Highly scalable generation of DNA methylation profiles in single cells RM Mulqueen, D Pokholok, SJ Norberg, KA Torkenczy, AJ Fields, D Sun, ... Nature biotechnology 36 (5), 428-431, 2018 | 237 | 2018 |
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data D Sun, X Guan, AE Moran, LY Wu, DZ Qian, P Schedin, MS Dai, ... Nature biotechnology 40 (4), 527-538, 2022 | 149 | 2022 |
Mesenchymal lineage heterogeneity underlies nonredundant functions of pancreatic cancer–associated fibroblasts EJ Helms, MW Berry, RC Chaw, CC DuFort, D Sun, MK Onate, C Oon, ... Cancer discovery 12 (2), 484-501, 2022 | 124 | 2022 |
Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas, TM Beer, ... European urology 76 (5), 562-571, 2019 | 124 | 2019 |
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance JJ Alumkal, D Sun, E Lu, TM Beer, GV Thomas, E Latour, R Aggarwal, ... Proceedings of the National Academy of Sciences 117 (22), 12315-12323, 2020 | 99 | 2020 |
RNA-seq from archival FFPE breast cancer samples: molecular pathway fidelity and novel discovery ND Pennock, S Jindal, W Horton, D Sun, J Narasimhan, L Carbone, ... BMC medical genomics 12, 1-18, 2019 | 54 | 2019 |
BET bromodomain inhibition blocks an AR-repressed, E2F1-activated treatment-emergent neuroendocrine prostate cancer lineage plasticity program DH Kim, D Sun, WK Storck, KW Leng, C Jenkins, DJ Coleman, ... Clinical cancer research 27 (17), 4923, 2021 | 43 | 2021 |
Postpartum breast cancer has a distinct molecular profile that predicts poor outcomes S Jindal, ND Pennock, D Sun, W Horton, MK Ozaki, J Narasimhan, ... Nature communications 12 (1), 6341, 2021 | 27 | 2021 |
BET bromodomain inhibition blocks the function of a critical AR-independent master regulator network in lethal prostate cancer DJ Coleman, L Gao, CJ King, J Schwartzman, J Urrutia, A Sehrawat, ... Oncogene 38 (28), 5658-5669, 2019 | 27 | 2019 |
Pharmacologic Targeting of Mcl-1 Induces Mitochondrial Dysfunction and Apoptosis in B-Cell Lymphoma Cells in a TP53-and BAX-Dependent Manner T Liu, V Lam, E Thieme, D Sun, X Wang, F Xu, L Wang, OV Danilova, ... Clinical Cancer Research 27 (17), 4910-4922, 2021 | 26 | 2021 |
Alternative splicing of LSD1+ 8a in neuroendocrine prostate cancer is mediated by SRRM4 DJ Coleman, DA Sampson, A Sehrawat, A Kumaraswamy, D Sun, ... Neoplasia 22 (6), 253-262, 2020 | 24 | 2020 |
A community challenge for inferring genetic predictors of gene essentialities through analysis of a functional screen of cancer cell lines M Gönen, BA Weir, GS Cowley, F Vazquez, Y Guan, A Jaiswal, ... Cell systems 5 (5), 485-497. e3, 2017 | 24 | 2017 |
A cancer cell–intrinsic GOT2–PPARδ axis suppresses antitumor immunity J Abrego, H Sanford-Crane, C Oon, X Xiao, CB Betts, D Sun, S Nagarajan, ... Cancer discovery 12 (10), 2414-2433, 2022 | 23 | 2022 |
Discovering cooperative biomarkers for heterogeneous complex disease diagnoses D Sun, X Ren, E Ari, T Korcsmaros, P Csermely, LY Wu Briefings in bioinformatics 20 (1), 89-101, 2019 | 17 | 2019 |
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity TC Westbrook, X Guan, E Rodansky, D Flores, CJ Liu, AM Udager, ... Nature communications 13 (1), 5345, 2022 | 16 | 2022 |
Mammary collagen is under reproductive control with implications for breast cancer Q Guo, D Sun, AS Barrett, S Jindal, ND Pennock, MW Conklin, Z Xia, ... Matrix Biology 105, 104-126, 2022 | 14 | 2022 |
Copy number loss of 17q22 is associated with enzalutamide resistance and poor prognosis in metastatic castration-resistant prostate cancer X Guan, D Sun, E Lu, JA Urrutia, RE Reiter, M Rettig, CP Evans, P Lara Jr, ... Clinical Cancer Research 26 (17), 4616-4624, 2020 | 10 | 2020 |
CDK9 inhibition induces epigenetic reprogramming revealing strategies to circumvent resistance in lymphoma E Thieme, N Bruss, D Sun, EC Dominguez, D Coleman, T Liu, C Roleder, ... Molecular Cancer 22 (1), 64, 2023 | 8 | 2023 |
CEA: Combination-based gene set functional enrichment analysis D Sun, Y Liu, XS Zhang, LY Wu Scientific Reports 8 (1), 13085, 2018 | 4 | 2018 |
Network Refinement: Denoising complex networks for better community detection J Yu, J Leng, D Sun, LY Wu Physica A: Statistical Mechanics and its Applications 617, 128681, 2023 | 3 | 2023 |