| Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H W Chen, T Huang, X He, Q Meng, D You, L Bai, J Li, M Wu, R Li, Z Xie, ... Journal of biological chemistry 284 (16), 10627-10638, 2009 | 100 | 2009 |
| NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer X Liu, C Pei, S Yan, G Liu, G Liu, W Chen, Y Cui, Y Liu Tumor Biology 36, 1493-1502, 2015 | 75 | 2015 |
| Identification of the gene cluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471 L Cheng, W Chen, L Zhai, D Xu, T Huang, S Lin, X Zhou, Z Deng Molecular BioSystems 7 (3), 920-927, 2011 | 68 | 2011 |
| Identification and characterization of the pyridomycin biosynthetic gene cluster of Streptomyces pyridomyceticus NRRL B-2517 T Huang, Y Wang, J Yin, Y Du, M Tao, J Xu, W Chen, S Lin, Z Deng Journal of Biological Chemistry 286 (23), 20648-20657, 2011 | 64 | 2011 |
| Characterization of the tunicamycin gene cluster unveiling unique steps involved in its biosynthesis W Chen, D Qu, L Zhai, M Tao, Y Wang, S Lin, NPJ Price, Z Deng Protein & cell 1, 1093-1105, 2010 | 58 | 2010 |
| PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi R Li, G Liu, Z Xie, X He, W Chen, Z Deng, H Tan Molecular microbiology 75 (2), 349-364, 2010 | 55 | 2010 |
| polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis R Li, Z Xie, Y Tian, H Yang, W Chen, D You, G Liu, Z Deng, H Tan Microbiology 155 (6), 1819-1831, 2009 | 55 | 2009 |
| Activation of Natural Products Biosynthetic Pathways via a Protein Modification Level Regulation B Zhang, W Tian, S Wang, X Yan, X Jia, GK Pierens, W Chen, H Ma, ... ACS Chemical Biology 12 (7), 1732-1736, 2017 | 52 | 2017 |
| Natural and engineered biosynthesis of nucleoside antibiotics in Actinomycetes W Chen, J Qi, P Wu, D Wan, J Liu, X Feng, Z Deng Journal of Industrial Microbiology and Biotechnology 43 (2-3), 401-417, 2016 | 52 | 2016 |
| An unusual protector-protégé strategy for the biosynthesis of purine nucleoside antibiotics P Wu, D Wan, G Xu, G Wang, H Ma, T Wang, Y Gao, J Qi, X Chen, J Zhu, ... Cell chemical biology 24 (2), 171-181, 2017 | 41 | 2017 |
| Inhibition of NADPH oxidase protects against metastasis of human lung cancer by decreasing microRNA-21 S Yan, G Liu, C Pei, W Chen, P Li, Q Wang, X Jin, J Zhu, M Wang, X Liu Anti-cancer drugs 26 (4), 388-398, 2015 | 32 | 2015 |
| Genome sequences of three tunicamycin-producing Streptomyces strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396 JR Doroghazi, KS Ju, DW Brown, DP Labeda, Z Deng, WW Metcalf, ... Journal of bacteriology 193 (24), 7021-7022, 2011 | 32 | 2011 |
| Deciphering carbamoylpolyoxamic acid biosynthesis reveals unusual acetylation cycle associated with tandem reduction and sequential hydroxylation J Qi, D Wan, H Ma, Y Liu, R Gong, X Qu, Y Sun, Z Deng, W Chen Cell Chemical Biology 23 (8), 935-944, 2016 | 31 | 2016 |
| Engineering of an industrial polyoxin producer for the rational production of hybrid peptidyl nucleoside antibiotics L Zhai, S Lin, D Qu, X Hong, L Bai, W Chen, Z Deng Metabolic Engineering 14 (4), 388-393, 2012 | 29 | 2012 |
| Characterization of the aurantimycin biosynthetic gene cluster and enhancing its production by manipulating two pathway-specific activators in Streptomyces aurantiacus JA 4570 H Zhao, L Wang, D Wan, J Qi, R Gong, Z Deng, W Chen Microbial Cell Factories 15, 1-12, 2016 | 28 | 2016 |
| Comparative Investigation into Formycin A and Pyrazofurin A Biosynthesis Reveals Branch Pathways for the Construction of C-Nucleoside Scaffolds M Zhang, P Zhang, G Xu, W Zhou, Y Gao, R Gong, YS Cai, H Cong, ... Applied and Environmental Microbiology 86 (2), e01971-19, 2020 | 25 | 2020 |
| Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090 Y Liu, R Gong, X Liu, P Zhang, Q Zhang, YS Cai, Z Deng, M Winkler, J Wu, ... Microbial Cell Factories 17, 1-10, 2018 | 24 | 2018 |
| Divergent biosynthesis of C-nucleoside minimycin and indigoidine in bacteria L Kong, G Xu, X Liu, J Wang, Z Tang, YS Cai, K Shen, W Tao, Y Zheng, ... Iscience 22, 430-440, 2019 | 23 | 2019 |
| Construction of an octosyl acid backbone catalyzed by a radical S-adenosylmethionine enzyme and a phosphatase in the biosynthesis of high-carbon sugar nucleoside antibiotics N He, P Wu, Y Lei, B Xu, X Zhu, G Xu, Y Gao, J Qi, Z Deng, G Tang, ... Chemical Science 8 (1), 444-451, 2017 | 22 | 2017 |
| Enhancement of the diversity of polyoxins by a thymine-7-hydroxylase homolog outside the polyoxin biosynthesis gene cluster C Zhao, T Huang, W Chen, Z Deng Applied and environmental microbiology 76 (21), 7343-7347, 2010 | 22 | 2010 |
