Jacintha O'Sullivan
Jacintha O'Sullivan
Professor in Translational Oncology, Trinity College Dublin
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Heterogeneity of tumor-induced gene expression changes in the human metabolic network
J Hu, JW Locasale, JH Bielas, J O'sullivan, K Sheahan, LC Cantley, ...
Nature biotechnology 31 (6), 522-529, 2013
Chromosomal instability in ulcerative colitis is related to telomere shortening
JN O'Sullivan, MP Bronner, TA Brentnall, JC Finley, WT Shen, S Emerson, ...
Nature genetics 32 (2), 280-284, 2002
Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer
LM Wang, D Kevans, H Mulcahy, J O'Sullivan, D Fennelly, J Hyland, ...
The American journal of surgical pathology 33 (1), 134-141, 2009
Synovial tissue hypoxia and inflammation in vivo
CT Ng, M Biniecka, A Kennedy, J McCormick, O Fitzgerald, B Bresnihan, ...
Annals of the rheumatic diseases 69 (7), 1389-1395, 2010
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue
RD Kennedy, M Bylesjo, P Kerr, T Davison, JM Black, EW Kay, RJ Holt, ...
Journal of Clinical Oncology 29 (35), 4620-4626, 2011
Dysregulated bioenergetics: a key regulator of joint inflammation
M Biniecka, M Canavan, T McGarry, W Gao, J McCormick, S Cregan, ...
Annals of the rheumatic diseases 75 (12), 2192-2200, 2016
Angiogenesis and blood vessel stability in inflammatory arthritis
A Kennedy, CT Ng, M Biniecka, T Saber, C Taylor, J O'Sullivan, DJ Veale, ...
Arthritis & Rheumatism 62 (3), 711-721, 2010
Overexpression of the microRNA miR‐433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells
K Weiner‐Gorzel, E Dempsey, M Milewska, A McGoldrick, V Toh, A Walsh, ...
Cancer medicine 4 (5), 745-758, 2015
Targeting hallmarks of cancer to enhance radiosensitivity in gastrointestinal cancers
AM Buckley, N Lynam-Lennon, H O’Neill, J O’Sullivan
Nature reviews Gastroenterology & hepatology 17 (5), 298-313, 2020
Clusterin biogenesis is altered during apoptosis in the regressing rat ventral prostate
J Lakins, SAL Bennett, JH Chen, JM Arnold, C Morrissey, P Wong, ...
Journal of Biological Chemistry 273 (43), 27887-27895, 1998
Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer
AJ Michielsen, AE Hogan, J Marry, M Tosetto, F Cox, JM Hyland, ...
PloS one 6 (11), e27944, 2011
Epithelial-mesenchymal transition (EMT) protein expression in a cohort of stage II colorectal cancer patients with characterized tumor budding and mismatch repair protein status
D Kevans, LM Wang, K Sheahan, J Hyland, D O’Donoghue, H Mulcahy, ...
International journal of surgical pathology 19 (6), 751-760, 2011
Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis
J O'Sullivan, L Whyte, J Drake, M Tenniswood
Cell Death & Differentiation 10 (8), 914-927, 2003
Emerging concepts linking obesity with the hallmarks of cancer
CL Donohoe, J Lysaght, J O'Sullivan, JV Reynolds
Trends in Endocrinology & Metabolism 28 (1), 46-62, 2017
Generation of an epigenetic signature by chronic hypoxia in prostate cells
JA Watson, CJ Watson, AM McCrohan, K Woodfine, M Tosetto, J McDaid, ...
Human molecular genetics 18 (19), 3594-3604, 2009
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett’s esophagus
C Palles, L Chegwidden, X Li, JM Findlay, G Farnham, FC Giner, ...
Gastroenterology 148 (2), 367-378, 2015
Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis
M Biniecka, E Fox, W Gao, CT Ng, DJ Veale, U Fearon, J O'Sullivan
Arthritis & Rheumatism 63 (8), 2172-2182, 2011
Oxidative damage in synovial tissue is associated with in vivo hypoxic status in the arthritic joint
M Biniecka, A Kennedy, U Fearon, CT Ng, DJ Veale, JN O'Sullivan
Annals of the rheumatic diseases 69 (6), 1172-1178, 2010
Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments
J O’Sullivan, J Lysaght, CL Donohoe, JV Reynolds
Nature reviews Gastroenterology & hepatology 15 (11), 699-714, 2018
Current targeted therapies in the treatment of advanced colorectal cancer: a review
A Moriarity, J O’Sullivan, J Kennedy, B Mehigan, P McCormick
Therapeutic advances in medical oncology 8 (4), 276-293, 2016
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