Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy JB Dinoso, SY Kim, AM Wiegand, SE Palmer, SJ Gange, L Cranmer, ... Proceedings of the National Academy of Sciences 106 (23), 9403-9408, 2009 | 542 | 2009 |
No evidence of severe acute respiratory syndrome–coronavirus 2 in semen of males recovering from coronavirus disease 2019 F Pan, X Xiao, J Guo, Y Song, H Li, DP Patel, AM Spivak, JP Alukal, ... Fertility and sterility 113 (6), 1135-1139, 2020 | 527 | 2020 |
Urinary tract infections: current and emerging management strategies AE Barber, JP Norton, AM Spivak, MA Mulvey Clinical infectious diseases 57 (5), 719-724, 2013 | 329 | 2013 |
A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1–infected adults on antiretroviral therapy AM Spivak, A Andrade, E Eisele, R Hoh, P Bacchetti, NN Bumpus, ... Clinical infectious diseases 58 (6), 883-890, 2014 | 227 | 2014 |
Novel latency reversal agents for HIV-1 cure AM Spivak, V Planelles Annual review of medicine 69, 421-436, 2018 | 181 | 2018 |
BIRC2/cIAP1 is a negative regulator of HIV-1 transcription and can be targeted by Smac mimetics to promote reversal of viral latency L Pache, MS Dutra, AM Spivak, JM Marlett, JP Murry, Y Hwang, ... Cell host & microbe 18 (3), 345-353, 2015 | 143 | 2015 |
A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation DB Reeves, ER Duke, TA Wagner, SE Palmer, AM Spivak, JT Schiffer Nature communications 9 (1), 4811, 2018 | 135 | 2018 |
HIV-1 eradication: early trials (and tribulations) AM Spivak, V Planelles Trends in molecular medicine 22 (1), 10-27, 2016 | 130 | 2016 |
CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells M Abdel-Mohsen, L Kuri-Cervantes, J Grau-Exposito, AM Spivak, RA Nell, ... Science translational medicine 10 (437), eaar6759, 2018 | 129 | 2018 |
Recommendations for measuring HIV reservoir size in cure-directed clinical trials M Abdel-Mohsen, D Richman, RF Siliciano, MC Nussenzweig, BJ Howell, ... Nature medicine 26 (9), 1339-1350, 2020 | 111 | 2020 |
Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4+ T Cells from Aviremic Patients AM Spivak, A Bosque, AH Balch, D Smyth, L Martins, V Planelles Antimicrobial agents and chemotherapy 59 (10), 5984-5991, 2015 | 99 | 2015 |
Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration AF Weil, D Ghosh, Y Zhou, L Seiple, MA McMahon, AM Spivak, ... Proceedings of the National Academy of Sciences 110 (6), E448-E457, 2013 | 93 | 2013 |
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation A Bosque, KA Nilson, AB Macedo, AM Spivak, NM Archin, ... Cell reports 18 (5), 1324-1334, 2017 | 88 | 2017 |
Dual TLR2 and TLR7 agonists as HIV latency-reversing agents AB Macedo, CL Novis, CM De Assis, ES Sorensen, P Moszczynski, ... JCI insight 3 (19), 2018 | 77 | 2018 |
HIV latency-reversing agents have diverse effects on natural killer cell function C Garrido, AM Spivak, N Soriano-Sarabia, MA Checkley, E Barker, J Karn, ... Frontiers in immunology 7, 356, 2016 | 59 | 2016 |
Modeling HIV-1 latency in primary T cells using a replication-competent virus LJ Martins, P Bonczkowski, AM Spivak, W De Spiegelaere, CL Novis, ... AIDS research and human retroviruses 32 (2), 187-193, 2016 | 59 | 2016 |
Seronegative HIV-1 infection: a review of the literature AM Spivak, ERM Sydnor, JN Blankson, JE Gallant Aids 24 (10), 1407-1414, 2010 | 56 | 2010 |
Spinal epidural abscess: current diagnosis and management G Pradilla, Y Nagahama, AM Spivak, A Bydon, D Rigamonti Current infectious disease reports 12, 484-491, 2010 | 55 | 2010 |
Pharmacological activation of non-canonical NF-κB signaling activates latent HIV-1 reservoirs in vivo L Pache, MD Marsden, P Teriete, AJ Portillo, D Heimann, JT Kim, ... Cell Reports Medicine 1 (3), 2020 | 41 | 2020 |
Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors AM Spivak, M Salgado, SA Rabi, KA O'Connell, JN Blankson Journal of virology 85 (19), 10399-10403, 2011 | 38 | 2011 |