vittal, R Ganneboina, PK Dubey, ...
Journal of Chromatography B 860 (2), 227-234, 2007
82007
Novel anti-LY6G6D/CD3 T-cell–dependent bispecific antibody for the treatment of colorectal cancer
P Wang, LL Sun, R Clark, M Hristopoulos, CPC Chiu, M Dillon, WY Lin, ...
Molecular Cancer Therapeutics 21 (6), 974-985, 2022
62022
Species difference in the in vitro and in vivo metabolism of amtolmetin guacil
KK Hotha, VB Dasari, AN Shaik, M Syed, V Shivva, RK Lakshmanarao, ...
Arzneimittelforschung 60 (11), 667-674, 2010
62010
Direct Tie2 Agonists Stabilize Vasculature for the Treatment of Diabetic Macular Edema
NJ Agard, G Zhang, J Ridgeway, DM Dicara, PY Chu, R Ohri, S Sanowar, ...
Translational Vision Science & Technology 11 (10), 27-27, 2022
52022
Antibody format and serum disposition govern ocular pharmacokinetics of intravenously administered protein therapeutics
V Shivva, CA Boswell, H Rafidi, RF Kelley, AV Kamath, SR Crowell
Frontiers in Pharmacology 12, 601569, 2021
52021
Safety, tolerability, pharmacokinetic and pharmacodynamic profile of multiple-doses of DRL-17822, a potent cholesteryl ester transfer protein inhibitor in healthy male subjects
MR Dasari, A Bapat, S Vittal, M Tippana, S Hasham, S Alikunju, ...
Circulation 122 (suppl_21), A13981-A13981, 2010
42010
Complex PK-PD of an engineered IL-15/IL-15Rα–Fc fusion protein in cynomolgus monkeys: QSP modeling of lymphocyte dynamics
D Lu, R Yadav, P Holder, E Chiang, S Sanjabi, V Poon, M Bernett, ...
European Journal of Pharmaceutical Sciences 186, 106450, 2023
32023
Evolution of preclinical characterization and insights into clinical pharmacology of checkpoint inhibitors approved for cancer immunotherapy
S Kasichayanula, S Mandlekar, V Shivva, M Patel, S Girish
Clinical and Translational Science 15 (8), 1818-1837, 2022
32022
Il15/il15r alpha heterodimeric fc-fusion proteins for the treatment of cancer
AJP Ungewickell, V Shivva, R Yadav
US Patent App. 17/814,456, 2023
12023
In vivo reoxidation kinetics of free thiols in multiple domains of IgG1 antibodies in rats
MT Kim, M Lechmann, S Rajan, V Shivva, A Lee, Y Chen, DD Weis
Journal of Pharmaceutical Sciences 110 (5), 1989-1996, 2021
12021
Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates
V Shivva, M Fink, PJ Lowe
Journal of Pharmacokinetics and Pharmacodynamics 48, 295-303, 2021
12021
Improving priors for human mAb linear PK parameters by using half-lives from pre-clinical species
V Shivva, PJ Lowe, M Fink
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 43, S82-S82, 2016
12016
Safety and tolerability of single ascending doses of DRL-17822, a potent CETP inhibitor, in healthy male subjects
A Bapat, M Rao, S Vittal, T Mangapathiraju, S Hasham, S Sai, S Alikunju, ...
Diabetes 59, A194-A195, 2010
12010
Preclinical and translational pharmacology of afucosylated anti‐CCR8 antibody for depletion of tumour‐infiltrating regulatory T cells
G Gampa, P Spinosa, J Getz, Y Zhong, W Halpern, E Esen, J Davies, ...
British Journal of Pharmacology, 2024
2024
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