Carlo Spirli
Carlo Spirli
Associate Professor of Medicine, Yale University
Verified email at yale.edu
TitleCited byYear
Pathophysiology of cholangiopathies
M Strazzabosco, L Fabris, C Spirli
Journal of clinical gastroenterology 39 (4), S90-S102, 2005
1632005
Effects of angiogenic factor overexpression by human and rodent cholangiocytes in polycystic liver diseases
L Fabris, M Cadamuro, R Fiorotto, T Roskams, C Spirlì, S Melero, ...
Hepatology 43 (5), 1001-1012, 2006
1312006
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes
C Spirlì, L Fabris, E Duner, R Fiorotto, G Ballardini, T Roskams, ...
Gastroenterology 124 (3), 737-753, 2003
1262003
Proinflammatory cytokines inhibit secretion in rat bile duct epithelium
C Spirlı̀, MH Nathanson, R Fiorotto, E Duner, LA Denson, JM Sanz, ...
Gastroenterology 121 (1), 156-169, 2001
1232001
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2−/− mice
E Halilbasic, R Fiorotto, P Fickert, HU Marschall, T Moustafa, C Spirli, ...
Hepatology 49 (6), 1972-1981, 2009
1182009
Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling
L Fabris, M Cadamuro, M Guido, C Spirli, R Fiorotto, M Colledan, G Torre, ...
The American journal of pathology 171 (2), 641-653, 2007
1172007
Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion
R Fiorotto, C Spirlì, L Fabris, M Cadamuro, L Okolicsanyi, M Strazzabosco
Gastroenterology 133 (5), 1603-1613, 2007
1092007
Pathophysiology of the intrahepatic biliary epithelium
M Strazzabosco, C Spirlì, L Okolicsanyi
Journal of gastroenterology and hepatology 15 (3), 244-253, 2000
1022000
Defective regulation of cholangiocyte Cl−/HCO [overthree] and Na+/H+ exchanger activities in primary biliary cirrhosis
S Melero, C Spirlı, A Zsembery, JF Medina, RE Joplin, E Duner, M Zuin, ...
Hepatology 35 (6), 1513-1521, 2002
862002
Platelet‐derived growth factor‐D and Rho GTPases regulate recruitment of cancer‐associated fibroblasts in cholangiocarcinoma
M Cadamuro, G Nardo, S Indraccolo, L Dall'Olmo, L Sambado, L Moserle, ...
Hepatology 58 (3), 1042-1053, 2013
842013
Mammalian target of rapamycin regulates vascular endothelial growth factor–dependent liver cyst growth in polycystin‐2–defective mice
C Spirli, S Okolicsanyi, R Fiorotto, L Fabris, M Cadamuro, S Lecchi, X Tian, ...
Hepatology 51 (5), 1778-1788, 2010
812010
Loss of CFTR affects biliary epithelium innate immunity and causes TLR4–NF-κB—mediated inflammatory response in mice
R Fiorotto, R Scirpo, M Trauner, L Fabris, R Hoque, C Spirli, ...
Gastroenterology 141 (4), 1498-1508. e5, 2011
792011
ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice
C Spirli, S Okolicsanyi, R Fiorotto, L Fabris, M Cadamuro, S Lecchi, X Tian, ...
Gastroenterology 138 (1), 360-371. e7, 2010
762010
Correction of CFTR malfunction and stimulation of Ca2+‐activated Cl channels restore HCO secretion in cystic fibrosis bile ductular cells
Á Zsembery, W Jessner, G Sitter, C Spirlí, M Strazzabosco, J Graf
Hepatology 35 (1), 95-104, 2002
682002
Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice
R Fiorotto, A Raizner, CM Morell, B Torsello, R Scirpo, L Fabris, C Spirli, ...
Journal of hepatology 59 (1), 124-130, 2013
672013
Na+‐dependent and ‐independent Cl/HCO exchange mediate cellular HCO transport in cultured human intrahepatic bile duct cells
M Strazzabosco, R Joplin, A Zsembery, L Wallace, C Spirli, L Fabris, ...
Hepatology 25 (4), 976-985, 1997
621997
Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis
F Marra, R DeFranco, G Robino, E Novo, E Efsen, S Pastacaldi, E Zamara, ...
World journal of gastroenterology: WJG 11 (32), 4931, 2005
582005
Epithelial expression of angiogenic growth factors modulate arterial vasculogenesis in human liver development
L Fabris, M Cadamuro, L Libbrecht, P Raynaud, C Spirlì, R Fiorotto, ...
Hepatology 47 (2), 719-728, 2008
562008
Purinergic regulation of acid/base transport in human and rat biliary epithelial cell lines
Á Zsembery, C Spirlì, A Granato, NF LaRusso, L Okolicsanyi, G Crepaldi, ...
Hepatology 28 (4), 914-920, 1998
551998
Diferentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation
M Strazzabosco, R Fiorotto, S Melero, S Glaser, H Francis, C Spirli, ...
Hepatology 50 (1), 244-252, 2009
542009
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