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Cynthia M Simbulan-Rosenthal, Ph.D
Cynthia M Simbulan-Rosenthal, Ph.D
Professor, Georgetown University School of Medicine
Verified email at georgetown.edu - Homepage
Title
Cited by
Cited by
Year
Poly (ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced parkinsonism
AS Mandir, S Przedborski, V Jackson-Lewis, ZQ Wang, ...
Proceedings of the National Academy of Sciences 96 (10), 5774-5779, 1999
4791999
Transient poly (ADP-ribosyl) ation of nuclear proteins and role of poly (ADP-ribose) polymerase in the early stages of apoptosis
CM Simbulan-Rosenthal, DS Rosenthal, S Iyer, AH Boulares, ...
Journal of biological chemistry 273 (22), 13703-13712, 1998
3331998
Misregulation of gene expression in primary fibroblasts lacking poly (ADP-ribose) polymerase
CM Simbulan-Rosenthal, DH Ly, DS Rosenthal, G Konopka, RB Luo, ...
Proceedings of the National Academy of Sciences 97 (21), 11274-11279, 2000
1862000
The expression of poly (ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex
CM Simbulan-Rosenthal, DS Rosenthal, H Hilz, R Hickey, L Malkas, ...
Biochemistry 35 (36), 11622-11633, 1996
1741996
Roles of poly (ADP-ribosyl) ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1
ME Smulson, CM Simbulan-Rosenthal, AH Boulares, A Yakovlev, ...
Advances in Enzyme Regulation 40 (1), 183-215, 2000
1682000
Chromosomal aberrations in PARP−/− mice: Genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA
CM Simbulan-Rosenthal, BR Haddad, DS Rosenthal, Z Weaver, ...
Proceedings of the National Academy of Sciences 96 (23), 13191-13196, 1999
1601999
Sulfur mustard induces markers of terminal differentiation and apoptosis in keratinocytes via a Ca2+-calmodulin and caspase-dependent pathway
DS Rosenthal, CMG Simbulan-Rosenthal, S Iyer, ME Smulson, ...
Journal of Investigative Dermatology 111 (1), 64-71, 1998
1561998
Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication
CM Simbulan-Rosenthal, DS Rosenthal, S Iyer, H Boulares, ME Smulson
Mol Cell Biochem 193 (1-2), 137-148, 1999
1421999
The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosis
H Stöppler, MC Stöppler, E Johnson, CM Simbulan-Rosenthal, ...
Oncogene 17 (10), 1207-1214, 1998
1351998
Poly (ADP-ribosyl) ation of p53 during apoptosis in human osteosarcoma cells
CM Simbulan-Rosenthal, DS Rosenthal, RB Luo, ME Smulson
Cancer Research 59 (9), 2190-2194, 1999
1341999
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells …
CM Simbulan-Rosenthal, DS Rosenthal, RB Luo, R Samara, LA Espinoza, ...
Oncogene 22 (52), 8460-8471, 2003
1272003
Irreversible binding of poly (ADP) ribose polymerase cleavage product to DNA ends revealed by atomic force microscopy: possible role in apoptosis
ME Smulson, D Pang, M Jung, A Dimtchev, S Chasovskikh, A Spoonde, ...
Cancer Research 58 (16), 3495-3498, 1998
1241998
Regulation of the expression or recruitment of components of the DNA synthesome by poly (ADP-ribose) polymerase
CM Simbulan-Rosenthal, DS Rosenthal, AH Boulares, RJ Hickey, ...
Biochemistry 37 (26), 9363-9370, 1998
1231998
Intact cell evidence for the early synthesis, and subsequent late apopain-mediated suppression, of poly (ADP-ribose) during apoptosis
DS Rosenthal, R Ding, CMG Simbulan-Rosenthal, JP Vaillancourt, ...
Experimental Cell Research 232 (2), 313-321, 1997
1161997
A novel in vivo post‐translational modification of p53 by PARP‐1 in MPTP‐induced parkinsonism
AS Mandir, CM Simbulan‐Rosenthal, MF Poitras, JR Lumpkin, ...
Journal of Neurochemistry 83 (1), 186-192, 2002
1072002
Identification of poly (ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax protein
MG Anderson, KES Scoggin, CM Simbulan-Rosenthal, JA Steadman
Journal of Virology 74 (5), 2169-2177, 2000
972000
Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association
CM Simbulan, M Suzuki, S Izuta, T Sakurai, E Savoysky, K Kojima, ...
Journal of Biological Chemistry 268 (1), 93-99, 1993
961993
Inhibition of DNA primase by sphingosine and its analogues parallels with their growth suppression of cultured human leukemic cells
K Tamiya-Koizumi, T Murate, M Suzuki, CM Simbulan, M Nakagawa, ...
Biochem Mol Biol Int 41 (6), 1179-1189, 1997
911997
Role of DNAS1L3 in Ca2+-and Mg2+-dependent cleavage of DNA into oligonucleosomal and high molecular mass fragments
AG Yakovlev, G Wang, BA Stoica, CM Simbulan-Rosenthal, ME Smulson, ...
Nucleic Acids Research 27 (9), 1999-2005, 1999
851999
Expression of dominant-negative Fas-associated death domain blocks human keratinocyte apoptosis and vesication induced by sulfur mustard
DS Rosenthal, A Velena, FP Chou, R Schlegel, R Ray, B Benton, ...
Journal of Biological Chemistry 278 (10), 8531-8540, 2003
832003
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