| Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin MYF Tay, JE Fraser, WKK Chan, NJ Moreland, AP Rathore, C Wang, ... Antiviral research 99 (3), 301-306, 2013 | 363 | 2013 |
| Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance AL St. John, APS Rathore, H Yap, ML Ng, DD Metcalfe, SG Vasudevan, ... Proceedings of the National Academy of Sciences 108 (22), 9190-9195, 2011 | 250 | 2011 |
| Adaptive immune responses to primary and secondary dengue virus infections AL St. John, APS Rathore Nature Reviews Immunology 19 (4), 218-230, 2019 | 248 | 2019 |
| Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial JG Low, C Sung, L Wijaya, Y Wei, APS Rathore, S Watanabe, BH Tan, ... The Lancet infectious diseases 14 (8), 706-715, 2014 | 233 | 2014 |
| Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage AL St John, APS Rathore, B Raghavan, ML Ng, SN Abraham elife 2, e00481, 2013 | 187 | 2013 |
| Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model APS Rathore, PN Paradkar, S Watanabe, KH Tan, C Sung, JE Connolly, ... Antiviral research 92 (3), 453-460, 2011 | 185 | 2011 |
| Cross-reactive immunity among flaviviruses APS Rathore, AL St. John Frontiers in immunology 11, 334, 2020 | 144 | 2020 |
| Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation APS Rathore, ML Ng, SG Vasudevan Virology journal 10, 1-15, 2013 | 120 | 2013 |
| Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses APS Rathore, WAA Saron, T Lim, N Jahan, AL St. John Science Advances 5 (2), eaav3208, 2019 | 111 | 2019 |
| Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo APS Rathore, T Haystead, PK Das, A Merits, ML Ng, SG Vasudevan Antiviral research 103, 7-16, 2014 | 107 | 2014 |
| Dose-and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial S Watanabe, APS Rathore, C Sung, F Lu, YM Khoo, J Connolly, J Low, ... Antiviral research 96 (1), 32-35, 2012 | 105 | 2012 |
| Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE R Msallam, J Balla, APS Rathore, H Kared, B Malleret, WAA Saron, Z Liu, ... Science 370 (6519), 941-950, 2020 | 91 | 2020 |
| Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells WAA Saron, APS Rathore, L Ting, EE Ooi, J Low, SN Abraham, ... Science advances 4 (7), eaar4297, 2018 | 79 | 2018 |
| Dengue virus–elicited tryptase induces endothelial permeability and shock APS Rathore, CK Mantri, SAB Aman, A Syenina, J Ooi, CJ Jagaraj, ... The Journal of clinical investigation 129 (10), 4180-4193, 2019 | 76 | 2019 |
| The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model S Watanabe, KH Tan, APS Rathore, K Rozen-Gagnon, W Shuai, C Ruedl, ... Journal of virology 86 (10), 5508-5514, 2012 | 72 | 2012 |
| Japanese encephalitis virus neuropenetrance is driven by mast cell chymase JT Hsieh, APS Rathore, G Soundarajan, AL St. John Nature communications 10 (1), 706, 2019 | 71 | 2019 |
| Early insights into immune responses during COVID-19 AL St John, APS Rathore The Journal of Immunology 205 (3), 555-564, 2020 | 67 | 2020 |
| Chymase level is a predictive biomarker of dengue hemorrhagic fever in pediatric and adult patients H Tissera, APS Rathore, WY Leong, BL Pike, TE Warkentien, FS Farouk, ... The Journal of infectious diseases 216 (9), 1112-1121, 2017 | 59 | 2017 |
| Extended evaluation of virological, immunological and pharmacokinetic endpoints of CELADEN: a randomized, placebo-controlled trial of celgosivir in dengue fever patients C Sung, Y Wei, S Watanabe, HS Lee, YM Khoo, L Fan, APS Rathore, ... PLoS neglected tropical diseases 10 (8), e0004851, 2016 | 58 | 2016 |
| New perspectives on the origins and heterogeneity of mast cells AL St. John, APS Rathore, F Ginhoux Nature Reviews Immunology 23 (1), 55-68, 2023 | 51 | 2023 |
Ashley St. JohnDuke-National University of Singapore/Duke UniversityVerified email at duke.edu
