Length-dependent axo-terminal degeneration at the neuromuscular synapses of type II muscle in SOD1 mice C Tallon, KA Russell, S Sakhalkar, N Andrapallayal, MH Farah Neuroscience 312, 179-189, 2016 | 55 | 2016 |
Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug R Rais, KM Lemberg, L Tenora, ML Arwood, A Pal, J Alt, Y Wu, J Lam, ... Science Advances 8 (46), eabq5925, 2022 | 39 | 2022 |
Novel human neutral sphingomyelinase 2 inhibitors as potential therapeutics for Alzheimer’s disease M Šála, KR Hollinger, AG Thomas, RP Dash, C Tallon, V Veeravalli, ... Journal of medicinal chemistry 63 (11), 6028-6056, 2020 | 36 | 2020 |
Increased BACE1 activity inhibits peripheral nerve regeneration after injury C Tallon, E Rockenstein, E Masliah, MH Farah Neurobiology of disease 106, 147-157, 2017 | 24 | 2017 |
Beta secretase activity in peripheral nerve regeneration C Tallon, MH Farah Neural Regeneration Research 12 (10), 1565-1574, 2017 | 23 | 2017 |
Nipping disease in the bud: nSMase2 inhibitors as therapeutics in extracellular vesicle-mediated diseases C Tallon, KR Hollinger, A Pal, BJ Bell, R Rais, T Tsukamoto, KW Witwer, ... Drug Discovery Today 26 (7), 1656-1668, 2021 | 22 | 2021 |
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis KR Hollinger, A Sharma, C Tallon, L Lovell, AG Thomas, X Zhu, ... Nanotheranostics 6 (2), 126, 2022 | 20 | 2022 |
Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury C Tallon, S Picciolini, SW Yoo, AG Thomas, A Pal, J Alt, C Carlomagno, ... Biochemical Pharmacology 194, 114796, 2021 | 16 | 2021 |
Glutamine antagonist JHU-083 normalizes aberrant hippocampal glutaminase activity and improves cognition in APOE4 mice KR Hollinger, X Zhu, ES Khoury, AG Thomas, K Liaw, C Tallon, Y Wu, ... Journal of Alzheimer's Disease 77 (1), 437-447, 2020 | 16 | 2020 |
Dendrimer-2PMPA Delays Muscle Function Loss and Denervation in a Murine Model of Amyotrophic Lateral Sclerosis C Tallon, A Sharma, Z Zhang, AG Thomas, J Ng, X Zhu, A Donoghue, ... Neurotherapeutics 19 (1), 274-288, 2022 | 10 | 2022 |
Sowing the Seeds of Discovery: Tau-Propagation Models of Alzheimer’s Disease BJ Bell, MM Malvankar, C Tallon, BS Slusher ACS Chemical Neuroscience 11 (21), 3499-3509, 2020 | 10 | 2020 |
Pharmacological BACE inhibition improves axonal regeneration in nerve injury and disease models C Tallon, KL Marshall, ME Kennedy, LA Hyde, MH Farah Neurotherapeutics 17 (3), 973-988, 2020 | 10 | 2020 |
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice C Tallon, BJ Bell, A Sharma, A Pal, MM Malvankar, AG Thomas, SW Yoo, ... Pharmaceutics 14 (10), 2066, 2022 | 9 | 2022 |
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer’s disease mouse model C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ... Translational Neurodegeneration 12 (1), 56, 2023 | 2 | 2023 |
Effects of 6-Aminonicotinic Acid Esters on the Reprogrammed Epigenetic State of Distant Metastatic Pancreatic Carcinoma RD Gao, M Maeda, C Tallon, AP Feinberg, BS Slusher, T Tsukamoto ACS Medicinal Chemistry Letters 13 (12), 1892-1897, 2022 | 2 | 2022 |
Regulatory T cells reduce endothelial neutral sphingomyelinase 2 to prevent T‐cell migration into tumors P Akeus, L Szeponik, V Langenes, V Karlsson, P Sundström, ... European Journal of Immunology 51 (9), 2317-2329, 2021 | 2 | 2021 |
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer’s disease C Tallon, BJ Bell, MM Malvankar, P Deme, C Nogueras-Ortiz, E Eren, ... Research Square, 2023 | 1 | 2023 |
Inhibition of EV biogenesis reduces tau propagation in Alzheimer’s Disease mouse models M Huang, C Tallon, BJ Bell, D Kapogiannis, NJ Haughey, R Rais, ... Alzheimer's & Dementia 19, e078341, 2023 | | 2023 |
16th Clinical Trials on Alzheimer’s Disease (CTAD) Boston, MA (USA) October 24–27, 2023: Posters C Tallon, C Gajera, J Posakony, G Block, V Daggett J Prev Alzheimers Dis 10 (Suppl 1), 56–240, 2023 | | 2023 |
Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice M Huang, C Tallon, X Zhu, KDJ Huizar, S Picciolini, AG Thomas, L Tenora, ... Pharmaceutics 15 (9), 2364, 2023 | | 2023 |