A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE JR Godin, P Roy, M Quadri, D Bagdas, W Toma, R Narendrula-Kotha, ... Brain, behavior, and immunity 87, 286-300, 2020 | 41 | 2020 |
Dissection of N, N-diethyl-N′-phenylpiperazines as α7 nicotinic receptor silent agonists M Quadri, RL Papke, NA Horenstein Bioorganic & medicinal chemistry 24 (2), 286-293, 2016 | 39 | 2016 |
Bis (ammonio) alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity C Matera, L Flammini, M Quadri, V Vivo, V Ballabeni, U Holzgrabe, ... European journal of medicinal chemistry 75, 222-232, 2014 | 37 | 2014 |
Cracking the betel nut: cholinergic activity of Areca alkaloids and related compounds NA Horenstein, M Quadri, C Stokes, M Shoaib, RL Papke Nicotine & Tobacco Research, 1-8, 2017 | 33 | 2017 |
Allosteric agonism of α7 nicotinic acetylcholine receptors A Gulsevin, RL Papke, C Stokes, G Sumanta, GA Thakur, M Quadri, ... Molecular Pharmacology, mol. 119.115758, 2019 | 26* | 2019 |
The antinociceptive and anti-inflammatory properties of the α7 nAChR weak partial agonist p-CF3 N, N-diethyl-N′-phenylpiperazine M Quadri, D Bagdas, W Toma, C Stokes, NA Horenstein, MI Damaj, ... Journal of Pharmacology and Experimental Therapeutics 367 (2), 203-214, 2018 | 24 | 2018 |
Macroscopic and microscopic activation of α7 nicotinic acetylcholine receptors by the structurally unrelated ago-PAMs B-973B and GAT107 M Quadri, S Garai, GA Thakur, C Stokes, A Gulsevin, NA Horenstein, ... Society for Neuroscience, 2018 | 22* | 2018 |
Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and … M Quadri, C Matera, A Silnović, MC Pismataro, NA Horenstein, C Stokes, ... ChemMedChem 12 (16), 1335-1348, 2017 | 19 | 2017 |
Sulfonium as a surrogate for ammonium: a new α7 nicotinic acetylcholine receptor partial agonist with desensitizing activity M Quadri, C Stokes, A Gulsevin, ACJ Felts, KA Abboud, RL Papke, ... Journal of medicinal chemistry 60 (18), 7928-7934, 2017 | 15 | 2017 |
Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype C Matera, M Quadri, M Sciaccaluga, DY Pomè, F Fasoli, M De Amici, ... European Journal of Medicinal Chemistry 108, 392-405, 2016 | 15 | 2016 |
Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor … MC Pismataro, NA Horenstein, C Stokes, M Quadri, M De Amici, ... European journal of medicinal chemistry 205, 112669, 2020 | 14 | 2020 |
Selective agonists and antagonists of α9 versus α7 nicotinic acetylcholine receptors RL Papke, H Andleeb, C Stokes, M Quadri, NA Horenstein ACS chemical neuroscience 13 (5), 624-637, 2022 | 11 | 2022 |
Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy AB Murray, M Quadri, H Li, R McKenna, NA Horenstein Carbohydrate research 476, 65-70, 2019 | 10 | 2019 |
Novel 5-(quinuclidin-3-ylmethyl)-1, 2, 4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation M Quadri, A Silnović, C Matera, NA Horenstein, C Stokes, M De Amici, ... European journal of medicinal chemistry 160, 207-228, 2018 | 10 | 2018 |
Silent agonists for α7 nicotinic acetylcholine receptors RL Papke, M Quadri, A Gulsevin Pharmacological Research 190, 106736, 2023 | 7 | 2023 |
Nicotinic acetylcholine receptor silent agonists NA Horenstein, RL Papke, M Quadri US Patent 10,662,191, 2020 | 2 | 2020 |
Determination of acid dissociation constants of poorly water-soluble nicotinic ligands by means of electrophoretic and potentiometric techniques G Roda, C Dallanoce, V Gambaro, G Grazioso, V Liberti, C Matera, ... PHARMACEUTICA ANALYTICA ACTA 6 (7), 1-5, 2015 | 2 | 2015 |
A convenient synthesis of 4-(2-hydroxyethyl) indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors C Matera, M Quadri, S Pelucchi, M De Amici, C Dallanoce Monatshefte für Chemie-Chemical Monthly 145, 1139-1144, 2014 | 2 | 2014 |
Nicotinic acetylcholine receptor silent agonists NA Horenstein, RL Papke, M Quadri US Patent App. 17/370,634, 2021 | 1 | 2021 |
Nicotinic acetylcholine receptor silent agonists NA Horenstein, RL Papke, M Quadri US Patent 11,155,551, 2021 | 1 | 2021 |