Elizabeth Brunk
Elizabeth Brunk
Assistant Professor at UNC Chapel Hill
Verified email at - Homepage
Cited by
Cited by
Recon 3D enables a three-dimensional view of gene variation in human metabolism
E Brunk, S Sahoo, DC Zielinski, A Altunkaya, N Mih, A Prlić, A Sastry, ...
Nature Biotechnology 36 (3), 272-281, 2018
iML1515, a knowledgebase that computes Escherichia coli traits
J Monk*, C Llyod*, E Brunk*, A Mih, N., Sastry, Z King, R Takeuchi, ...
Nature Biotechnology, 2017
Mixed quantum mechanical/molecular mechanical molecular dynamics simulations of biological systems in ground and electronically excited states
E Brunk, U Rothlisberger
Chemical reviews 115 (12), 6217-6263, 2015
NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling
S Chowdhry, C Zanca, U Rajkumar, T Koga, Y Diao, R Raviram, F Liu, ...
Nature 569 (7757), 570-575, 2019
Multi-omic data integration enables discovery of hidden biological regularities
A Ebrahim*, E Brunk*, J Tan*, EJ O’Brien, K Donghyuk, J Lerman, ...
Nature Communications 7 (doi:10.1038/ncomms13091), 2016
Model-driven discovery of underground metabolic functions in Escherichia coli
GI Guzmán*, J Utrilla*, S Nurk, E Brunk, JM Monk, A Ebrahim, BO Palsson, ...
Proceedings of the National Academy of Sciences 112 (3), 929-934, 2015
Directed Evolution of the Suicide Protein O6-Alkylguanine-DNA Alkyltransferase for Increased Reactivity Results in an Alkylated Protein with Exceptional Stability
B Mollwitz, E Brunk, S Schmitt, F Pojer, M Bannwarth, M Schiltz, ...
Biochemistry 51 (5), 986-994, 2012
Characterizing Strain Variation in Engineered E. coli Using a Multi-omics Based Workflow
E Brunk*, KJ George*, J Alonso-Gutierrez, M Thompson, E Baidoo, ...
Cell Systems, 2016
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Nature communications 9 (1), 3796, 2018
Mapping genetic variations to three-dimensional protein structures to enhance variant interpretation: a proposed framework
G Glusman, PW Rose, A Prlić, J Dougherty, JM Duarte, AS Hoffman, ...
Genome medicine 9, 1-10, 2017
Systems Biology of the Structural Proteome
E Brunk*, J Mih*, N, Monk, K Chen, Z Zhang, S Bliven, E O’Brien, ...
BMC Systems Biology, 2016
The Need for Integrated Approaches in Metabolic Engineering
A Lechner, E Brunk, JD Keasling
Cold Spring Harbor Perspectives, 2016
A streamlined ribosome profiling protocol for the characterization of microorganisms
H Latif, R Szubin, J Tan, E Brunk, A Lechner, K Zengler, BO Palsson
BioTechniques 58 (6), 329–332, 2015
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the phosphotransferase system
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Metabolic engineering 48, 233-242, 2018
Characterizing post-translational modifications in prokaryote metabolism using a multi-scale workflow
E Brunk, RL Chang, J Xia, H Hefzi, JT Yurkovich, D Kim, E Buckmiller, ...
PNAS, 2018
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Metabolic engineering 48, 82-93, 2018
Integrating computational methods to retrofit enzymes to synthetic pathways
E Brunk, M Neri, I Tavernelli, V Hatzimanikatis, U Rothlisberger
Biotechnology and bioengineering 109 (2), 572-582, 2012
ssbio: a Python framework for structural systems biology
N Mih, E Brunk, K Chen, E Catoiu, A Sastry, E Kavvas, JM Monk, Z Zhang, ...
Bioinformatics 34 (12), 2155-2157, 2018
Role of environment for catalysis of the DNA repair enzyme MutY
E Brunk, JS Arey, U Rothlisberger
Journal of the American Chemical Society 134 (20), 8608-8616, 2012
Multiple optimal phenotypes overcome redox and glycolytic intermediate metabolite imbalances in Escherichia coli pgi knockout evolutions
D McCloskey, S Xu, TE Sandberg, E Brunk, Y Hefner, R Szubin, AM Feist, ...
Applied and environmental microbiology 84 (19), e00823-18, 2018
The system can't perform the operation now. Try again later.
Articles 1–20