Hans-Ulrich Klein
Hans-Ulrich Klein
Columbia University Medical Center
Verified email at columbia.edu
Cited by
Cited by
Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
T Haferlach, Y Nagata, V Grossmann, Y Okuno, U Bacher, G Nagae, ...
Leukemia 28 (2), 241, 2014
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ...
Nature medicine 18 (4), 605, 2012
Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in …
A Kohlmann, V Grossmann, HU Klein, S Schindela, T Weiss, B Kazak, ...
Journal of clinical oncology 28 (24), 3858-3865, 2010
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype
V Grossmann, E Tiacci, AB Holmes, A Kohlmann, MP Martelli, W Kern, ...
Blood 118 (23), 6153-6163, 2011
Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms
C Polprasert, I Schulze, MA Sekeres, H Makishima, B Przychodzen, ...
Cancer cell 27 (5), 658-670, 2015
Detection of significantly differentially methylated regions in targeted bisulfite sequencing data
K Hebestreit, M Dugas, HU Klein
Bioinformatics 29 (13), 1647-1653, 2013
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome
B Ng, CC White, HU Klein, SK Sieberts, C McCabe, E Patrick, J Xu, L Yu, ...
Nature neuroscience 20 (10), 1418, 2017
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease
S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ...
Nature Neuroscience 21 (6), 811, 2018
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an …
A Kohlmann, HU Klein, S Weissmann, S Bresolin, T Chaplin, H Cuppens, ...
Leukemia 25 (12), 1840, 2011
Multilineage dysplasia (MLD) in acute myeloid leukemia (AML) correlates with MDS-related cytogenetic abnormalities and a prior history of MDS or MDS/MPN but has no independent …
M Miesner, C Haferlach, U Bacher, T Weiss, K Macijewski, A Kohlmann, ...
Blood 116 (15), 2742-2751, 2010
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia
S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ...
Nature medicine 23 (1), 69, 2017
Multilineage dysplasia has no impact on biologic, clinicopathologic, and prognostic features of AML with mutated nucleophosmin (NPM1)
B Falini, K Macijewski, T Weiss, U Bacher, S Schnittger, W Kern, ...
Blood 115 (18), 3776-3786, 2010
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells
E Bolton-Gillespie, M Schemionek, HU Klein, S Flis, G Hoser, T Lange, ...
Blood 121 (20), 4175-4183, 2013
AML with translocation t (8; 16)(p11; p13) demonstrates unique cytomorphological, cytogenetic, molecular and prognostic features
T Haferlach, A Kohlmann, HU Klein, C Ruckert, M Dugas, PM Williams, ...
Leukemia 23 (5), 934, 2009
Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia
C Müller-Tidow, HU Klein, A Hascher, F Isken, L Tickenbrock, ...
Blood 116 (18), 3564-3571, 2010
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene
S Agrawal-Singh, F Isken, K Agelopoulos, HU Klein, NH Thoennissen, ...
Blood 119 (10), 2346-2357, 2012
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research
PL De Jager, Y Ma, C McCabe, J Xu, BN Vardarajan, D Felsky, HU Klein, ...
Scientific data 5, 180142, 2018
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
C Bartenhagen, HU Klein, C Ruckert, X Jiang, M Dugas
BMC bioinformatics 11 (1), 567, 2010
Tau activates transposable elements in Alzheimer’s disease
C Guo, HH Jeong, YC Hsieh, HU Klein, DA Bennett, PL De Jager, Z Liu, ...
Cell Reports 23 (10), 2874-2880, 2018
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding
T Schoofs, C Rohde, K Hebestreit, HU Klein, S Göllner, I Schulze, ...
Blood 121 (1), 178-187, 2013
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